A5024400278- Neurogenesis and neuroplasticity mechanisms
- Neuroinflammation and Neurodegeneration Mechanisms
- Neuroscience of respiration and sleep
- High Altitude and Hypoxia
- Phosphodiesterase function and regulation
- Epigenetics and DNA Methylation
- Viral Infections and Immunology Research
- Cytokine Signaling Pathways and Interactions
- Pediatric health and respiratory diseases
- Pain Mechanisms and Treatments
- Acute Myeloid Leukemia Research
- Alkaloids: synthesis and pharmacology
- Diet and metabolism studies
- Stress Responses and Cortisol
- Autism Spectrum Disorder Research
- Genetics and Neurodevelopmental Disorders
- Mesenchymal stem cell research
- Respiratory viral infections research
- Biopolymer Synthesis and Applications
- Respiratory Support and Mechanisms
- Menopause: Health Impacts and Treatments
- HIV/AIDS drug development and treatment
- Neurological Disease Mechanisms and Treatments
- Circular RNAs in diseases
- Histone Deacetylase Inhibitors Research
Osmania University
2025
Bharathidasan University
2019-2023
Deccan School of Hospital Management
2021-2023
Jawaharlal Nehru Technological University, Hyderabad
2022
Jawaharlal Nehru Technological University, Kakinada
2022
Nilai University
2021
According to the World Health Organization (WHO), cancer is second-highest cause of mortality worldwide, killing nearly 9.6 million people annually. Despite advances in diagnosis and treatment during last couple decades, it remains a serious concern due limitations currently available management strategies. Therefore, alternative strategies are highly required overcome these glitches. In addition, many etiological factors such as environmental genetic initiate activation Janus kinase...
Background: This study explores the formulation and effectiveness of a Rhodiola rosea phytosomal gel for enhancing wound healing. Object: The ethanolic extract roots, rich in bioactive compounds like alkaloids flavonoids, was optimized into complex to improve absorption dermal retention. Method: Characterization through GC-MS revealed compounds, such as 2-Heptadecenal Bicyclo[ 4.1.0]Heptane 7-Pentyl. FTIR confirmed successful encapsulation within phospholipid bilayer, while SEM showed...
Aspirin has been reported to prevent memory decline in the elderly population. Adult neurogenesis hippocampus recognized as an underlying basis of learning and memory. This study investigated effect aspirin on spatial correlation with regulation hippocampal microglia brains ageing experimental mice. Results from novel object recognition (NOR) test, Morris water maze (MWM), cued radial arm (cued RAM) revealed that treatment enhances working Further, co-immunohistochemical assessments brain...
Neural stem cell (NSC) mediated adult neurogenesis represents the regenerative plasticity of brain. The functionality neurogenic process appears to be operated by neuroblasts, multipotent immature neuronal population While neuroblasts have been realized play a major role in synaptic remodeling and immunogenicity, neurodegenerative disorders characterized failure terminal differentiation, maturation, integration survival newborn neuroblasts. Advancement understanding impaired...
Abstract Aspirin treatment is the most widely used preventive measure against cardiovascular diseases. also expected to provide beneficial effects on brain. However, association between aspirin and neurocognitive functions a subject of debate. Ample reports strongly advocate that mild dose positively modulates hippocampal plasticity responsible for memory. selective cyclooxygenase (COX)-2 inhibitor but underlying mechanism through which neuroplasticity remains unclear. Adult neurogenesis in...
Abstract Aim After focal cerebral ischemia, intermittent hypoxia therapy (IHT) could be used as a non-invasive method to stabilize and stimulate neurogenesis in the innate stem cell niche brain, disrupt glial scar around infarct increase neuroblast migration striatal area. Methods We induced ischemia Wistar albino rats using MCAo model. A week later, animals were subjected (12%O 2 , 4hr/day) for period of 14 days. Post-treatment analysis functional recovery cellular regeneration was done...
Cognitive disorders, including dementia and Alzheimer's disease, pose substantial global health challenges, demanding effective prevention treatment strategies. Intermittent Hypoxia Therapy (IHT), involving brief exposures to reduced oxygen levels, is a novel approach with potential cognitive benefits. This study investigates the effects of (IHT) on behavior in Wistar albino rats through comprehensive behavioral experiments, Open Field Test (OFT) Morris Water Maze (MWM). The results reveal...
Abstract Purpose In-vivo Hypoxia chamber is sought after for research on sleep apnea, among others. Recently hypoxia chambers are utilized to create intermittent hypoxia, thereby utilizing it as a treatment strategy. The commonly used Invivo hypoxic only monitor oxygen levels and fail read up vital factors like CO2 buildup, humidity In addition, these devices expensive make them unaffordable many labs. Methods Here we report lab-designed assembled Arduino microcontroller-based with automatic...
1) Abstract Objectives Promoting neurogenesis mediated recovery is one of the most sought after strategies in cerebral stroke. In this paper we elucidate how related genes are altered early stroke environment, to hint at potential pathways for therapeutic recovery. Materials and Methods Around 97 microarray datasets derived from affected rat brains were collected NCBI-GEO. Datasets normalized subjected meta-analysis Network Analyst identify differentially expressed genes. Gene enrichment...