A5075026770- Diet and metabolism studies
- Fatty Acid Research and Health
- Gut microbiota and health
- Diet, Metabolism, and Disease
- Sphingolipid Metabolism and Signaling
- Nutritional Studies and Diet
- Probiotics and Fermented Foods
- Liver Disease Diagnosis and Treatment
- Drug Transport and Resistance Mechanisms
- Dietary Effects on Health
- Cholesterol and Lipid Metabolism
- Nutrition, Genetics, and Disease
- Food composition and properties
- Psychosomatic Disorders and Their Treatments
- Adipose Tissue and Metabolism
- Proteins in Food Systems
- Peroxisome Proliferator-Activated Receptors
- Lipid metabolism and biosynthesis
- Ion Transport and Channel Regulation
- Digestive system and related health
- Endoplasmic Reticulum Stress and Disease
- Helicobacter pylori-related gastroenterology studies
- Tryptophan and brain disorders
- Adipokines, Inflammation, and Metabolic Diseases
- Phytoestrogen effects and research
Lallemand (France)
2024
Lallemand (Canada)
2024
Université Claude Bernard Lyon 1
2019-2023
Inserm
2019-2023
Laboratoire CarMeN
2019-2023
Université Laval
2015-2022
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2020-2021
Institut National des Sciences Appliquées de Lyon
2019-2021
Université de Bordeaux
2015-2018
Montreal Heart Institute
2015-2018
Objective The consumption of fruits is strongly associated with better health and higher bacterial diversity in the gut microbiota (GM). Camu camu ( Myrciaria dubia ) an Amazonian fruit a unique phytochemical profile, strong antioxidant potential purported anti-inflammatory potential. Design By using metabolic tests coupled 16S rRNA gene-based taxonomic profiling faecal microbial transplantation (FMT), we have assessed effect crude extract (CC) on obesity immunometabolic disorders high...
Objective To investigate whether milk polar lipids (PL) impact human intestinal lipid absorption, metabolism, microbiota and associated markers of cardiometabolic health. Design A double-blind, randomised controlled 4-week study involving 58 postmenopausal women was used to assess the chronic effects PL consumption (0, 3 or 5 g-PL/day) on metabolism gut microbiota. The acute absorption cholesterol were assessed in a crossover using tracers ileostomy patients. Results Over 4 weeks,...
Given the growing evidence that gut dysfunction, including changes in microbiota composition, plays a critical role development of inflammation and metabolic diseases, identification novel probiotic bacteria with immunometabolic properties has recently attracted more attention. Herein, bacterial strains were first isolated from dairy products human feces then screened vitro for their immunomodulatory activity. Five selected further analyzed vivo, using mouse model diet-induced obesity....
BACKGROUNDHigh circulating levels of ceramides (Cer) and sphingomyelins (SM) are associated with cardiometabolic diseases. The consumption whole fat dairy products, naturally containing such polar lipids (PL), is health benefits, but the impact on sphingolipidome remains unknown.METHODSIn a 4-week randomized controlled trial, 58 postmenopausal women daily consumed milk PL-enriched cream cheese (0, 3, or 5 g PL). Postprandial metabolic explorations were performed before after supplementation....
Supplementation with probiotics has emerged as a promising therapeutic tool to manage metabolic diseases. We investigated the effects of mix Bifidobacterium animalis subsp. lactis LA804 and Lactobacillus gasseri LA806 on high-fat (HF) diet -induced disease in mice. probiotic HF diet-fed mice (HF-Pr2) reduced weight fat mass gains, decreased hepatic lipid accumulation, lowered plasma triglyceride peak during an oral tolerance test. At molecular level, protected against HF-induced rise mRNA...
Abstract We compared endogenous ω-3 PUFA production to supplementation for improving obesity-related metabolic dysfunction. Fat-1 transgenic mice, who endogenously convert exogenous ω-6 PUFA, and wild-type littermates were fed a high-fat diet daily dose of either or PUFA-rich oil 12 wk. The improved glucose intolerance insulin resistance but not hepatic steatosis. Conversely, fully prevented steatosis failed improve resistance. Both models increased levels PUFA-containing 2-monoacylglycerol...
The metabolic impact of dietary lipids needs to be considered beyond the fatty acid profile and energetic value such lipids. Fatty acids are building blocks different lipid molecules, including triacylglycerols phospholipids, which organized within various supramolecular structures as emulsion droplets. These can also naturally present or incorporated a posteriori in food matrices. Gut health its barrier function microbiota is now recognized major player cardiometabolic health. Even if more...
Scope The gut microbiota plays a role in fat accumulation and energy homeostasis. Therefore, probiotic supplementation may improve metabolic parameters control body weight. Methods results In this study, mice are fed either high‐fat diet (HFD) or an HFD supplemented with oral gavage of mixture three strains, Bifidobacterium lactis Lafti B94, Lactobacillus plantarum HA‐119, helveticus L10 for 7 weeks. It finds that modulates weight gain, food efficiency, caused by the HFD. This mix prevents...
Nutritional strategies can play a major role in the management of cholesterolemia, notably postmenopausal women at risk CVD. Interest has recently grown on potential health benefits milk polar lipids (MPL). We showed that isolipidic enrichment diet with MPL improved several lipid CV factors but underlying mechanisms remained unclear. hypothesized reduce intestinal cholesterol absorption humans. performed double-blind randomized controlled trial 58 fasting HDL-cholesterol < 1.6 mM. They were...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)