A5059538459- SARS-CoV-2 and COVID-19 Research
- Animal Virus Infections Studies
- Respiratory viral infections research
- SARS-CoV-2 detection and testing
- COVID-19 Clinical Research Studies
- COVID-19 epidemiological studies
- COVID-19 and Mental Health
- Pneumonia and Respiratory Infections
- Viral gastroenteritis research and epidemiology
- Public Health and Environmental Issues
- Palliative and Oncologic Care
- Educational methodologies and cognitive development
- Oral microbiology and periodontitis research
- Health and Lifestyle Studies
- RNA and protein synthesis mechanisms
- Iron Metabolism and Disorders
- Consumer Attitudes and Food Labeling
- Nutritional Studies and Diet
- Bacterial Infections and Vaccines
- Immunotherapy and Immune Responses
- Diabetes and associated disorders
- Viral Infections and Immunology Research
- vaccines and immunoinformatics approaches
- Biosensors and Analytical Detection
- Antibiotic Resistance in Bacteria
Instituto de Investigación Nutricional
2021-2025
Hospital Nacional Cayetano Heredia
2023
Universidad Peruana Cayetano Heredia
2023
Abstract Background Peru implemented restrictive social distancing policies during the COVID-19 pandemic. Few studies have examined patterns of nasopharyngeal pneumococcal carriage and related antimicrobial resistant genes (ARGs), particularly in community-based settings with intense policies. Methods Nasopharyngeal swabs were systematically obtained weekly from children adults enrolled two household-based prospective pre-pandemic (2019-2020) pandemic (2020-2021) cohorts Lima, Peru. Selected...
The COVID-19 vaccine candidate CVnCoV comprises sequence-optimized mRNA encoding SARS-CoV-2 S-protein encapsulated in lipid nanoparticles. In this phase 2a study, we assessed reactogenicity and immunogenicity of two or three doses younger older adults.Younger (18-60 years) (>60 adults were enrolled sites Panama Peru to receive either 6 12 µg licensed control vaccines 28 days apart; subsets received a booster dose on Day 57 180. Solicited adverse events (AE) reported for 7 unsolicited AEs 4...
Abstract Background We assessed the prevalence and incidence of SARS‐CoV‐2 infections in a prospective study households Lima, Peru. Methods Households with child, young adult 18–50 years, an age >50 years peri‐urban Lima were followed twice‐a‐week household visits during 2‐month period. Nasal swabs saliva specimens collected twice weekly, nasopharyngeal weekly from each participant, regardless symptoms. Laboratory‐confirmed infection was defined by two RT‐PCR tests any within week. Blood...
Introducción : Los analizadores hematológicos Beckman-Coulter han utilizado el Factor de anémica microcítica (Maf®) como herramienta detección sencilla y económica para la temprana deficiencia hierro ( DH). Objetivo: determinar relación entre Maf® evaluar rendimiento diagnóstico en postulantes diferidos a donar sangre. Materiales Métodos: Estudio transversal. Se revisó 159 historias clínicas sangre por tener valores hemoglobina menores 12.5 gr/dl (mujeres) 13.5 (varones) que acudieron al...
<title>Abstract</title> Given the local and systemic adverse reactions associated with whole cell pertussis vaccines combined diphtheria tetanus toxoids (DTP), acellular same (DTaP) were developed in 1990s. In comparison to DTP, DTaP demonstrated reduced reactogenicity equivalent or improved immunogenicity efficacy. However, there has been a resurgence of disease, particularly DTaP-vaccinated children, suggesting that immunity wanes more quickly vaccination. To elucidate differences immune...
Background: Few studies have prospectively evaluated SARS-CoV-2 infections in households. We assessed the prevalence and incidence of a prospective study households Lima, Peru.Methods: conducted cohort peri-urban district Peru. Households with at least child, young adult (age 18 to 50 years) an older age >50 years, were followed twice-a-week household visits during two-month period for health surveillance. Nasal swabs saliva specimens collected twice weekly, nasopharyngeal weekly from each...
Background: The COVID-19 vaccine candidate CVnCoV comprises sequence-optimized mRNA encoding SARS-CoV-2 S-protein encapsulated in lipid nanoparticles. In this phase 2a study, we assessed reactogenicity and immunogenicity of two or three doses younger older adults.Methods: Younger (18–60 years) (> 60 adults were enrolled sites Panama Peru to receive either 6 12 µg licensed control vaccines 28 days apart; subsets received a booster dose on Day 57 180. Solicited adverse events (AE) reported for...
Objetivo: Determinar la correlación entre glucosa salival y marcadores de disfunción célula beta en pacientes con Diabetes Mellitus tipo 2 (DM2). Materiales métodos: Estudio transversal llevado a cabo el Centro Investigación Diabetes, Obesidad Nutrición (CIDON) Lima, Perú durante año 2021. Se categorizó buen control metabólico (HbA1c<7%) mal (HbA1c≥7%). midió basal, HbA1c péptido C sangre. La se método glucosa-oxidasa. Spearman fue usada para determinar asociación los beta. Resultados:...
The continuous evolution of the SARS-CoV-2 pandemic has led to a high demand for diagnostic testing and major shortages in materials, especially low- middle-income countries. As an alternative individual samples, pooling respiratory samples been suggested. Previous studies have assessed performance pooling, mainly using nasopharyngeal detection SARS-CoV-2, but few examined more practical nasal swabs or saliva samples.To evaluate sensitivity, specificity, potential cost reduction swab (NS)...
Abstract Background Antibiotic resistant infections commonly occur in healthcare settings, but the prevalence of antibiotic genes (ARGs) healthy individuals community is unknown. We provide an initial assessment nasopharyngeal carriage ARGs conferring resistance to macrolides and/or lincosamides, including erm, mph, ABC-F, and lnu genes. Methods Nasopharyngeal swabs were systematically obtained at enrollment weekly thereafter from children adults enrolled a household-based prospective cohort...
Objetivo: determinar la relación entre el Ret-He con diferentes categorías según concentración de hemoglobina en candidatos a donar sangre. Materiales y Métodos: Se realizó un estudio transversal partir revisión 227 historias clínicas sangre durante mes diciembre del 2021 Servicio Banco Sangre Hemoterapia Hospital Cayetano Heredia. categorizó 3 grupos los niveles hemoglobina: Grupo 1: ≥12,5 g/dl (mujeres) - ≥13,5 (varones). 2: 12 ≥ mujeres <12.5 13 varones<13.5 g/dl. 3: <12 <13...
Background: The continuous evolution of the SARS-CoV-2 pandemic has led to a high demand for diagnostic testing and major shortages in materials, especially low- middle-income countries. As an alternative individual samples, pooling respiratory samples been suggested. Previous studies have assessed performance pooling, mainly using nasopharyngeal detection SARS-CoV-2, but few examined more practical nasal swabs or saliva samples.Objective: To evaluate sensitivity, specificity, potential cost...
La aparición de la pandemia causada por el virus SARS-CoV-2 tomó desprevenido al mundo entero. Sin embargo, reacción ha sido asombrosa. En poco más un año del virus, se cuenta con cientos vacunas en desarrollo y varias ellas vienen siendo aplicadas casi todo mundo. este manuscrito revisamos estado actual las vacunas, resaltando aquéllas que cuentan estudios Fase III (eficacia) o IV (efectividad). Además, variantes interés preocupación detectadas hasta momento qué sabe sobre eficacia contra ellas.