A5059234887- Corneal Surgery and Treatments
- Ocular Surface and Contact Lens
- Corneal surgery and disorders
- Allelopathy and phytotoxic interactions
- Weed Control and Herbicide Applications
- Plant biochemistry and biosynthesis
- Glaucoma and retinal disorders
- Plant Parasitism and Resistance
- Plant tissue culture and regeneration
- Ocular Infections and Treatments
- Insect Resistance and Genetics
- Plant-Microbe Interactions and Immunity
- Pesticide and Herbicide Environmental Studies
- Insect and Pesticide Research
- Plant Stress Responses and Tolerance
- Beetle Biology and Toxicology Studies
- Immunotherapy and Immune Responses
- Plant Gene Expression Analysis
- Allergic Rhinitis and Sensitization
- Genomics and Phylogenetic Studies
- Pharmacogenetics and Drug Metabolism
- Microbial Metabolic Engineering and Bioproduction
- Insect-Plant Interactions and Control
- Immune Response and Inflammation
- Plant responses to water stress
Agricultural Research Service
2016-2025
Zhejiang University of Technology
2024-2025
United States Department of Agriculture
2013-2024
University of Mississippi
2008-2024
Nanjing University of Posts and Telecommunications
2024
Changsha University of Science and Technology
2024
National Clinical Research Center for Digestive Diseases
2024
Peking University
2024
Beijing Tongren Hospital
2013-2023
Capital Medical University
2013-2023
Although the function of silicon (Si) in plant physiology has long been debated, its beneficial effects on resistance against abiotic and biotic stresses, including insect herbivory, have well documented. In addition, jasmonate (JA) signaling pathway plays a crucial role mediating antiherbivore defense responses plants. However, potential interactions between JA Si response to attack not examined directly. To explore may play Si-enhanced resistance, we silenced expression allene oxide...
Resistance to glyphosate in weed species is a major challenge for the sustainability of use crop and non-crop systems. A glyphosate-resistant Italian ryegrass population has been identified Arkansas. This research was conducted elucidate its resistance mechanism.The investigation on resistant susceptible plants from Desha County, Arkansas (Des03). The amounts that caused 50% overall visual injury were 7 13 times greater than those same population. EPSPS gene did not contain any point...
A tall waterhemp population from Missisippi was suspected to be resistant glyphosate. Glyphosate dose response experiments resulted in GR 50 (dose required reduce plant growth by 50%) values of 1.28 and 0.28 kg ae ha −1 glyphosate for the glyphosate-resistant (GR) -susceptible (GS) populations, respectively, indicating a five-fold resistance. The absorption pattern 14 C-glyphosate between GS populations similar up 24 h after treatment (HAT). Thereafter, susceptible absorbed more (55 49%...
There is a popular demand for more natural means of pest management, including weed as well by farmers herbicides with new chemistries and/or modes action to which current resistances do not apply. Natural compounds offer source that can either meet these needs in their state or templates better physicochemical properties field use. In some cases, simply identifying good herbicide target site [...]
Guayule plants accumulate large quantities of rubber within parenchyma cells their stembark tissues. This is packed discrete organelles called particles composed primarily a lipophilic, cis-polyisoprene core, small amounts lipids, and several proteins, the most abundant which Mr53,000 particle protein (RPP). We have cloned sequenced full-length cDNA for RPP show that it has 65% amino acid identity 85% similarity to cytochrome P450 known as allene oxide synthase (AOS), recently identified...
Sorghum is considered to be one of the more allelopathic crop species, producing phytotoxins such as potent benzoquinone sorgoleone (2-hydroxy-5-methoxy-3-[(Z,Z)-8′,11′,14′-pentadecatriene]-p-benzoquinone) and its analogs. Sorgoleone likely accounts for much allelopathy spp., typically representing predominant constituent bicolor root exudates. Previous ongoing studies suggest that biosynthetic pathway this plant growth inhibitor occurs in hair cells, involving a polyketide synthase activity...
Cytochrome P450s exist ubiquitously in all organisms and are involved many biological processes. Allene oxide synthase (AOS) is a P450 enzyme that plays key role the biosynthesis of oxylipin jasmonates, which signal defense reactions higher plants. The crystal structures guayule (Parthenium argentatum) AOS (CYP74A2) its complex with substrate analog 13(S)-hydroxyoctadeca-9Z,11E-dienoic acid have been determined. exhibit classic fold but possess heme-binding mode an unusually long heme...
Abstract Sorghum bicolor is considered to be an allelopathic crop species, producing phytotoxins such as the lipid benzoquinone sorgoleone, which likely accounts for many of properties spp. Current evidence suggests that sorgoleone biosynthesis occurs exclusively in root hair cells and involves production alkylresorcinolic intermediate (5-[(Z,Z)-8′,11′,14′-pentadecatrienyl]resorcinol) derived from unusual 16:3Δ9,12,15 fatty acyl-CoA starter unit. This led suggestion involvement one or more...
Nitrogen (N) and silicon (Si) are two important nutritional elements required for plant growth, both impact host resistance toward insect herbivores. The interaction between the may therefore play a significant role in determining resistance. We investigated this rice (Oryza sativa L.) its effect on to herbivore brown planthopper Nilaparvata lugens (BPH). Our results indicate that high-level (5.76 mM) N fertilization reduced Si accumulation leaves, furthermore, decrease was likely due...
Among their responses to microbial infection, plants deploy an arsenal of natural antibiotic products. Historically these have been identified on the basis activity in vitro, which leaves open question relevance defense planta. The vast majority such products from important crop plant rice (Oryza sativa) are diterpenoids whose biosynthesis proceeds via either ent- or syn-copalyl diphosphate (CPP) intermediates, were isolated against fungal blast pathogen Magnaporthe oryzae. However, gene for...
Banana Fusarium wilt caused by oxysporum f. sp. cubense (Foc) is the most destructive soil-borne fungal disease. Tropical race 4 (Foc TR4), one of strains Foc, can infect many commercial cultivars, which represents a threat to global banana production. Currently, there are hardly any effective chemical fungicides control To search for natural product-based controlling wilt, we identified novel strain Streptomyces yongxingensis nov. (JCM 34965) from marine soft coral, bioactive compound,...
To evaluate optical coherence tomography meibography (OCT-M) in patients with and without obstructive meibomian gland dysfunction (MGD) to determine the relationship between OCT-M ocular surface clinical tests.Twenty-two MGD 16 control subjects were included. Each patient underwent an evaluation of disease symptoms, lid margin abnormality score, lipid layer thickness evaluation, (MG) morphological changes using noncontact infrared OCT-M. scans acquired 4 different locations. parameters...
Purpose. To evaluate the relationship between corneal and conjunctival epithelium thickness ocular surface clinical tests in dry eye disease (DED) patients. Patients Methods. Fifty-four patients with DED 32 control subjects were included. Each patient underwent an evaluation using index (OSDI), tear film break-up time (TBUT), staining, lipid layer analysis, Schirmer test. The central (CET), limbal (LET), bulbar (BET) acquired spectral-domain optical coherence tomography (SD-OCT). Results....
SUMMARY Tiller angle is an important determinant of plant architecture in rice ( Oryza sativa L.). Auxins play a critical role determining architecture; however, the underlying metabolic and signaling mechanisms are still largely unknown. In this study, we have identified member bZIP family TGA class transcription factors, OsbZIP49 , that participates regulation specifically expressed gravity‐sensing tissues, including shoot base, nodes lamina joints. Transgenic plants overexpressing...
Niemann–Pick disease type C (NPC) is a devastating lysosomal storage characterized by abnormal cholesterol accumulation in lysosomes. Currently, there no treatment for NPC. Transcription factor EB (TFEB), member of the microphthalmia transcription factors (MiTF), has emerged as master regulator function and promoted clearance substrates stored cells. However, it not known whether TFEB plays role NPC disease. Here, we show that transgenic overexpression TFEB, but TFE3 (another MiTF family)...
Summary Rice plants synthesize a unique group of diterpenoid phytoalexins (DPs) that exhibit broad‐spectrum antimicrobial activities and are biosynthesized by enzymes encoded three biosynthetic gene clusters. However, the regulatory mechanisms their biosynthesis remain unclear. Here, roles transcription factor OsWRKY10 its interacting VQ motif‐containing protein OsVQ8 in DPs disease resistance were investigated via genetic biochemical analyses. Their CRISPR/Cas9‐mediated knockout...
Niemann–Pick disease type C (NPC) is a devastating lysosomal storage characterized by abnormal cholesterol accumulation in lysosomes. Currently, there no treatment for NPC. Transcription factor EB (TFEB), member of the microphthalmia transcription factors (MiTF), has emerged as master regulator function and promoted clearance substrates stored cells. However, it not known whether TFEB plays role NPC disease. Here, we show that transgenic overexpression TFEB, but TFE3 (another MiTF family)...