A5078746490- Oceanographic and Atmospheric Processes
- RNA modifications and cancer
- Monoclonal and Polyclonal Antibodies Research
- Ubiquitin and proteasome pathways
- Genetic and Kidney Cyst Diseases
- Cancer-related gene regulation
- Helicobacter pylori-related gastroenterology studies
- Cell Image Analysis Techniques
- Cancer Research and Treatments
- Tropical and Extratropical Cyclones Research
- Biotin and Related Studies
- Angiogenesis and VEGF in Cancer
- Cancer, Hypoxia, and Metabolism
- Ocean Waves and Remote Sensing
- Cancer-related molecular mechanisms research
- Microtubule and mitosis dynamics
- Protist diversity and phylogeny
- Proteoglycans and glycosaminoglycans research
- Chemical Reactions and Isotopes
- Atmospheric and Environmental Gas Dynamics
- Cancer-related Molecular Pathways
- Infrared Thermography in Medicine
- Environmental Changes in China
- Otitis Media and Relapsing Polychondritis
- Advanced Computational Techniques and Applications
Institute of Atomic and Molecular Sciences, Academia Sinica
2017-2023
Xiamen Chang Gung Hospital
2016-2022
Academia Sinica
2016
PLA Army Engineering University
2005-2014
Second Affiliated Hospital of Fujian Medical University
2012
Fujian Medical University
2009-2012
Hunan University of Science and Technology
2011
Laboratoire d’Électronique, Informatique et Image
2009
Jiangsu Institute of Meteorological Sciences
2008
National Central University
2005-2007
A dynamic vibration absorber reduces the influence of a force whose excitation frequency nearly coincides with natural rotating machine. However, performance this type passive can be affected by changes in environment. In paper, we describe voice coil motor (VCM) that serve as actuator an active which regulated for different conditions. With VCM, suitable controllers designed periodic rejection using characteristics notch filter combination root-locus theorem. We have evaluated both...
Objective: Gastric cancer (GC) is a highly heterogeneous malignant carcinoma. This study aimed to conduct an exosome-based classification for assisting personalized therapy GC. Methods: Based on the expression profiling of prognostic exosome-related genes, GC patients in The Cancer Genome Atlas (TCGA) cohort were classified using unsupervised consensus clustering approach, and reproducibility this was confirmed GSE84437 cohort. An gene signature developed via Least Absolute Shrinkage...
TRAF6 has been reported to be associated with poor prognosis in non-small-cell lung cancer (NSCLC). However, its precise role tumor development not elaborated. In the present study, function and mechanism by which contributes were intensively investigated. was found overexpressed primary NSCLC tissue all tested cell lines. Knockdown of shRNA substantially attenuated proliferation anchorage-independent growth. Moreover, glycolysis, such as glucose consumption lactate production, also...
Abstract Based on the 1958~1995 global monthly average SSTA field reanalysis data supported by NCEP/NCAR, using dynamical system retrieve idea and GA approach, parameters of El Nino/La Nina exponential forecast model were optimized non‐linear Nino3 index was established from above SST time series. The analytical results test show that which has advantages optimum search side‐by‐side calculation can externally, exactly expediently model. So it effectively event afford useful investigative...
Aiming at tackling the difficulty in establishing a sea surface temperature (SST) dynamical model, this study develops non-linear dynamical–statistical model of SST fields and their correlative factors based on Genetic Algorithms (GA) system reconstruction idea, which greatly improves El Niño–Southern Oscillation (ENSO) forecast model. Using Hadley data, wind (SSW) level pressure (SLP) data from National Centers for Environmental Prediction-National Center Research (NCEP-NCAR), with...
The third South China Sea (SCS) air-sea flux experiment was conducted in Xisha sea area from April 24 to June 22, 2002. heat (latent and sensible heat) exchange momentum were computed using eddy-correlation method TOGA COARE2.5b algorithms. Variation of radiation components, moisture their relations with synoptic condition discussed. results indicate that fluxes, especially short-wave radiation, net budget ocean surface, latent oceanic flux, changed significantly before after the onset SCS...
Abstract Distal appendages (DAPs) are nanoscale, pinwheel-like structures protruding from the distal end of centriole that mediate membrane docking during ciliogenesis, marking cilia base around ciliary gate. Here, we determined a superresolved multiplex 16 centriole-distal-end components. Surprisingly, rather than pinwheels, intact DAPs exhibit cone-shaped architecture with components filling space between each pinwheel blade, new structural element termed appendage matrix (DAM)....
Abstract Microscopy-guided proteomics at an organelle-dimension resolution is desired for revealing unknown protein constituents specific disease- or functional-associated regions the molecular-molecular interactions level. Here, we achieve spatial purification by introducing a firmware-integrated microscopy platform that triggers in situ subcellular photo-biotinylation of proteins user-defined interest (ROIs) one field view (FOV) time thousands FOVs fully automatically. An illumination...
Objective To study the clinical effects and side of recombinant human vascular endostatin combined with pemetrexed cisplatin in treatment advanced lung adenocarcinoma. Methods Forty-seven patients adenocarcinoma were recruited from Jan 2011 to 2013, they randomly divided into experimental group control group. The (n = 24) was added based on cisplatin,whereas group(n 23) administered only. objective response rate (ORR), disease (DCR), progressive (PD) rate, progression-free survival...
Abstract High-sensitivity hypothesis-free subcellular proteomics is challenging due to the limited sensitivity of mass spectrometry and lack amplification tools for proteins. Without such technology, it not possible discover proteins at specific locations interest in cells or tissue samples. Here, we introduce a total-sync ultra-content microscopic system termed MicroscoopTM that integrates microscopy, optics, FPGA-based mechatronics, photochemistry, deep learning computer vision enable...