A5101658726- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Geological and Geochemical Analysis
- Nanoparticle-Based Drug Delivery
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Mycobacterium research and diagnosis
- DNA Repair Mechanisms
- HIV/AIDS drug development and treatment
- Geological and Geophysical Studies
- Drug Transport and Resistance Mechanisms
- Protist diversity and phylogeny
- HIV Research and Treatment
- High-pressure geophysics and materials
- Tuberculosis Research and Epidemiology
- earthquake and tectonic studies
- Geothermal Energy Systems and Applications
- MicroRNA in disease regulation
- Glycosylation and Glycoproteins Research
- Epigenetics and DNA Methylation
- Graphene and Nanomaterials Applications
- RNA Research and Splicing
- Chemotherapy-induced cardiotoxicity and mitigation
Yangtze University
2023-2024
Nanjing Medical University
2012-2020
First Affiliated Hospital of Wenzhou Medical University
2016
Zhejiang University
2014-2016
Wenzhou Medical University
2016
Emerging evidence has shown that dysregulation function of long non-coding RNAs (lncRNAs) implicated in gastric cancer (GC). However, the role differentially expressed lncRNAs GC not fully explained.LncRNA expression profiles were determined by lncRNA microarray five pairs normal and tissues, further validated another 75 paired tissues quantitative real-time PCR (qRT-PCR). Overexpression MT1JP was conducted to assess effect vitro vivo. The biological functions demonstrated luciferase...
// Mulong Du 1, * , Weizhi Wang 2, Hua Jin 3, Qiaoyan 1 Yuqiu Ge Jiafei Lu Gaoxiang Ma Haiyan Chu 4 Na Tong Haixia Zhu 3 Meilin Fulin Qiang Zhengdong Zhang Department of Environmental Genomics, Jiangsu Key Laboratory Cancer Biomarkers, Prevention and Treatment, Center, Nanjing Medical University, Nanjing, China 2 General Surgery, the First Affiliated Hospital Core Laboratory, Nantong Tumor Hospital, Nantong, Genetic Toxicology, Modern Toxicology Ministry Education, School Public Health,...
The integrated analytical strategy identified both genetic and epigenetic biomarkers for gastric cancer etiology.
Human 8-oxoguanine DNA glycosylase (hOGG1) is known to play an important role in the prevention of carcinogenesis, including gastric cancer (GC). We performed a case-control study investigate whether single nucleotide polymorphisms (SNPs) hOGG1 are associated with GC risk Chinese population. Two potential functional tagSNPs (rs159153 and rs1052133) previously reported SNP (rs125701) were genotyped 1,275 patients 1,436 controls. found that rs125701 G > A was significantly increased [adjusted...
P-glycoprotein (P-gp) overexpression has become the most common cause of occurrence multidrug resistance in clinical settings. We aimed to construct a micellar polymer carrier sensitize drug-resistant tumors doxorubicin (DOX). This A-B-C-type amphiphilic copolymer was prepared by sequential linkage β-cyclodextrin, hydrophobic poly(d,l-lactide), and hydrophilic poly(ethylene glycol). Upon incubation DOX-loaded micelles with DOX-resistant human breast carcinoma MCF-7/ADR cells, significantly...
As a passive rift basin in the Cenozoic, formation and evolution process of Weihe Basin has not been well explained. Here we estimate stretching factor basal heat flow for each period along four geological profiles using 2D multi-stage finite extension model. The modelling is based on reconstruction pre-rift crustal lithospheric thicknesses, calibrated with current flow. Xi'an Depression had biggest while Pucheng Uplift smallest throughout Cenozoic period, which saw range factors from 1.02...