Bingyu Cai

ORCID: 0000-0002-2016-2352
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About
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Research Areas
  • Plant-Microbe Interactions and Immunity
  • Plant Pathogens and Fungal Diseases
  • Banana Cultivation and Research
  • Virus-based gene therapy research
  • Genomics and Phylogenetic Studies
  • Plant Disease Resistance and Genetics
  • CRISPR and Genetic Engineering
  • Growth and nutrition in plants
  • Biofuel production and bioconversion
  • Phytoplasmas and Hemiptera pathogens
  • Mycotoxins in Agriculture and Food
  • Anaerobic Digestion and Biogas Production
  • Robotic Path Planning Algorithms
  • Plant Micronutrient Interactions and Effects
  • Heavy Metals in Plants
  • Advanced Algorithms and Applications
  • Ferroptosis and cancer prognosis
  • Autophagy in Disease and Therapy
  • Plant nutrient uptake and metabolism
  • RNA modifications and cancer
  • Mycorrhizal Fungi and Plant Interactions
  • Plant Molecular Biology Research
  • Heavy metals in environment
  • Microbial Metabolic Engineering and Bioproduction
  • Metaheuristic Optimization Algorithms Research

Sanya University
2024-2025

Chinese Academy of Tropical Agricultural Sciences
2021-2025

University of Chinese Academy of Sciences
2024

Chinese Academy of Sciences
2024

State Key Laboratory of Stem Cell and Reproductive Biology
2024

Institute of Zoology
2024

Hainan University
2021-2023

Hainan Normal University
2021

Beijing Institute of Technology
2020

Suzhou Industrial Park Institute of Services Outsourcing
2020

Abstract Ferroptosis is a newly defined form of regulated cell death characterized by the iron-dependent accumulation lipid hydroperoxides. Erastin, ferroptosis activator, binds to voltage-dependent anion channels VDAC2 and VDCA3, but treatment with erastin can result in degradation channels. Here, authors show that Nedd4 induced following treatment, which leads ubiquitination subsequent Depletion limits protein VDAC2/3, increases sensitivity cancer cells erastin. By understanding molecular...

10.1038/s41467-020-14324-x article EN cc-by Nature Communications 2020-01-23

Banana Fusarium wilt caused by oxysporum f. sp. cubense (Foc) is the most destructive soil-borne fungal disease. Tropical race 4 (Foc TR4), one of strains Foc, can infect many commercial cultivars, which represents a threat to global banana production. Currently, there are hardly any effective chemical fungicides control To search for natural product-based controlling wilt, we identified novel strain Streptomyces yongxingensis nov. (JCM 34965) from marine soft coral, bioactive compound,...

10.1021/acs.jafc.2c02810 article EN Journal of Agricultural and Food Chemistry 2022-09-28

CRISPR-based gene therapies are making remarkable strides toward the clinic. But large size of most widely used Cas endonucleases including Cas9 and Cas12a restricts their efficient delivery by adeno-associated virus (AAV) for in vivo editing. Being exceptionally small, recently engineered type V-F CRISPR-Cas12f1 systems can overcome cargo packaging bottleneck present as strong candidates therapeutic applications. In this study, pairwise editing efficiencies different Cas12f1/sgRNA scaffold...

10.1002/advs.202308095 article EN cc-by Advanced Science 2024-02-26

Nitrogen is a crucial element for the growth and development of plants, directly affecting crop yield. To investigate physiological molecular mechanism nitrogen-deficiency stress, we conducted an investigation into effects different nitrogen levels on growth, photosynthetic characteristics, gene transcription banana seedlings. Compared with control group normal (NN), height plants receiving Reduced-N (NR), Low-N (LN), N-Free (NF) treatments was decreased by 0.45 cm, 2.5 3.25 respectively....

10.3390/horticulturae10030290 article EN cc-by Horticulturae 2024-03-18

The TGA (TGACG motif-binding factor) transcription factors are integral to root growth and development, pivotal in mediating plant responses abiotic stresses. Nonetheless, their role the nutrient absorption processes of banana plants has not been extensively investigated. This research conducted a comprehensive analysis MaTGA gene family, emphasizing physicochemical characteristics, phylogenetic relationships, duplication events, promoter cis-regulatory elements protein interaction networks....

10.3390/ijms26052168 article EN International Journal of Molecular Sciences 2025-02-28

Banana Fusarium wilt caused by oxysporum f. sp. cubense is a disastrous fungal disease. Foc tropical race 4 (Foc TR4) infects almost all banana cultivars. Use of chemical fungicides serious environment pollution. Biological control with antagonistic microbes promising strategy for controlling TR4. Here, strain WHL7 isolated from marine soft coral exhibited high antifungal activity against Based on the morphological and physicochemical profiles as well phylogenetic tree, was assigned to...

10.1094/pdis-06-21-1275-re article EN Plant Disease 2021-08-26

Banana Fusarium wilt caused by oxysporum f. sp. cubense tropical race 4 (Foc TR4) is one of the most destructive banana diseases in world, which limits development industry. Compared with traditional physical and chemical practices, biological control becomes a promising safe efficient strategy. In this study, strain Y1-14 strong antagonistic activity against Foc TR4 was isolated from rhizosphere soil plantation, where no disease symptom detected for more than ten years. The identified as...

10.3390/jof8121291 article EN cc-by Journal of Fungi 2022-12-09

Banana Fusarium wilt caused by oxysporum f. sp. cubense tropical race4 (Foc TR4) is one of the most destructive soil-borne fungal diseases and currently threatens banana production around world. Until now, there lack an effective method to control wilt. Therefore, it urgent find eco-friendly strategy against disease. In this study, a strain Trichoderma N4-3 was isolated newly from rhizosphere soil plants. The isolate identified as parareesei through analysis TEF1 RPB2 genes well...

10.3389/fpls.2023.1289959 article EN cc-by Frontiers in Plant Science 2023-10-24

Banana Fusarium wilt caused by oxysporum f. sp. cubense (Foc TR4) is the most destructive soil-borne fungal disease. Until now, there has been a lack of effective measures to control It urgent explore biocontrol agents Foc TR4 and secretion mycotoxin. In this study, fluvirucin B6 was screened from Streptomyces solisilvae using an activity-guided method. Fluvirucin exhibited strong antifungal activity against (0.084 mM EC50 value) significantly inhibited mycelial growth spore germination....

10.1021/acs.jafc.4c04077 article EN Journal of Agricultural and Food Chemistry 2024-07-31

Plant height is an important and valuable agronomic trait associated with yield resistance to abiotic biotic stresses. Dwarfism has positive effects on plant development field management, especially for tall monocotyledon banana (Musa spp.). However, several key genes their regulation mechanism of controlling during are unclear. In the present study, popular cultivar 'Brazilian banana' ('BX') its dwarf mutant ('RK') were selected identify height-related by comparing phenotypic transcriptomic...

10.3390/ijms24032628 article EN International Journal of Molecular Sciences 2023-01-30

Due to the lack of effective guidance on particle's speed and precocity in standard particle swarm optimization, a optimization basis gradient information time-varying acceleration coefficient (TVAC), namely descent (GDPSO), is proposed. By combining direct method indirect solve unconstrained problem, used modify velocity term, guide conduct local efficient search, improve global explore ability algorithm through strategy. On simulation experiment comparison with other algorithms, proposed...

10.1145/3424978.3424990 article EN Proceedings of the 4th International Conference on Computer Science and Application Engineering 2020-10-15

Mycotoxin contamination is a serious threat to the world agriculture and health. Fusarium oxysporum f. sp. cubense (Foc) soil-borne fungal pathogen that causes wilt of crops. Foc produces highly toxic mycotoxins such as fusaric acid (FA), beauvericin (BEA) fusarenone (FUS), which are cytotoxic carcinogenic. It urgent explore biofungicides inhibit secretion accumulation mycotoxin. Here, bioactive compound fluvirucin B6 was obtained from Streptomyces solisilvae with strong antifungal activity....

10.2139/ssrn.4718506 preprint EN 2024-01-01

Bananas are the world’s important fruit and staple crop in developing countries. Cadmium (Cd) contamination soils results decrease of yield food safety. Bioremediation is an environmental-friendly effective measure using Cd-tolerant plant growth promoting rhizobacteria (PGPR). In our study, a Cd-resistant PGPR Bacillus cereus 2-7 was isolated identified from discarded gold mine. It produced multiple biomolecules such as siderophores, indole-3-acetic acid (IAA),...

10.2139/ssrn.4442580 preprint EN 2023-01-01
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