A5085233831- Plant tissue culture and regeneration
- Phytochemicals and Antioxidant Activities
- Gut microbiota and health
- Berry genetics and cultivation research
- Growth and nutrition in plants
- Plant Physiology and Cultivation Studies
- Turfgrass Adaptation and Management
- Plant nutrient uptake and metabolism
- Photosynthetic Processes and Mechanisms
- Diet and metabolism studies
- Plant Pathogens and Fungal Diseases
- Antioxidant Activity and Oxidative Stress
- Seedling growth and survival studies
- Potato Plant Research
- Plant Stress Responses and Tolerance
- Horticultural and Viticultural Research
- Tea Polyphenols and Effects
- Probiotics and Fermented Foods
- Postharvest Quality and Shelf Life Management
- Light effects on plants
- Biochemical Analysis and Sensing Techniques
- Plant Genetic and Mutation Studies
- Transgenic Plants and Applications
- Microbial Metabolites in Food Biotechnology
- Mycorrhizal Fungi and Plant Interactions
Université Laval
2016-2025
Université du Québec en Abitibi-Témiscamingue
2024
Universitat Rovira i Virgili
2023
NutriNeuro
2018
Nova Scotia Department of Agriculture
2011
Agriculture and Agri-Food Canada
2010-2011
The Ohio State University
2007
Centro de Ingeniería Genética y Biotecnología
2003
Cairo University
2000
University of Tennessee at Knoxville
2000
<h3>Objective</h3> The increasing prevalence of obesity and type 2 diabetes (T2D) demonstrates the failure conventional treatments to curb these diseases. gut microbiota has been put forward as a key player in pathophysiology diet-induced T2D. Importantly, cranberry (<i>Vaccinium macrocarpon</i> Aiton) is associated with number beneficial health effects. We aimed investigate metabolic impact extract (CE) on high fat/high sucrose (HFHS)-fed mice determine whether its consequent antidiabetic...
Objective The consumption of fruits is strongly associated with better health and higher bacterial diversity in the gut microbiota (GM). Camu camu ( Myrciaria dubia ) an Amazonian fruit a unique phytochemical profile, strong antioxidant potential purported anti-inflammatory potential. Design By using metabolic tests coupled 16S rRNA gene-based taxonomic profiling faecal microbial transplantation (FMT), we have assessed effect crude extract (CC) on obesity immunometabolic disorders high...
Abstract Cranberry is associated with multiple health benefits, which are mostly attributed to its high content of (poly)phenols, particularly flavan-3-ols. However, clinical trials attempting demonstrate these positive effects have yielded heterogeneous results, partly due the inter-individual variability gut microbiota interaction molecules. In fact, several studies demonstrated ability molecules modulate in animal and vitro models, but there a scarcity information human subjects....
Previous studies have reported that polyphenol-rich extracts from various sources can prevent obesity and associated gastro-hepatic metabolic disorders in diet-induced obese (DIO) mice. However, whether such reverse obesity-linked alterations remains unknown. In the present study, we aimed to investigate potential of a extract cranberry (CE) DIO-mice.Mice were pre-fed either Chow or High Fat-High Sucrose (HFHS) diet for 13 weeks induce then treated with CE (200 mg/kg, + CE, HFHS CE) vehicle...
Abstract Plant-derived foods rich in polyphenols are associated with several cardiometabolic health benefits, such as reduced postprandial hyperglycaemia. However, their impact on whole-body insulin sensitivity using the hyperinsulinaemic-euglycaemic clamp technique remains under-studied. We aimed to determine effects of strawberry and cranberry (SCP) sensitivity, glucose tolerance, secretion, lipid profile, inflammation oxidative stress markers free-living insulin-resistant overweight or...
The gut and its bacterial colonizers are now well characterized as key players in whole-body metabolism, opening new avenues of research generating great expectation for treatments against obesity cardiometabolic complications. As diet is the main environmental factor affecting microbiota, it has been suggested that fruits vegetables, whose consumption strongly associated with a healthy lifestyle, may carry phytochemicals could help maintain intestinal homeostasis metabolic health. We...
Since gastrointestinal mucosa is constantly exposed to reactive oxygen species from various sources, the presence of antioxidants may contribute body's natural defenses against inflammatory diseases. Hypothesis To define polyphenols extracted dried apple peels (DAPP) and determine their antioxidant anti-inflammatory potential in intestine. Caco-2/15 cells were used study role DAPP preventive actions oxidative stress (OxS) inflammation induced by iron-ascorbate (Fe/Asc) lipopolysaccharide...
Berries are rich in polyphenols and plant cell wall polysaccharides (fibres), including cellulose, hemicellulose, arabinans arabino-xyloglucans pectin. Most of fibres known to be poorly absorbed the small intestine reach colon where they interact with gut microbiota, conferring health benefits host. This study assessed contribution polyphenol-rich whole cranberry blueberry fruit powders (CP BP), that their fibrous fractions (CF BF) on modulating microbial functional profile influencing...
Cranberry fruit has been reported to have high antioxidant effectiveness that is potentially linked its richness in diversified polyphenolic content. The aim of the present study was determine role cranberry fractions oxidative stress (OxS), inflammation and mitochondrial functions using intestinal Caco-2/15 cells. combination HPLC UltraPerformance LC®-tandem quadrupole (UPLC-TQD) techniques allowed us characterize profile low, medium molecular mass compounds extracts. fraction enriched with...
The chemical composition and in vitro antioxidant capacity (AC) of the two most commercialized species jaboticaba, Sabará (Myrciaria jaboticaba) Paulista cauliflora), were compared different fruit parts (skin, pulp seeds) at ripening stages. Both presented similar mineral centesimal compositions, found to be rich sources Mn (1.8–2.7 mg/100 g DW) Cu (1.0 DW). Except for anthocyanins, phenolic concentrations greater amounts than Paulista. Ellagic acid derivatives (EA) contents varied according...
Blueberries are a rich source of polyphenols, widely studied for the prevention or attenuation metabolic diseases. However, health contribution and mechanisms action polyphenols depend on their type structure. Here, we evaluated effects wild blueberry polyphenolic extract (WBE) (Vaccinium angustifolium Aiton) cardiometabolic parameters, gut microbiota composition epithelium histology high-fat high-sucrose (HFHS) diet-induced obese mice determined which constitutive fractions (BPF) was...
Polyphenols are promising nutritional bioactives exhibiting beneficial effect on age-related cognitive decline. This study evaluated the of a polyphenol-rich extract from grape and blueberry (PEGB) memory healthy elderly subjects (60–70 years-old). A bicentric, randomized, double-blind, placebo-controlled trial was conducted with 215 volunteers receiving 600 mg/day PEGB (containing 258 mg flavonoids) or placebo for 6 months. The primary outcome CANTAB Paired Associate Learning (PAL),...
Blueberry consumption can prevent obesity-linked metabolic diseases, and it has been proposed that the polyphenol content of blueberries may contribute to these effects. Polyphenols have shown favorably impact health, but role specific classes whether gut microbiota is linked effects remain unclear. We aimed evaluate whole blueberry powder polyphenols on development obesity insulin resistance determine potential microbes in by using fecal transplantation (FMT). Sixty-eight C57BL/6 male mice...
The consumption of plant-based bioactive compounds modulates the gut microbiota and interacts with innate adaptive immune responses associated metabolic disorders. present study aimed to evaluate effect cranberry polyphenols (CP), rich in flavonoids, agavins (AG), a highly branched agave-derived neo-fructans, on cardiometabolic response, composition, endotoxemia, mucosal immunomodulation C57BL6 male mice fed an obesogenic high-fat high-sucrose (HFHS) diet for 9 weeks. Interestingly,...