- Semantic Web and Ontologies
- Electronic Health Records Systems
- Clinical practice guidelines implementation
- Business Process Modeling and Analysis
- Biomedical Text Mining and Ontologies
- Systemic Lupus Erythematosus Research
- Stroke Rehabilitation and Recovery
- Renal Diseases and Glomerulopathies
- Health Systems, Economic Evaluations, Quality of Life
- Mobile Health and mHealth Applications
- Acute Ischemic Stroke Management
- Asthma and respiratory diseases
- Bayesian Modeling and Causal Inference
- Head and Neck Cancer Studies
- Allergic Rhinitis and Sensitization
- Context-Aware Activity Recognition Systems
- Radiomics and Machine Learning in Medical Imaging
- Healthcare Systems and Technology
- Digital Mental Health Interventions
- AI-based Problem Solving and Planning
- Telemedicine and Telehealth Implementation
- Dementia and Cognitive Impairment Research
- Machine Learning in Healthcare
- Urinary Bladder and Prostate Research
- Service-Oriented Architecture and Web Services
University of Pavia
2015-2024
Istituti Clinici Scientifici Maugeri
2023
Ibero American University
2019
Istituti di Ricovero e Cura a Carattere Scientifico
1993-2016
Università degli Studi del Piemonte Orientale “Amedeo Avogadro”
2015
Bocconi University
2015
Fondazione Salvatore Maugeri
2015
Ospedale Maggiore
1998-2013
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2012-2013
Antwerp University Hospital
2009
Many groups are developing computer-interpretable clinical guidelines (CIGs) for use during encounters. CIGs "Task-Network Models" representation but differ in their approaches to addressing particular modeling challenges. We have studied similarities and differences between order identify issues that must be resolved before a consensus on set of common components can developed.We compared six models: Asbru, EON, GLIF, GUIDE, PRODIGY, PROforma. Collaborators from created these models...
Abstract Background Monitoring body kinematics has fundamental relevance in several biological and technical disciplines. In particular the possibility to exactly know posture may furnish a main aid rehabilitation topics. present work an innovative unobtrusive garment able detect movement of upper limb been introduced, with care its application post stroke field by describing integration prototype healthcare service. Methods This paper deals design, development implementation sensing...
Objectives: To evaluate the role of immunological tests for monitoring lupus nephritis (LN) activity. Methods: C3, C4, anti-dsDNA and anti-C1q antibodies were prospectively performed over 6 years in 228 patients with LN. Results: In membranous LN only differentiated proteinuric flares from quiescent disease (p = 0.02). However, this group 46% occurred a normal value versus 20% proliferative antiphospholipid (APL), 33% levels 14.5% that APL-negative LN, showed slightly better sensitivity...
Background. Few data are available about the very long-term outcome of patients with proliferative lupus nephritis.
Objectives To evaluate changes in demographic, clinical and histological presentation, prognosis of lupus nephritis (LN) over time. Patients methods We studied a multicentre cohort 499 patients diagnosed with LN from 1970 to 2016. The 46-year follow-up was subdivided into three periods (P): P1 1970–1985, P2 1986–2001 P3 2002–2016, accordingly grouped based on the year diagnosis. Predictors patient renal survival were investigated by univariate multivariate proportional hazards Cox regression...
BackgroundFew data are available on allograft survival at 15 years, the impact and predictors of recurrence original disease in renal transplanted patients with IgA nephropathy (IgAN).
Short-term predictive endpoints of chronic kidney disease (CKD) are needed in lupus nephritis (LN). We tested response to therapy at 1 year.We considered patients with LN who underwent renal biopsy followed by induction between January 1970 and December 2016. was assessed using the International Society Nephrology/Renal Pathology (2003) criteria National Institute Health (NIH) activity chronicity index. The outcome CKD. Response defined according EULAR/European League Against...
IntroductionThe aim of this retrospective study on biopsy-proven lupus nephritis (LN) patients is to assess the probability sustained clinical remission (sCR) and investigate sCR effects disease flares impaired kidney function (IKF).MethodssCR was defined as clinical-SLEDAI-2K=0 eGFR>60ml/min/1.73m2 lasting≥1 year; IKF: eGFR<60ml/min/1.73m2 for>3 months. We analysed achieving maintaining sCR, yearly risk flare. Cox models were used identify predictors IKF with variables time-depending...
Although several studies have demonstrated the effectiveness of specialist Stroke Unit (SU) care stroke patients, there is still disagreement over how these units are best organized. We sought to clarify role continuous monitoring physiological parameters in acute ischemic stroke.We conducted a prospective study 268 first-ever patients admitted our Cerebrovascular Department and allocated, according availability beds, SU or (CU). Statistical analysis compared mortality outcome at discharge,...
A significant number of preventable cardiac deaths in infancy and childhood are due to long QT syndrome (LQTS) unrecognized neonatal congenital heart diseases (CHDs). Both carry a serious risk for avoidable mortality morbidity but effective treatments exist prevent lethal arrhythmias or allow early surgical correction before death irreversible damage. As an electrocardiogram (ECG) allows recognition LQTS some the CHDs that have escaped medical diagnosis, as also contributes sudden infant...
Background. Whether corticosteroid and immunosuppressive therapy may be safely withdrawn in patients with proliferative lupus nephritis is still unclear.