A5026754214- Gestational Diabetes Research and Management
- Diabetes Management and Research
- Adipose Tissue and Metabolism
- Diabetes Treatment and Management
- Metabolism, Diabetes, and Cancer
- Diet and metabolism studies
- Adipokines, Inflammation, and Metabolic Diseases
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Birth, Development, and Health
- Obesity, Physical Activity, Diet
- Bariatric Surgery and Outcomes
- Pancreatic function and diabetes
- Regulation of Appetite and Obesity
- Eating Disorders and Behaviors
- Diabetes and associated disorders
- Genetic Associations and Epidemiology
- Pharmacology and Obesity Treatment
- Pregnancy and preeclampsia studies
- Hormonal Regulation and Hypertension
- Muscle metabolism and nutrition
- Nutritional Studies and Diet
- Health and Lifestyle Studies
- Liver Disease Diagnosis and Treatment
- Nutrition and Health in Aging
- Diet, Metabolism, and Disease
Université Laval
2015-2024
Wilfrid Laurier University
2009-2020
Centre hospitalier universitaire de Québec
2009-2019
Centre hospitalier de l'Université Laval
2004-2015
Diabetes Québec
2012-2014
Quebec Research and Development Centre
2014
Royal Victoria Hospital
2014
McGill University Health Centre
2014
Université du Québec à Montréal
2014
Genomics (United Kingdom)
2011-2012
OBJECTIVE—To determine the effect of a 20-week endurance training program in healthy, previously sedentary participants on measures derived from an intravenous glucose tolerance test (IVGTT). RESEARCH DESIGN AND METHODS—An IVGTT was performed before and after standardized 316 women 280 men (173 blacks 423 whites). Participants exercised cycle ergometers 3 days per week for 60 sessions. The exercise intensity progressively increased 55% Vo2max 30 min session to 75% 50 session. RESULTS—Mean...
Abstract This paper presents the eleventh update of human obesity gene map, which incorporates published results up to end October 2004. Evidence from single‐gene mutation cases, Mendelian disorders exhibiting as a clinical feature, transgenic and knockout murine models relevant obesity, quantitative trait loci (QTLs) animal cross‐breeding experiments, association studies with candidate genes, linkages genome scans is reviewed. As 2004, 173 cases due mutations in 10 different genes have been...
Aim: Recent studies indicate that type 2 diabetes is associated with an increased secretion of both hepatic and intestinal lipoproteins, leading to the accumulation atherogenic triglyceride (TG)-rich lipoproteins. Sitagliptin a selective inhibitor dipeptidyl peptidase-4 has been shown reduce fasting postprandial glucose levels in patients presumably through incretin hormone-mediated improvements islet function. The objective present study examine effects treatment sitagliptin on lipid...
Abstract Plant-derived foods rich in polyphenols are associated with several cardiometabolic health benefits, such as reduced postprandial hyperglycaemia. However, their impact on whole-body insulin sensitivity using the hyperinsulinaemic-euglycaemic clamp technique remains under-studied. We aimed to determine effects of strawberry and cranberry (SCP) sensitivity, glucose tolerance, secretion, lipid profile, inflammation oxidative stress markers free-living insulin-resistant overweight or...
To determine whether vitamin D3 supplementation improves insulin sensitivity, using the hyperinsulinemic-euglycemic clamp.This single-centre, double-blind, placebo-controlled trial randomised 96 participants at high risk of diabetes or with newly diagnosed type 2 to 5000 IU daily placebo for 6 months.We assessed baseline and months: (1) primary aim: peripheral sensitivity (M-value a 2-h clamp); (2) secondary aims: other (HOMA2%S, Matsuda) secretion (insulinogenic index, C-peptide area under...
Recent studies have shown that high interleukin-6 (IL-6) secretion may aggravate insulin resistance in pregnancy and participate the pathogenesis of gestational diabetes mellitus (GDM). The aim this study was to determine whether presence GDM is associated with elevated IL-6 concentrations association remains after delivery, independent body mass index.Longitudinal study.Hospital-based.Forty-seven women were screened for a 75g oral glucose tolerance test at 26.1±3.7 weeks following Canadian...
The objective of the present study was to test whether a brown seaweed extract rich in polyphenols combined with low-calorie diet would induce additional weight loss and improve blood glucose homeostasis association metabolic inflammatory response overweight/obese prediabetic subjects. Fifty-six overweight/obese, dysglycemic, insulin-resistant men women completed randomized, placebo-controlled, double-blind, parallel clinical trial. Subjects were administrated 500 mg/d either or placebo...
Diet during pregnancy greatly impacts health outcomes. This study aims to measure changes in dietary intakes throughout trimesters and assess pregnant women’s comparison with current Canadian nutritional recommendations. Seventy-nine women were recruited completed, within each trimester, three Web-based 24-h recalls one Web questionnaire on supplement use. Dietary from food, without supplements, compared recommendations pregnancy. Energy macronutrient remained stable A majority of exceeded...
In the present multicentre, open‐label, prospective, phase III study, we evaluated real‐world effectiveness and ease of use nasal glucagon (NG) in treatment moderate/severe hypoglycaemic events (HEs) adults with type 1 diabetes (T1D). Patients caregivers were taught how to NG (3 mg) treat HEs, record time taken awaken or return normal status, measure blood glucose (BG) levels over time. Questionnaires used collect information about adverse NG. efficacy analysis population, 69 patients...
We recently reported that a genomic region close to the leptin locus was linked fasting insulin response exercise training in nondiabetic white subjects. tested hypothesis common exonic variants (LEP) and receptor (LEPR) genes modify effects of regular physical activity on glucose homeostasis whites (n = 397) blacks 143). In whites, increased sensitivity index (P 0.041) disposition 0.046) LEPR 109R allele carriers but not K109K homozygotes, disappearance more R109R homozygotes than K109...
Few studies have investigated whether favorable effects of lactation persist after weaning and protect women with prior gestational diabetes mellitus (GDM) against later development insulin resistance secretion defects.To investigate the impact duration on glucose response among GDM.The study group comprised 144 a history GDM between 2003 2010. Plasma concentrations were obtained from 75 g oral tolerance test (OGTT). Total (exclusive breastfeeding breast bottle-feeding) for all infants was...