A5038633223- Fusion materials and technologies
- Advanced biosensing and bioanalysis techniques
- Hydrocarbon exploration and reservoir analysis
- Nanoplatforms for cancer theranostics
- Nuclear Materials and Properties
- Adsorption and biosorption for pollutant removal
- Nuclear reactor physics and engineering
- Soil and Unsaturated Flow
- Gold and Silver Nanoparticles Synthesis and Applications
- Luminescence and Fluorescent Materials
- Geochemistry and Elemental Analysis
- Photodynamic Therapy Research Studies
- Radioactive element chemistry and processing
- Mesoporous Materials and Catalysis
- Electrochemical sensors and biosensors
- Soil erosion and sediment transport
- Zeolite Catalysis and Synthesis
- Methane Hydrates and Related Phenomena
- Atmospheric and Environmental Gas Dynamics
- Hydraulic Fracturing and Reservoir Analysis
- Molecular Sensors and Ion Detection
- Landslides and related hazards
- Chemical Synthesis and Characterization
- Nuclear and radioactivity studies
- ATP Synthase and ATPases Research
Ningxia University
2024
State Key Laboratory of Medicinal Chemical Biology
2021-2024
Nankai University
2013-2024
Jiangsu University
2014-2023
Ministry of Agriculture and Rural Affairs
2023
Jiangsu Academy of Agricultural Sciences
2020-2023
North China Electric Power University
2017-2022
Shanghai University of Traditional Chinese Medicine
2012-2021
Seventh People's Hospital of Shanghai
2021
China University of Petroleum, East China
2017-2018
In recent years, cancer phototherapy has been extensively studied as noninvasive treatment. To present efficient recognition toward cells, most photosensitizers (PSs) are required to couple with tumor-targeted ligands. Interestingly, the heptamethine cyanine IR780 displays an intrinsic feature even without modification. However, photothermal efficacy and photostability of not sufficient enough for clinical use. Herein, we involve a twisted structure tetraphenylethene (TPE) between two...
Glucose, a critical source of energy, directly determines the homeostasis human body. However, due to lack robust imaging probes, mechanism underlying changes glucose in body remains unclear. Herein, diboronic acid probes with good biocompatibility and high sensitivity were synthesized based on an ortho-aminomethylphenylboronic probe, phenyl(di)boronic (PDBA). Significantly, by introducing water-solubilizing group -CN opposite boronic -COOCH3 or -COOH groups β site anthracene PDBA, we...
Myocardial infarction (MI) is one of the leading causes death. Wilms' tumor 1-associating protein (WTAP), components m6A methyltransferase complex, has been shown to affect gene expression via regulating mRNA modification. Although WTAP implicated in various diseases, its role MI unclear. In this study, we found that hypoxia/reoxygenation (H/R) time-dependently increased expression, which turn promoted endoplasmic reticulum (ER) stress and apoptosis, human cardiomyocytes (AC16). H/R effects...
Low-temperature photothermal therapy (PTT) has the advantage of causing less damage to normal tissues and attracted great attention in recent years. However, efficacy low-temperature PTT is restricted by overexpression heat shock proteins (HSPs), specifically HSP70 HSP90. Inhibiting function these HSPs a major strategy used development new cancer therapies. Herein, we designed four T780T-containing thermosensitive nanoparticles interrupt energy supply for HSP expression using their TPP-based...
Pyroptosis has been reported to improve the antitumor effect by evoking a more intense immune response and therapeutic effect. For phototherapy, several photosensitizers have found initiate pyroptosis. However, of pyroptosis associated with apoptosis in enhancing therapy needs sufficient characterization, especially under long-term treatment. As NIR photosensitizer, heptamethine cyanines discovered for anticancer phototherapy deep tissue penetration inherent tumor-targeted capability. they...
Abstract Helicobacter pylori ( H. ) infection has been the leading cause of gastric cancer development. In recent years, resistance against antibiotic treatment a great challenge for most countries worldwide. Since biofilm formation is one reasons , and phototherapy emerged as promisingly alternative antibacterial treatment, herein bacteria‐targeted near‐infrared (NIR) photosensitizer (T780T‐Gu) by combining positively‐charged guanidinium (Gu) with an efficient phototherapeutic agent T780T...
Samples from seven major exploration wells in Biyang Depression of Henan Oilfield were compared using low-temperature nitrogen adsorption and shale oil experiments. Comprehensive analysis pore development, oiliness flowability was conducted by combining fractal dimension. The results show that the dimension negatively correlated with average size positively specific surface area. Compared large pore, small has great dimension, indicating structure is more complicated. Using S 1 chloroform...
An amplified and stable electrochemiluminescent signal of lucigenin on electrochemically reduced graphene oxide-containing sensing platform was obtained, exhibited obvious analytical properties towards bisphenol A.
The investigation into the impact of gravel on water infiltration process and hydraulic parameters in stony soil could offer a theoretical basis to enhance availability rocky mountain area. A one-dimensional vertical experiment was used this study. Six groups content 0% (CK), 10% (W1), 20% (W2), 30% (W3), 40% (W4) 50% (W5) were established explore changes wetting front, cumulative volume rate. Then accuracy four models simulating processes evaluated. Finally, Hydrus-1D perform numerical...
Recently, nanoformulations have been widely applied in the delivery of organic photothermal agents (OPTAs) for cancer therapy to prolong blood circulation or improve tumor-targeting capacity. However, systematic evaluations their effects on behavior OPTAs are limited, especially different types nanoparticle systems. Herein, we prepared two kinds nanoparticles (BSA and PEG (NPs)) load an OPTA, a cyanine photosensitizer (IR780-O-TPE), investigated response, organelle targeting, vivo...
The zinc injection process has been widely used in the primary coolant of PWR nuclear power plants. This study explored its effect water fusion reactors. research uses International Thermonuclear Experimental Reactor (ITER) water-cooled experimental simulation circuit, with Fe3O4 particles as corrosion products. deposition thickness on wall stainless steel tube at temperatures from 80 °C to 150 was measured by a non-destructive online magnetic measurement. results show that significant...