A5091443349- Plant Virus Research Studies
- Plant and Fungal Interactions Research
- Plant Stress Responses and Tolerance
- Plant Disease Resistance and Genetics
- Plant Molecular Biology Research
- Insect-Plant Interactions and Control
- Plant-Microbe Interactions and Immunity
- Animal Virus Infections Studies
- Plant nutrient uptake and metabolism
- Molecular Biology Techniques and Applications
- Forensic and Genetic Research
- Photosynthetic Processes and Mechanisms
- Plant Pathogenic Bacteria Studies
- Chromosomal and Genetic Variations
- Insect symbiosis and bacterial influences
- Plant tissue culture and regeneration
- Insect Resistance and Genetics
- Wheat and Barley Genetics and Pathology
- Genetic Mapping and Diversity in Plants and Animals
- Plant Gene Expression Analysis
- Animal Disease Management and Epidemiology
- CRISPR and Genetic Engineering
- Insect and Pesticide Research
- RNA and protein synthesis mechanisms
- Transgenic Plants and Applications
Hunan Agricultural University
2014-2025
Shandong Normal University
2008-2025
Chinese Academy of Sciences
2021-2025
Shanghai Institute of Materia Medica
2025
Henan University
2025
Chinese Academy of Agricultural Sciences
2015-2024
Ruijin Hospital
2024
Shanghai Jiao Tong University
2024
Institute of Plant Protection
2013-2024
Liaoning Academy of Agricultural Sciences
2021-2024
Genome-wide association studies (GWAS) have linked common single nucleotide polymorphisms (SNPs) on chromosome 9p21 near the INK4/ARF (CDKN2A/B) tumor suppressor locus with risk of atherosclerotic diseases and type 2 diabetes mellitus. To explore mechanism this association, we investigated whether expression proximate transcripts (p16(INK4a), p15(INK4b), ARF, ANRIL MTAP) correlate genotype representative SNPs.We analyzed in purified peripheral blood T-cells (PBTL) from 170 healthy donors....
Abstract In yeast, the interaction of General Control Non‐derepressible 1 (GCN1) with GCN2 enables to phosphorylate eIF2α (the alpha subunit eukaryotic translation initiation factor 2) under a variety stresses. Here, we cloned AtGCN1 , an Arabidopsis homologue GCN1 . We show that directly interacts and is essential for phosphorylation salicylic acid (SA), ultraviolet (UV), cold stress amino deprivation conditions. Two mutant alleles, atgcn1‐1 atgcn1‐2 which are defective in eIF2α, showed...
Deltamethrin (DLM) is widely used in agriculture and the prevention of human insect-borne diseases. However, molecular mechanism DLM induced liver injury remains unclear to date. This study investigated potential that fibrosis quails. Japanese quails received resveratrol (500 mg/kg) daily with or without (45 exposure for 12 weeks. Histopathology, transmission electron microscopy, biochemical indexes, TUNEL, quantitative real-time PCR, western blot analysis were performed. hepatic steatosis,...
The ability to identify single-nucleotide mutations is critical for probing cell biology and precise detection of disease. However, the small differences in hybridization energy provided by single-base changes makes identification these challenging living cells complex reaction environments. Here, we report a class de novo-designed prokaryotic riboregulators that provide ultraspecific RNA capabilities vivo cell-free transcription-translation reactions. These single-nucleotide-specific...
Abstract Background The maize inbred line A188 is an attractive model for elucidation of gene function and improvement due to its high embryogenic capacity many contrasting traits the first reference genome, B73, other elite lines. lack a genome assembly limits use as functional studies. Results Here, we present chromosome-level using long reads optical maps. Comparison with B73 both whole-genome alignments read depths from sequencing identify approximately 1.1 Gb syntenic sequences well...
Bats are associated with the circulation of most mammalian filoviruses (FiVs), pathogenic ones frequently causing deadly hemorrhagic fevers in Africa. Divergent FiVs have been uncovered Chinese bats, raising concerns about their threat to public health. Here, we describe a long-term surveillance track bat at orchards, eventually resulting identification and isolation FiV, Dehong virus (DEHV), from Rousettus leschenaultii bats. DEHV has typical filovirus-like morphology wide spectrum cell...
Secreted small cysteine-rich proteins (SCPs) play a critical role in modulating host immunity plant-pathogen interactions. Bioinformatic analyses showed that the fungal pathogen Verticillium dahliae encodes more than 100 VdSCPs, but their roles host-pathogen interactions have not been fully characterized. Transient expression of 123 VdSCP-encoding genes Nicotiana benthamiana identified three candidate involved The these proteins, VdSCP27, VdSCP113, and VdSCP126, N. resulted cell death...
Although most known viruses infecting fungi pathogenic to higher eukaryotes are asymptomatic or reduce the virulence of their host fungi, those that confer hypervirulence entomopathogenic fungus still need be explored. Here, we identified and studied a novel mycovirus in Metarhizium flavoviride , isolated from small brown planthopper ( Laodelphax striatellus ). Based on molecular analysis, tentatively designated as partitivirus 1 (MfPV1), species genus Gammapartitivirus family Partitiviridae...
Abstract Background MicroRNAs are key regulators of plant growth and development with important roles in environmental adaptation. The microRNAs from the halophyte species Thellungiella salsuginea (salt cress), which exhibits extreme salt stress tolerance, remain to be investigated. sequenced genome T. availability high-throughput sequencing technology enabled us discover conserved novel miRNAs this species. It is interesting identify wide study their response. Results In study, two small...
A key enzyme in the shikimate pathway, 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) is primary target of broad-spectrum herbicide glyphosate. Identification new aroA genes coding for EPSPS with a high level glyphosate tolerance essential development glyphosate-tolerant crops. In present study, five bacterial was evaluated E. coli aroA-defective strain ER2799 and transgenic tobacco plants. All could complement ER2799, AM79 showed highest tolerance. Although treatment inhibited growth...
Abstract Barley yellow dwarf virus-GPV (BYDV-GPV) is transmitted by Rhopalosiphum padi and Schizaphis graminum in a persistent nonpropagative manner. To improve our understanding of its transmission mechanism aphid vectors, we used two approaches, isobaric tags for relative absolute quantitation (iTRAQ) yeast two-hybrid (YTH) system, to identify proteins R. that may interact with or direct the spread BYDV-GPV along circulative pathway. Thirty-three differential viruliferous nonviruliferous...
The "green revolution" gene gibberellin oxidase contributes to the semidwarf phenotype, improving product and lodging resistance. Dissecting function of GA biosynthetic genes would be helpful for dwarf maize breeding. In this study, we edited GA20ox3 generated plants using CRISPR/Cas9 technology. Application exogenous can recover indicating that mutants are deficient. contents GA12 GA53 were elevated in due disruption GA20 oxidase, whereas other precursors (GA15, GA24, GA9, GA44, GA20)...
Abstract Background Ralstonia solanacearum causes bacterial wilt disease in tomato and other crops resulting huge economic losses worldwide. Several measures have been explored for the control of R. , but desired level through sustainable ecofriendly way is still awaited. Main body In this study, fungal metabolites produced by Trichoderma harzianum were investigated form crude extract management both vitro planta plants. investigation, checked their antibacterial potential at different...
Salt stress is a severe environmental factor that detrimentally affects wheat growth and production worldwide. Previous studies illustrate exogenous jasmonic acid (JA) significantly improved salt tolerance in plants. However, little known about the underlying molecular mechanisms of JA induced physiochemical changes seedlings under conditions. In this study, biophysiochemical transcriptome analysis was conducted to explore wheat. Exogenous increased by alleviating membrane lipid oxidation,...
Summary High temperature is one of several major abiotic stresses that can cause substantial loss crop yields. Heat shock proteins (HSPs) are key components heat stress resistance. Mutation FES1A, an auxiliary molecular chaperone HSP70, leads to defective acquired thermotolerance. Autophagy a positive regulator basal thermotolerance and negative memory, but its function in unclear. We found blocking constitutive autophagy rescued the sensitivity fes1a Arabidopsis thaliana . Immunoblot...