A5083407320- Infant Nutrition and Health
- Reproductive Physiology in Livestock
- Biosensors and Analytical Detection
- Cancer-related molecular mechanisms research
- Signaling Pathways in Disease
- Bacteriophages and microbial interactions
- Genetic and phenotypic traits in livestock
- Peroxisome Proliferator-Activated Receptors
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Cardiac Fibrosis and Remodeling
- Immune Cell Function and Interaction
- SARS-CoV-2 and COVID-19 Research
- HIV/AIDS drug development and treatment
- Medicinal Plants and Neuroprotection
- Genomics and Phylogenetic Studies
- Pharmacological Effects of Natural Compounds
- Poxvirus research and outbreaks
- HIV Research and Treatment
- Electrochemical sensors and biosensors
- Nutrition, Genetics, and Disease
- Plant Disease Resistance and Genetics
- Metabolism, Diabetes, and Cancer
- Animal Genetics and Reproduction
- RNA and protein synthesis mechanisms
- Natural Antidiabetic Agents Studies
University of Campania "Luigi Vanvitelli"
2024-2025
Virtual University of Pakistan
2020-2023
National University of Sciences and Technology
2020-2022
COMSATS University Islamabad
2018
p27Kip1 is a key cell cycle gatekeeper governing the timing of Cyclin-dependent kinase (CDK) activation/inactivation and, consequently, proliferation. Structurally, protein largely unfolded, feature that strongly increases its plasticity and interactors enhances number regulated cellular processes. p27Kip1, like other intrinsically unstructured proteins, post-translationally modified on several residues. These modifications affect localization address for specific interactions/functions....
Type 2 diabetes mellitus (T2DM) is a complex metabolic disorder that characterized by hyperglycemia, insulin resistance, and lack of production. It has been previously reported Thymus serpyllum therapeutic potential against many diseases. To investigate the antidiabetic action serpyllum, this study aimed to analyze its restorative impact in diabetic mice, which it was administered diet. Diabetes induced BALB/c mice fed with high-fat diet two intraperitoneal injections streptozotocin. With...
AbstractAbstractDairy cows undergo immense stress and experience autoimmune reactions during the transition period, majorly due to generation of ROS in body. So, pharmacological approaches are needed manage oxidative cows. Recently, use phytochemicals as feed additives cows' nutrition has gained interest managing various disease conditions. In current study, we have evaluated potential effects derived from methanolic extract Thymus serpyllum against autoimmunity via inhibition bovine nuclear...
In current COVID-19 pandemic, when there is no specific antiviral treatment and vaccine available yet, many nutritional supplements have caught the attention to manage disease. Lactoferrin one of a natural supplement found in milk livestock mammals has immunomodulation property due its iron withholding ability capacity bind multiple cellular receptors. The lactoferrin been evaluated against viruses including SARS-CoV which closely related SARS-CoV-2 (causative agent COVID-19). Furthermore,...
Lactoferrin, a pleiotropic and multivalent natural protein, derived from bovine camel milk has become the center of attention in current scientific arena due to its divers immune-modulation inflammation related properties. Lactoferrin immense role host immune defenses as several important cells have surface receptors specific for lactoferrin. It been studied at great depth contribution system covered this chapter interface between innate adaptive defenses. The medicinal biological benefits...
Transition nuclear proteins (TNPs), the principal identified in condensing spermatids chromatin, have been found to play a key role histone displacement and chromatin condensation during mammalian spermatogenesis. One such gene belonging TNP family called TNP1 is abundantly expressed regulation of spermatogenesis, its sequence remarkably well conserved among mammals. Genomic analysis, by sequencing computational approach, was used identify novel polymorphisms evaluate molecular expression...
CCR5 is an important CC chemokine receptor for the normal entry of Human Immunodeficiency Virus (HIV) in host cells. Mutations this gene have been linked with delayed HIV infection, therefore, current case-control study was conducted to identify genetic polymorphism Pakistani population and evaluate its association resistance infections. All regulations MOOSE Helsinki Declaration were strictly followed during entire study. DNA extracted from blood samples positive negative patients....
Cardiac hypertrophy is the major pathway by which neurohormonal and mechanical stimuli act upon cardiomyocytes gives response to these stimuli. It leads heart failure ventricular dilation main root of mortality in western world. Many molecular targets are controlling cardiac development may influence growth factors signaling, cytokine release gene expression. Through clinical trials on different models, recent research shows that might be inhibited or reversed. These findings have developed...