Miao He

ORCID: 0000-0002-2095-9281
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About
Contact & Profiles
Research Areas
  • Advanced biosensing and bioanalysis techniques
  • Biosensors and Analytical Detection
  • bioluminescence and chemiluminescence research
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Toxic Organic Pollutants Impact
  • Viral gastroenteritis research and epidemiology
  • Analytical chemistry methods development
  • Aquatic Ecosystems and Phytoplankton Dynamics
  • Marine and coastal ecosystems
  • Pesticide Residue Analysis and Safety
  • Water Quality Monitoring and Analysis
  • Microbial Community Ecology and Physiology
  • Water Treatment and Disinfection
  • Fecal contamination and water quality
  • Effects and risks of endocrine disrupting chemicals
  • Air Quality and Health Impacts
  • Electrochemical Analysis and Applications
  • Constructed Wetlands for Wastewater Treatment
  • Advanced Biosensing Techniques and Applications
  • Analytical Chemistry and Sensors
  • Molecular Junctions and Nanostructures
  • Antibiotic Resistance in Bacteria
  • Water Quality Monitoring Technologies
  • Atmospheric chemistry and aerosols
  • Marine Toxins and Detection Methods

Tsinghua University
2013-2023

Yulin University
2023

Beijing Institute of Mathematical Sciences and Applications
2023

University of Rochester
2023

Chengdu University
2023

Dali University
2023

State Key Joint Laboratory of Environment Simulation and Pollution Control
2011-2022

Yanbian University
2010-2022

Chinese National Engineering Research Center for Control and Treatment of Heavy Metal Pollution
2022

Nanjing Tech University
2018-2021

The greater abundances of antibiotic resistance genes (ARGs) in point-of-use tap and reclaimed water than that freshly treated raise the question whether residual disinfectants distribution systems facilitate spread ARGs. This study investigated three widely used (free chlorine, chloramine, hydrogen peroxide) on promoting ARGs transfer within Escherichia coli strains across genera from to Salmonella typhimurium. results demonstrated subinhibitory concentrations (lower minimum inhibitory...

10.1021/acs.est.6b03132 article EN Environmental Science & Technology 2016-12-05

The spread of antibiotic resistance represents a global threat to public health, and has been traditionally attributed extensive uses in clinical agricultural applications. As result, researchers have mostly focused on clinically relevant high-level enriched by antibiotics above the minimal inhibitory concentrations (MICs). Here, we report that two common water disinfection byproducts (chlorite iodoacetic acid) had antibiotic-like effects led evolution resistant E. coli strains under both...

10.1021/acs.est.5b05113 article EN Environmental Science & Technology 2016-02-29

Overcoming the limitations of traditional analytical methods and developing technologies to continuously monitor environments produce a comprehensive picture potential endocrine-disrupting chemicals (EDCs) has been an ongoing challenge. Herein, we developed portable nuclear receptor (NR)-based biosensor within 90 min perform highly sensitive analyses broad range EDCs in environmental water samples. Based on specific binding fluorescence–labeled NRs with their ligands, receptors were attached...

10.1021/acs.est.2c01323 article EN Environmental Science & Technology 2022-09-21

Required routine monitoring of endocrine disrupting compounds (EDCs) in water samples, as posed by EPA Unregulated Contaminant Regulation (UCMR3), demands for cost-effective, reliable and sensitive EDC detection methods. This study reports a reusable evanescent wave aptamer-based biosensor rapid, highly selective 17β-estradiol, an that is frequently detected environmental samples. In this system, the capture molecular, β-estradiol 6-(O-carboxy-methyl)oxime-BSA, was covalently immobilized...

10.1021/es203624w article EN Environmental Science & Technology 2012-01-31

Based on the statistical analysis of operational energy consumption and its influential factors from data 599 Chinese WWTPs in 2006, it is noticed that most include treatment technology adopted, treated sewage amount, removed pollutants etc. Using conclusion above, this paper sets up an integrated system performance assessment for municipal wastewater plants. Combining with result on-spot research model simulation, calculating method benchmark value score 7 efficiency indicators grouped into...

10.2166/wst.2010.394 article EN Water Science & Technology 2010-09-01

This study reports a comparative and mechanistic genotoxicity assessment of four engineered nanomaterials (ENMs) across three species, including E. coli, yeast, human cells, with the aim to reveal distinct potential mechanisms among different their association physiochemical features. Both conventional phenotypic alkaline comet test newly developed quantitative toxicogenomics assay, that detects quantifies molecular level changes in regulation six DNA damage repair pathways, were employed....

10.1021/es503065q article EN publisher-specific-oa Environmental Science & Technology 2014-10-22

A fully integrated graphene field‐effect transistor (GFET) nanosensor utilizing a novel high‐κ solid‐gating geometry for practical biosensor with enhanced sensitivity is presented. Herein, an “in plane” gate supplying electrical field through 30 nm HfO 2 dielectric layer employed to eliminate the cumbrous external wire electrode in conventional liquid‐gate GFET nanosensors that undesirably limits device potential on‐site sensing applications. In addition advantage integration degree,...

10.1002/adfm.201602960 article EN Advanced Functional Materials 2016-09-15

Enhancing the dissolution, permeation and absorption of active components with low solubility poor permeability is crucial for maximizing therapeutic efficacy optimizing functionality. The objective this study to investigate potential natural polysaccharides as carriers improve biopharmaceutical properties components.In study, we employed four representative flavonoids in Astragali Radix, namely Calycosin-7-O-β-D-glucoside (CAG), Ononin (ON), Calycosin (CA) Formononetin (FMN), a...

10.2147/ijn.s434196 article EN cc-by-nc International Journal of Nanomedicine 2023-11-01

Simple yet ultrasensitive and accurate quantification of a variety analytical targets by virtue universal sensing device holds promise to revolutionize environmental monitoring, medical diagnostics, food safety. Here, we propose novel optical surface plasmon resonance (SPR) system in which the frequency-shifted light different polarizations returned laser cavity stimulate heterodyne feedback interferometry (LHFI), hence amplifying reflectivity change caused refractive index (RI) variations...

10.1021/acs.est.3c01328 article EN Environmental Science & Technology 2023-05-18

This paper proposed a compact and portable planar waveguide evanescent wave immunosensor (EWI) for highly sensitive detection of BPA. The incident light is coupled into the chip via beveled angle through undergoing total internal reflection, where field forms excites binding fluorophore-tagged antibodies on surface. Typical calibration curves obtained BPA has limits 0.03 μg/L. Linear response ranged from 0.124 μg/L–9.60 μg/L with 50% inhibition concentration 1.09 ± 0.25 regeneration optical...

10.1038/srep04572 article EN cc-by-nc-sa Scientific Reports 2014-04-04

Bisphenol A (BPA) is a known endocrine disruptor and one of the most serious environmental contaminants, often present at low levels in various water sources.

10.1039/c4em00046c article EN Environmental Science Processes & Impacts 2014-01-01

Phthalic acid esters (PAEs) are ubiquitous in the environment, and some of them recognized as endocrine disruptors that cause concerns on ecosystem functioning public health. Due to diversity PAEs there is a vital need detect total concentration timely low-cost way. To fulfill this requirement, it highly desired obtain group-specific PAE binders specific basic skeleton. In study, for first time we have identified PAE-binding aptamers via rationally designed target immobilization. The two...

10.1021/acs.analchem.6b04808 article EN Analytical Chemistry 2017-04-17
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