- Analytical Chemistry and Chromatography
- Effects and risks of endocrine disrupting chemicals
- Advanced biosensing and bioanalysis techniques
- Biosensors and Analytical Detection
- Pesticide Residue Analysis and Safety
- Advanced Chemical Sensor Technologies
- Analytical chemistry methods development
- Natural product bioactivities and synthesis
- Mass Spectrometry Techniques and Applications
- Toxic Organic Pollutants Impact
- Electrochemical Analysis and Applications
- Electrochemical sensors and biosensors
- Dye analysis and toxicity
- Phytochemical Studies and Bioactivities
- Indoor Air Quality and Microbial Exposure
- Traditional Chinese Medicine Analysis
- Antibiotics Pharmacokinetics and Efficacy
- Microplastics and Plastic Pollution
- Chromatography in Natural Products
- Pharmacogenetics and Drug Metabolism
- Advanced Nanomaterials in Catalysis
- Tea Polyphenols and Effects
- Water Treatment and Disinfection
- Recycling and Waste Management Techniques
- Contact Dermatitis and Allergies
Hebei Agricultural University
2025
Jiujiang University
2014-2024
Chinese Academy of Inspection and Quarantine
2015-2024
Fudan University
2024
Southern Medical University
2019-2023
Nanfang Hospital
2019-2023
Chongqing Metrology Quality Inspection and Research Institute
2021
Research Center for Eco-Environmental Sciences
2021
Chinese Academy of Sciences
2021
Jiangxi University of Traditional Chinese Medicine
2021
Abstract Compared with noble metals, semiconductors surface plasmon resonance effect are another type of SERS substrate materials. The main obstacles so far that the semiconducting materials often unstable and easy to be further oxidized or decomposed by laser irradiating contacting corrosive substances. Here, we report metallic MoO 2 can used as a detect trace amounts highly risk chemicals including bisphenol A (BPA), dichloropheno (DCP), pentachlorophenol (PCP) on. minimum detectable...
The extensive applications of parabens in foods, drugs, and cosmetics cause inevitable exposure to humans. Revealing the developmental toxicity is utmost importance regarding their safety evaluation. In this study, effects four commonly used parabens, including methyl paraben (20 ∼ 200 μM), ethyl 100 propyl (5 20 butyl (BuP, 2 10 were investigated on early development zebrafish embryos larvae. underlying mechanisms explored from aspect disturbance thyroid endocrine system using vivo, vitro,...
Isotopic labeling of cysteine residues with acrylamide was previously utilized for relative quantitation proteins by MALDI-TOF. Here, we explored and compared the application deuterated (13)C isotopes quantitative proteomic analysis using LC-MS/MS high-resolution FTICR mass spectrometry. The method applied to human serum samples that were immunodepleted abundant proteins. Our results show reliable across an abundance range spans 5 orders magnitude based on ion intensities known protein...
The design and development of multifunctional carriers for drug delivery based on hollow nanoparticles (HNPs) have attracted intense interests. Ordinary spherical HNPs are demonstrated to be promising candidates. However, the application with special morphologies has rarely been reported. sharp horns expected own higher endocytosis efficiencies than counterparts. In this work, novel starlike silica (SHNPs) different sizes proposed as platforms fabrication redox-triggered systems synergy gene...
Sensitive detection of severe fever with thrombocytopenia syndrome virus (SFTSV) by a point-of-care assay is great significance for promoting clinical diagnosis. In this work, ultrasensitive SFTSV was achieved using fluorescent carbon dots/SiO2 nanospheres (CSNs) as reporters lateral flow assay. The prepared CSNs were resistant to extreme environments and had strong stability. uniform the size about 200 nm obtained differential centrifugation. Their absolute quantum yields in aqueous solid...
An efficient and sensitive chiral analytical method was established for the determination of fungicide prothioconazole its major metabolite prothioconazole-desthio in agricultural environmental samples using ultraperformance liquid chromatography–tandem mass spectrometry. The optical rotation absolute configuration enantiomers were identified by detector electronic circular dichroism spectra. elution order R-(+)-prothioconazole-desthio, S-(−)-prothioconazole-desthio, R-(−)-prothioconazole,...
This paper reports the non-targeted analysis of unknown volatile chemicals in medical masks through headspace gas chromatography-Orbitrap high-resolution mass spectrometry. In view difficulties that may be encountered qualitative substances, several typical cases and corresponding reliable solutions are given from perspective comprehensive score retention index, chemical ionization identification molecular formula, fragment ion detail comparison for distinguishing isomers, alkanes. With this...
A novel and effective method for enantioselective determination of flutriafol enantiomers in food environmental matrices (cucumber, tomato, grape, pear, wheat, soil, water) has been developed. The (R)-(-)-flutriafol was first eluted measured from electronic circular dichroism spectra using a cellulose tris(3-chloro-4-methyl phenyl carbamate) chiral column. mean recoveries the samples ranged 82.9% to 103.4%, with intraday relative standard deviations (RSD) 2.2-8.3% interday RSD 3.4-7.9%. Good...
Early diagnosis of tumor markers is great importance for the successful treatment cancer. As a high-throughput and high-sensitivity detection technology, liquid suspension biochips based on quantum dot (QD) encoded microspheres have been widely used in immunodetection markers. In this work, maleic anhydride grafted PLA (PLA-MA) encoding were as carriers phase immunoassay PLA-MA fluorescent beads are prepared by embedding CdSe/ZnS dots using Shirasu porous glass (SPG) membrane emulsification...
The root of Paris polyphylla (RPP) is widely used as a traditional Chinese medicine for long time due to the good properties heat-clearing and detoxicating, detumescence, sedation, acesodyne haemostasis. To clarify on bioactive substances ensure safety in clinical medication, feasible accurate strategy was developed by applying high-performance liquid chromatography coupled electrospray ionisation quadrupole time-of-flight-mass spectrometry (HPLC-ESI-QTOF-MS/MS). Separation performed an...
New mosquito repellent products (NMRPs) are emerging popular repellents among children. There increasing reports on children's sensitization reactions caused by NMRPs, while regulations their productions, sales, or usage still lacking. One of the reasons could be missing comprehensive risk assessment. We first conducted a nationwide investigation NMRP preferences. Then, we high-throughput screened volatile semivolatile organic chemicals (VOCs/SVOCs) in five representative NMRPs headspace gas...