A5101557296- Liver Disease Diagnosis and Treatment
- Diet and metabolism studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiovascular Function and Risk Factors
- Cardiovascular Health and Disease Prevention
- Gastrointestinal motility and disorders
- Gout, Hyperuricemia, Uric Acid
- Cardiovascular Disease and Adiposity
- Gestational Diabetes Research and Management
- Lipoproteins and Cardiovascular Health
- Gastric Cancer Management and Outcomes
- Nutritional Studies and Diet
- Complementary and Alternative Medicine Studies
- Nutrition and Health in Aging
- Respiratory Support and Mechanisms
- Pregnancy and preeclampsia studies
- Thyroid Disorders and Treatments
- Cardiovascular Health and Risk Factors
- COVID-19 Clinical Research Studies
- Folate and B Vitamins Research
- Diet, Metabolism, and Disease
- Gut microbiota and health
- Health Promotion and Cardiovascular Prevention
- Cancer-related molecular mechanisms research
- Heart Failure Treatment and Management
Shanghai East Hospital
2016-2025
Jinan University
2023-2024
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
2024
Tongji University
2015-2024
Nanjing University of Chinese Medicine
2017-2022
First Affiliated Hospital of Wenzhou Medical University
2021
First Hospital of Jiaxing
2021
Wenzhou Medical University
2014-2021
Wenzhou City People's Hospital
2021
National Clinical Research Center for Digestive Diseases
2019
Abstract Background The SARS‐CoV‐2 pandemic is an ongoing global health emergency. aim of our study was to investigate the changes liver function and its clinical significance in COVID‐19 patients. Method This retrospective, single‐centre conducted on 115 confirmed cases Zhongnan hospital Wuhan University from 18 January 2020 22 February 2020. Liver related indexes were analysed evaluate relationship with disease progression Results Part patients presented varying degrees abnormality...
The American Heart Association (AHA) has recently introduced the concept of Cardiovascular-Kidney-Metabolic (CKM) syndrome, which is result an increasing emphasis on interplay metabolic, renal and cardiovascular diseases (CVD). Furthermore, there substantial evidence a correlation between triglyceride glucose-body mass index (TyG-BMI ) CVD as assessment insulin resistance (IR). However, it remains unknown whether this exists in population with CKM syndrome.
Abstract Obesity is usually considered to predispose atherosclerotic cardiovascular disease (ASCVD) but milder degrees of obesity or overweight may be protective in some elderly populations. We examined the relationships between general and abdominal indices with ASCVD its risk factors (aged ≥65 years) Shanghai community residents Among 3950 participants, 21.5% had ASCVD, 56.2% body mass index (BMI) ≥24 kg/m2, 50.1% high waist circumference (WC) 77.1% waist-to-height ratio (WHtR) ≥0.50. WHtR...
To compare the association of hypertension plus hyperuricemia with four insulin resistance surrogates, including glucose and triglycerides (TyG index), TyG index body mass (TyG-BMI), ratio divided by high-density lipoprotein cholesterol (TG/HDL-C) metabolic score for (METS-IR).
Abstract Background Mesenchymal stem cells (MSCs) hold a great promise for cell-based therapy in the field of regenerative medicine. In this study, we aimed to evaluate safety and efficacy intravenous infusion human umbilical cord-derived MSCs (HUC-MSCs) patients with aging frailty. Methods randomized, double-blind, placebo-controlled trial, participants diagnosed frailty were randomly assigned receive administrations HUC-MSCs or placebo. All serious adverse events AEs monitored treatment...
Rationale: Despite recent studies indicating a crucial role of ecto-5′-nucleotidase (CD73) on T cells in cardiac injury after ischemia/reperfusion, the involvement CD73 + regulatory (Tregs) repair post-myocardial infarction (MI) remains unclear.We sought to investigate contribution Tregs resolution inflammation and remodeling MI.Methods: Cardiac function, tissue injury, percentage injured hearts, purinergic signaling changes FoxP3 were analyzed permanent descending coronary artery...
COVID-19 patients often suffer from post-COVID-19 acute sequelae (PASC). Pulmonary fibrosis has the most significant long-term impact on respiratory health of patients, known as pulmonary (PC19-PF). PC19-PF can be caused by distress syndrome (ARDS) or COVID-19-induced pneumonia. Individuals who experience pneumonia symptoms (including cough, shortness breath, dyspnea exertion, and desaturation) for at least 12 weeks after diagnosis, almost all develop PC19-PF. Extracellular matrix molecules:...
Injuries are a growing public health concern in China, accounting for more than 30% of all Person Years Life Lost (PYLL) due to premature mortality. This study analyzes the trend and disease burden injury deaths Chinese population from 2004 2010, using data National Disease Surveillance Points (DSPs) system, as classified based on International Classification Disease-10th Revision (ICD-10). We observed that death accounted nearly 10% China throughout period 2004–2010, mortality rates were...
Background Cardiovascular disease (CVD) is the top cause of death in China. We aimed to identify trends cause-specific CVD mortality a rapidly developing country, thereby providing evidence for prophylaxis.
We introduce Baichuan-Omni-1.5, an omni-modal model that not only has understanding capabilities but also provides end-to-end audio generation capabilities. To achieve fluent and high-quality interaction across modalities without compromising the of any modality, we prioritized optimizing three key aspects. First, establish a comprehensive data cleaning synthesis pipeline for multimodal data, obtaining about 500B (text, audio, vision). Second, audio-tokenizer (Baichuan-Audio-Tokenizer) been...
High blood urea nitrogen (BUN) is associated with adverse outcomes in patients cardiac disease risks. However, no study has explored whether BUN can predict the risk of cardiovascular (CVD) healthy older population. This aims to explore incidence and factors CVD among a population community China.
Background There remain concerns regarding the technical feasibility of endoscopic resection for large gastrointestinal stromal tumors (GISTs), mainly relating to risk tumor rupture and adequacy margins. This study aimed evaluate therapeutic outcomes newly developed no-touch full-thickness (NT-EFTR) technique GISTs. Methods In this retrospective study, 92 patients with gastric GISTs undergoing NT-EFTR were included. Clinicopathological, endoscopic, follow-up data collected analyzed. Results...
Leonurine is a natural product unique to the Lamiaceae plant
Background: Irritable bowel syndrome (IBS) is a functional disorder characterized by abdominal pain and abnormalities in defecation associated with psychiatric disorders such as depression anxiety due to the dysfunction of brain-gut axis. This study aims determine whether trans-Resveratrol affects chronic-acute combined stress (CACS)-induced IBS-like symptoms including depression, intestinal dysfunction. Methods: ICR male mice were exposed CACS for 3 weeks. administrated daily (2.5, 5, 10...
This study investigates the constitution of traditional Chinese medicine (TCM) among women who want to be pregnant in one year and explores factors related TCM constitution.This was conducted on participated free preconception check-ups provided by Zhabei District Maternity Child Care Center Shanghai, China. The information regarding female demographic characteristics, physical condition, history pregnancy childbearing, diet behavior, social psychological collected, assessment performed....
Metabolic syndrome (MetS), a clustering of traditional cardiovascular risk factors (CVRF), is currently one the major global public health burdens. However, associations between MetS and non-traditional CVRF represented by uric acid (UA), homocysteine (HCY) hypersensitive C-reactive protein (HsCRP) have not been well explored in elderly population, especially when considering body mass index (BMI).Participants from Shanghai Elderly Cardiovascular Health (SHECH) study cohort 2017 were...
Hyperhomocysteinemia (HHcy) and abdominal obesity are risk factors for metabolic syndrome (MetS) death from cardiovascular disease (CVD). Recent studies have shown a correlation between HHcy obesity, suggesting that they may combined effect on the of MetS CVD mortality. However, this suspicion remains to be confirmed, particularly in elderly population. We explored their effects mortality among community population aged 65 above China.This prospective study enrolled 3,675 Chinese residents...
Abstract Background and Aims Anti-hypertensive agents are one of the most frequently used drugs worldwide. However, no blood pressure–lowering strategy is superior to placebo with respect survival in diabetic hypertensive patients. Previous findings show that Wnt co-receptors LDL receptor–related proteins 5 6 (LRP5/6) can directly bind several G protein–coupled receptors (GPCRs). Because angiotensin II type 1 receptor (AT1R) important GPCR regulating hypertension, this study examines...