Mercedes Rigla

ORCID: 0000-0002-6691-4871
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About
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Research Areas
  • Diabetes Management and Research
  • Pancreatic function and diabetes
  • Mobile Health and mHealth Applications
  • Diabetes and associated disorders
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Diabetes Treatment and Management
  • Bariatric Surgery and Outcomes
  • Pituitary Gland Disorders and Treatments
  • Adrenal Hormones and Disorders
  • Cardiovascular Disease and Adiposity
  • Adipokines, Inflammation, and Metabolic Diseases
  • Gestational Diabetes Research and Management
  • Genetic Syndromes and Imprinting
  • Adrenal and Paraganglionic Tumors
  • Artificial Intelligence in Healthcare
  • Thyroid Disorders and Treatments
  • Retinal Imaging and Analysis
  • Neuroendocrine Tumor Research Advances
  • Metabolism, Diabetes, and Cancer
  • Healthcare Systems and Technology
  • Lipoproteins and Cardiovascular Health
  • Wireless Body Area Networks
  • Hormonal Regulation and Hypertension
  • Chronic Kidney Disease and Diabetes
  • Psoriasis: Treatment and Pathogenesis

Universitat Autònoma de Barcelona
2015-2024

Corporació Sanitària Parc Taulí
2009-2024

Institute of Research and Innovation Parc Tauli
2017-2024

Deleted Institution
2011-2023

Instituto de Salud Carlos III
2008-2021

Institut thématique Immunologie, inflammation, infectiologie et microbiologie
2021

Pfizer (France)
2021

Centro de Investigación Biomédica en Red
2021

Universidad de Alcalá
2021

The University of Melbourne
2016

Background and Aims: Continuous glucose monitoring (CGM) devices could be useful for real-time management of diabetes therapy. In particular, CGM information used in real time to predict future levels order prevent hypo-/hyperglycemic events. This article proposes a new online method predicting concentration from data. Methods: The predictor is implemented with an artificial neural network model (NNM). inputs the NNM are values provided by sensor during preceding 20 min, while output...

10.1089/dia.2009.0076 article EN Diabetes Technology & Therapeutics 2010-01-01
Matthias von Herrath Stephen C. Bain Bruce W. Bode Jesper O. Clausen Ken Coppieters and 95 more Leyla Gaysina Janusz Gumprecht Troels Krarup Hansen Chantal Mathieu Cristóbal Morales Ofri Mosenzon Stine Segel George Tsoukas Thomas R. Pieber Bernhard Ludvik Rudolf Prager Bernhard Paulweber Christoph Ebenbichler Bart Keymeulen Christophe De Block Loren D. Grossman Robyn L. Houlden Patrice Perron Thomas Ransom Peter Senior S. John Weisnagel Vincent Woo R Dumas David Thompson Tina Vilsbøll Jeppe Gram Claus Bogh Juhl Janne Hukkanen Jorma Lahtela Leo Niskanen Donal O’Shea Timothy O’Brien Séamus Sreenan Julio Wainstein Moshe Phillip Hilla Knobler Francesco Dotta Pier Marco Piatti Roberto Trevisan Agostino Gnasso Hanne L. Gulseth John Cooper Ewa Pańkowska Monika Łukaszewicz Bogumił Wolnik Isabel Manita Olinda Marques Cristina Roque Rosa Maria Príncipe Celestino Neves Susana Heitor L. A. Ruyatkina I. V. Dvoryashina Gulnar Vagapova Lidiya Belousova M. Sergeeva-Kondrachenko А.Б. Песков Elena Frolova Albina Golovach М. А. Куницына N Krasnopeeva Irina Ipatko Carmen de la Cuesta Benjumea Francisco J. Tinahones Mercedes Rigla Juan Francisco Merino-Torres Luis Alberto Gómez Mercè Fernández Rafael Simó Mikael Rydén Johan Jendle Karin Filipsson Björn Eliasson Boris Mankovsky Iurii Lymar Liubov Sokolova Galyna Myshanych Tetiana Zlova М.V. Vlasenkо Petro Kuskalo - Hamish Courtney Colin Dayan Patrick English Simon Heller A.B. Johnson Sunil Nair Richard David Leslie Parth Narendran Nick Oliver Shenaz Ramtoola J. H. F. Shaw Adie Viljoen Amer Al‐Karadsheh Jean M. Dostou Sumana Gangi

10.1016/s2213-8587(21)00019-x article EN The Lancet Diabetes & Endocrinology 2021-03-01

Surgery is the treatment of choice for many pituitary tumors; function may suffer after operation, but relief pressure on normal also favor postoperative recovery hypopituitarism. The aim this study was to investigate frequency new appearance and hypopituitarism neurosurgery try identify features associated with it. Pre- anterior functions were investigated in 234 patients adenomas (56 nonfunctioning, 71 PRL-secreting, 66 GH-secreting, 39 ACTH-secreting, 1 LH/FSH-secreting, TSH-secreting...

10.1210/jcem.84.10.6019 article EN The Journal of Clinical Endocrinology & Metabolism 1999-10-01

In the past decade diabetes management has been transformed by addition of continuous glucose monitoring and insulin pump data. More recently, a wide variety functions physiologic variables, such as heart rate, hours sleep, number steps walked movement, have available through wristbands or watches. New data, hydration, geolocation, barometric pressure, among others, will be incorporated in future. All these parameters, when analyzed, can helpful for patients doctors’ decision support....

10.1177/1932296817710475 article EN Journal of Diabetes Science and Technology 2017-05-25

Gestational diabetes (GDM) burden has been increasing progressively over the past years. Knowing that intrauterine exposure to maternal confers high risk for macrosomia as well future type 2 and obesity of offspring, health care organizations try provide effective control in spite limited resources. Artificial-intelligence-augmented telemedicine proposed a helpful tool facilitate an efficient widespread medical assistance GDM. The aim study we present was test feasibility acceptance mobile...

10.1177/1932296817704442 article EN Journal of Diabetes Science and Technology 2017-04-18

We describe our experience in the remote management of women with gestational diabetes mellitus during COVID-19 pandemic. used a mobile phone application artificial intelligence that automatically classifies and analyses data (ketonuria, diet transgressions, blood glucose values), making adjustment recommendations regarding or insulin treatment.

10.1016/j.diabres.2020.108396 article EN other-oa Diabetes Research and Clinical Practice 2020-09-03

Tumor necrosis factor-alpha (TNF-alpha) is increasingly recognized as a key component in the development of insulin resistance and increased blood pressure. In sample 368 individuals, ratio soluble TNF-alpha receptors (sTNFR2/sTNFR1) correlated positively with systolic diastolic pressure (P < 0.01). This was significantly greater type 2 diabetic subjects (DM-2) than 1 patients control nondiabetic 0.00001). The receptor (TNFR1) density peripheral monocytes similar DM-2 subjects. After phorbol...

10.1152/ajpendo.00444.2001 article EN AJP Endocrinology and Metabolism 2002-04-01

Biomedical engineering research efforts have accomplished another level of a "technological solution" for diabetes: an artificial pancreas to be used by patients and supervised healthcare professionals at any time place. Reliability continuous glucose monitoring, availability real-time programmable insulin pumps, validation safe efficient control algorithms are critical components achieving that goal. Nevertheless, the development integration these new technologies within telemedicine system...

10.1109/titb.2007.902162 article EN IEEE Transactions on Information Technology in Biomedicine 2008-07-01

Previous studies have shown increased prevalence of metabolic syndrome in patients with psoriasis.To characterize the anthropometric and profile Spanish moderate to severe psoriasis compared controls without matched for gender, age body mass index (BMI), evaluate impact narrowband ultraviolet B (NB-UVB) therapy on patient profiles.Baseline waist circumference, fat composition, lipid, carbohydrate calcium metabolism profile, inflammation markers, homocysteine, vitamins D, B(6) B(12) folic...

10.1111/j.1365-2133.2012.10883.x article EN British Journal of Dermatology 2012-02-07

Context Prader-Willi syndrome (PWS) is characterized by severe hyperphagia. Brain-derived neurotrophic factor (BDNF) and leptin are reciprocally involved in energy homeostasis. Objectives To analyze the role of BDNF satiety genetic subtypes PWS. Design Experimental study. Setting University hospital. Subjects 90 adults: 30 PWS patients; age-sex-BMI-matched obese controls; age-sex-matched lean controls. Interventions ingested a liquid meal after fasting ≥10 hours. Main Outcome Measures Leptin...

10.1371/journal.pone.0163468 article EN cc-by PLoS ONE 2016-09-29

OBJECTIVE Early worsening of diabetic retinopathy (EWDR) due to the rapid decrease blood glucose levels is a concern in diabetes treatment. The aim current study evaluate whether this an important issue subjects with type 2 mild or moderate nonproliferative DR (NPDR), who represent vast majority attended primary care. RESEARCH DESIGN AND METHODS This retrospective nested case-control and previous NPDR. Using SIDIAP (“Sistema d'informació pel Desenvolupament de la Recerca Atenció Primària”)...

10.2337/dc22-2521 article EN Diabetes Care 2023-07-10

<h3>Background</h3> Data on the prevalence of dyslipidemia in type 1 diabetes mellitus are scarce and based total triglyceride cholesterol concentrations alone. <h3>Objective</h3> To assess effect glycemic optimization low-density lipoprotein (LDL-C) requiring intervention patients with diabetes. <h3>Patients</h3> A 334 adults 803 nondiabetic control subjects. <h3>Methods</h3> Levels glycosylated hemoglobin, cholesterol, triglyceride, high-density (HDL-C), LDL-C were assessed at baseline...

10.1001/archinte.160.18.2756 article EN Archives of Internal Medicine 2000-10-09

The effect of insulin therapy on low-density lipoprotein (LDL) oxidizability, proportion electronegative LDL [LDL(−)] and composition was studied in 33 type 2 diabetic patients. Before glycemic control improvement, subjects presented higher triglyceride very cholesterol lower high-density than 25 healthy matched subjects. Furthermore, their more susceptible to oxidation (lag phase 45.9 ± 5.4 min vs. 49.7 7.6 min, P < 0.05), contained a LDL(−) (19.0 8.7% 14.3 5.5%, enriched depleted...

10.1210/jcem.86.7.7692 article EN The Journal of Clinical Endocrinology & Metabolism 2001-07-01

Recent advances in information and communication technology allow the design testing of new models diabetes management, which are able to provide assistance patients regardless their distance from health care providers. The M2DM project, funded by European Commission, has specific aim investigate potential novel telemedicine services management. A multi-access system based on integration Web access, telephone access through interactive voice response systems, use palmtops smart modems for...

10.1089/152091503322250640 article EN Diabetes Technology & Therapeutics 2003-08-01

The risks associated with gestational diabetes (GD) can be reduced an active treatment able to improve glycemic control. Advances in mobile health provide new patient-centric models for GD create personalized care services, increase patient independence and patients' self-management capabilities, potentially their compliance. In these models, decision-support functions play essential role. telemedicine system MobiGuide provides medical decision support patients that is based on computerized...

10.1177/1932296814526492 article EN Journal of Diabetes Science and Technology 2014-03-01

Background: In type 1 diabetes mellitus (T1DM), patients play an active role in their own care and need to have the knowledge adapt decisions daily living conditions. Artificial intelligence applications can help people with decision making allow them react at time scales shorter than scheduled face-to-face visits. This work presents a support system (DSS), based on glucose prediction, assist mobile environment. Methods: The system’s impact therapeutic corrective actions has been evaluated...

10.1177/1932296818761457 article EN Journal of Diabetes Science and Technology 2018-03-01
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