- COVID-19 Clinical Research Studies
- Hydrogen's biological and therapeutic effects
- Medical and Biological Ozone Research
- Biochemical and Molecular Research
- Anesthesia and Pain Management
- Autophagy in Disease and Therapy
- Digital Imaging for Blood Diseases
- Hemodynamic Monitoring and Therapy
- Cardiac, Anesthesia and Surgical Outcomes
- Intensive Care Unit Cognitive Disorders
- Family and Patient Care in Intensive Care Units
- Respiratory Support and Mechanisms
- Selenium in Biological Systems
- Long-Term Effects of COVID-19
- Epigenetics and DNA Methylation
Institute of International Relations of Moldova
2023-2024
Mendel University in Brno
2023
Nicolae Testemițanu State University of Medicine and Pharmacy
2022-2023
Radiation Oncology Institute
2023
Asociaţia Femeilor de Afaceri
2023
Introduction. Oxygen-ozone therapy stands as a medically endorsed practice confirmed by numerous international clinical studies. Various authors have illustrated the beneficial outcomes of ozone in terms its capacity to regulate redox balance, cellular inflammatory responses, and adaptation ischemia/reperfusion processes. Ozone extends encompass range viral infections, disorders, degenerative ailments, used both monotherapy an adjunct unified conventional therapies. Material methods....
ntroduction. During COVID-19 pandemic, non-invasive ventilation (NIV) was widely used during Pandemic. The factors predicting NIV failure in patients remain debatable. goal of this research is to identify the parameters that may correlate failure. Materials and methods. A retrospective analysis patients’ data, who were admitted ICU Institute Emergency Medicine, Chisinau, July-October 2020 connected NIV. study analyzed demographics, laboratory respiratory (at admission, at initiation, 24-48h...
Introduction Ozone therapy can be used as a monotherapy or an adjunctive treatment to standard COVID-19 protocols. Current evidence indicates that this approach may improve clinical outcomes, paraclinical markers, and reduce radiological signs of inflammation, with no side effects. Material methods he study included 100 consecutive patients aged 18 older COVID-19, admitted the Intensive Care Unit at Institute Emergency Medicine. Patients were randomly divided into two groups: 50 underwent...
Valoarea diagnostică și
Introduction. Evaluation of patient volemia arriving at a medical service today still represents challenge for specialists, especially in those who need surgical and anesthetic intervention. One the most common systemic side effect to anesthesia is hypotension. Spinal Anesthesia-Induced Hypotension (SAIH) because sympathetic blockade frequently cited as complication subarachnoid anesthesia, its severity being influenced by patient’s volemic state. The aim this literature review analyze if...
OBJECTIVES: Cisplatin is a widely used anticancer drug for the treatment of many solid cancers.DNA damage thought to be key mechanism cisplatin's activity.However, cisplatin may also affect cellular metabolism.The aim this study was determine effect on types ATP production (OXPHOS versus glycolysis) and their rate in prostate cancer cells potentially protective autophagy amino acids during treatment.We wanted investigate potential synergy between metabolic effects inhibition...
Introduction and objectives: There is still no specific treatment strategies aside from supportive management of huge amount fatal Pandemic COVID-19 cases. The use ozone (O3) gas as a therapy in alternative medicine has attracted skepticism due to its unstable molecular structure. Today we can affirm strongly that capable modulate inflammation acting on the "cytokine storm", reduce tissue hypoxia, decrease hypercoagulability impaired viral replication. Due many uncertainties around COVID-19,...
Introduction. Contemporary researchers have suggested and demonstrated the hypothesis that elevated level of D-dimers, which is a valuable marker coagulation fibrinolysis activation, can predict severity COVID-19, pulmonary complications, thromboembolic events before they occur. Material methods. The bibliographic resources were analyzed selected from databases such as PubMed, Hinari, SpringerLink, Google Search using keywords “COVID-19,” “SARS-CoV-2,” “coronavirus,” “D-dimers,”...
Introduction: The recorded studies suggest that there is clear evidence-based association between various laboratory biomarkers and COVID-19 disease severity. These marker levels reflect the intensity of cytokine-mediated hyperinflammatory response, which strongly associated with a poor outcome SARS-CoV-2 infection. Conclusions: C-reactive protein not only systemic inflammatory marker, but also an important regulator processes. level this positively correlated can be widely used to predict...
Background: Analysis and evaluation of the multitude parameters that impact mirror clinical evolution COVID-19 infection. Narrative literature review type study. Bibliographic search PubMed database, applying keywords: ”SARS-CoV-2”, ”COVID-19”, ”risk score”, ”laboratory parameters”, ”pathophysiology”, ”cytokine storm”, ”imaging evaluation”, “outcomes”, “clinical evolution”, which were combined with each other. There selected English-language publications, in extenso, published recognized...