A5006163227- SARS-CoV-2 and COVID-19 Research
- Animal Virus Infections Studies
- Genetic Associations and Epidemiology
- Vaccine Coverage and Hesitancy
- Adrenal and Paraganglionic Tumors
- Bioinformatics and Genomic Networks
- Estrogen and related hormone effects
- Gut microbiota and health
- COVID-19 and Mental Health
- Folate and B Vitamins Research
- Viral Infections and Immunology Research
- Kawasaki Disease and Coronary Complications
- Genetic Syndromes and Imprinting
- Cardiovascular Disease and Adiposity
- Radiopharmaceutical Chemistry and Applications
- Viral gastroenteritis research and epidemiology
- Male Breast Health Studies
- Mechanical Circulatory Support Devices
- Congenital Heart Disease Studies
- Fatty Acid Research and Health
- Immunotherapy and Immune Responses
- Lipid metabolism and disorders
- COVID-19 Clinical Research Studies
- Cancer, Hypoxia, and Metabolism
- Pharmacological Effects of Medicinal Plants
Instituto de Investigación Nutricional
2021-2024
Texas Oncology
2012-2017
The COVID-19 vaccine candidate CVnCoV comprises sequence-optimized mRNA encoding SARS-CoV-2 S-protein encapsulated in lipid nanoparticles. In this phase 2a study, we assessed reactogenicity and immunogenicity of two or three doses younger older adults.Younger (18-60 years) (>60 adults were enrolled sites Panama Peru to receive either 6 12 µg licensed control vaccines 28 days apart; subsets received a booster dose on Day 57 180. Solicited adverse events (AE) reported for 7 unsolicited AEs 4...
Introduction Our objective was to explore the effect of reduction saturated fat (SAF) intake on cardiovascular disease, mortality and other health-related outcomes in adults. Methods We conducted an umbrella review, searching Medline, Scopus, EMBASE, Cochrane Library, LILACS databases for systematic reviews from December 1, 2012, 2022. have included meta-analyses randomized controlled trials (RCTs) cohort studies. extracted sizes (95%CI), heterogeneity ( I 2 ), evidence quality rating based...
Alterations in subcortical brain structure volumes have been found to be associated with several neurodegenerative and psychiatric disorders. At the same time, genome-wide association studies (GWAS) identified numerous common variants structure. In this study, we integrate these findings, aiming identify proteins, metabolites, or microbes that a putative causal via two-sample Mendelian randomization approach. This method uses genetic as instrument variables potentially associations between...
Objective To determine the short-, mid-, and long-term complications after multisystem inflammatory syndrome in children (MIS-C) over a 24-month follow-up period hospital Lima, Peru, 2020–2022, to explore differences according immunomodulatory treatment received type of SARS-CoV-2 virus circulating. Methods Ambispective study <14 years age diagnosed with MIS-C at Hospital Nacional Edgardo Rebagliati Martins (HNERM). Results A total 62 were admitted MIS-C. The most common short-term...
This report presents a case of one-month three-day-old full-term female infant with hydrometrocolpos (HMC) and post-axial polydactyly whose first clinical sign was acute intestinal obstruction hydroureteronephrosis, caused by compression the structures due to increasing size cystic-like pelvic mass. is HMC complicated in Peru. It raises importance on prenatal diagnosis, management complications HMC. Although it rare, clinicians should have as an option when discussing abdominal cystic masses...
Objectives To characterize factors associated with parental willingness for their children participation in a COVID-19 vaccine trial, use of different vaccines and acceptance third dose. Methods Parents aged 12–17 years Lima, Perú were asked to complete an online questionnaire via social networks, from November 9, 2021, April 23, 2022. We calculated crude adjusted prevalence ratios 95% confidence intervals compare the mentioned outcomes. Results From 523 parents responding, 374 completed...
Background: The COVID-19 vaccine candidate CVnCoV comprises sequence-optimized mRNA encoding SARS-CoV-2 S-protein encapsulated in lipid nanoparticles. In this phase 2a study, we assessed reactogenicity and immunogenicity of two or three doses younger older adults.Methods: Younger (18–60 years) (> 60 adults were enrolled sites Panama Peru to receive either 6 12 µg licensed control vaccines 28 days apart; subsets received a booster dose on Day 57 180. Solicited adverse events (AE) reported for...
Alterations in subcortical brain structure volumes have been found to be associated with several neurodegenerative and psychiatric disorders. At the same time, genome-wide association studies (GWAS) identified numerous common variants structure. In this study, we integrate these findings, aiming identify proteins, metabolites, or microbes that a putative causal via two-sample Mendelian randomization approach. This method uses genetic as instrument variables potentially associations between...
Leptomeningeal metastases (LM) affect 5–8% of cancer patients; median survivals historically have ranged from 12–16 weeks. Earlier intervention, multimodal treatment, intrathecal chemotherapy, and targeting relevant molecular drivers may improve outcomes. Under an IRB-approved protocol, we retrospectively reviewed our experience with consecutively diagnosed LM patients seen at the Austin Brain Tumor Center. Relevant data was extracted medical records images. Ninety-two consecutive were...
La aparición de la pandemia causada por el virus SARS-CoV-2 tomó desprevenido al mundo entero. Sin embargo, reacción ha sido asombrosa. En poco más un año del virus, se cuenta con cientos vacunas en desarrollo y varias ellas vienen siendo aplicadas casi todo mundo. este manuscrito revisamos estado actual las vacunas, resaltando aquéllas que cuentan estudios Fase III (eficacia) o IV (efectividad). Además, variantes interés preocupación detectadas hasta momento qué sabe sobre eficacia contra ellas.