A5053015332- Palliative Care and End-of-Life Issues
- Pain Management and Opioid Use
- Cancer survivorship and care
- Respiratory Support and Mechanisms
- Grief, Bereavement, and Mental Health
- Pharmacological Effects and Toxicity Studies
- Health Systems, Economic Evaluations, Quality of Life
- Pain Mechanisms and Treatments
- Childhood Cancer Survivors' Quality of Life
- Patient Dignity and Privacy
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Pediatric Pain Management Techniques
- Multiple Myeloma Research and Treatments
- Cancer Treatment and Pharmacology
- Cancer, Stress, Anesthesia, and Immune Response
- Patient-Provider Communication in Healthcare
- Anesthesia and Pain Management
- Family and Patient Care in Intensive Care Units
- Ethics in medical practice
- Global Cancer Incidence and Screening
- Mental Health and Patient Involvement
- Lung Cancer Diagnosis and Treatment
- Economic and Financial Impacts of Cancer
- Frailty in Older Adults
- Bone health and treatments
NIHR Clinical Research Network
2018-2025
National Institute for Health Research
2018-2025
University of Leeds
2018-2025
University of Sheffield
2015-2024
Royal Hallamshire Hospital
2004-2021
Sheffield Teaching Hospitals NHS Foundation Trust
2008-2014
University of Manchester
2004-2014
Aston University
2006
University of St Andrews
2004
St Michael's Hospital
1998
Background : In 1986, the European Organization for Research and Treatment of Cancer (EORTC) initiated a research program to develop an integrated, modular approach evaluating quality life patients participating in international clinical trials. Purpose We report here results field study practicality, reliability, validity EORTC QLQ-C30, current core questionnaire. The QLQ-C30 incorporates nine multi-item scales: five functional scales (physical, role, cognitive, emotional, social); three...
Objectives: To explore the attitudes of older people towards home as a place care when dying. Design: A two-phase qualitative study using focus groups and semi-structured interviews. Participants: Eight group discussions were held with 32 participants recruited from six purposively selected community representing in Sheffield, UK. further 16 men 29 women participated Results: Participants identified that was more than physical location, familiarity, comfort presence loved ones. While...
Purpose Eicosapentaenoic acid (EPA) has been proposed to have specific anticachectic effects. This trial compared EPA diethyl ester with placebo in cachectic cancer patients for effects on weight and lean body mass. Patients Methods Five hundred eighteen weight-losing advanced gastrointestinal or lung were studied a multicenter, double-blind, controlled trial. randomly assigned receive novel preparation of pure at dose 2 g 4 daily (2g EPA, n = 175; 172; placebo, 171). assessed weeks 8 weeks....
is possible because of proximity to others with contagious diseases (ie, resulting from direct person-to-person transmission).
Objective: An examination of whether oxycodone/naloxone prolonged-release tablets (OXN PR) can improve constipation and maintain analgesia, compared with oxycodone (OxyPR) in patients moderate/severe cancer pain. Methods: Randomized, double-blind, active-controlled, double-dummy, parallel-group study which 185 were randomized to receive up 120 mg/day OXN PR or OxyPR over 4 weeks. Efficacy assessments included Bowel Function Index (BFI), Brief Pain Inventory Short-Form (BPI-SF), laxative...
A definition of rectal cancer is important for optimal planning neoadjuvant therapy and surgical strategy. Anatomically the rectum distal to sigmoid colon its upper limit termination mesocolon. commonly used an adenocarcinoma with a margin at or below 15 cm from anal verge, measured by rigid sigmoidoscopy. Standard anatomical texts put this level third sacral vertebra (Williams & Warwick, 1980) but it generally agreed surgeons that starts promontory (UKCCCR, 1989). Whilst there remains...
<h3>ABSTRACT</h3> Care of people in their last days life should be based on compassion, respect and, wherever possible, research evidence. Previously the Liverpool Pathway attempted to facilitate this but it was withdrawn after an independent government report found that its uncritical implementation could lead poor care. This Concise Guideline overviews NICE Clinical (NG31), which addresses: recognising dying; communication and shared decision making; maintaining hydration; pharmacological...
Objective. This discussion document about the management of cancer pain is written from specialists' perspective in order to provoke thought and interest a multimodal approach pain, not just towards end life, but at diagnosis, as consequence therapies, survivors. It relates science clinical setting explains role psychological, physical, interventional complementary therapies pain. Methods. has been produced by consensus group relevant health care professionals United Kingdom patients'...
Objective. This discussion document about the management of cancer pain is written from specialists' perspective in order to provoke thought and interest a multimodal approach pain, not just towards end life, but at diagnosis, as consequence therapies, survivors. It relates science clinical setting explains role psychological, physical, interventional complementary therapies pain. Methods. has been produced by consensus group relevant healthcare professionals United Kingdom patients'...