A5062830143- Salivary Gland Disorders and Functions
- Systemic Lupus Erythematosus Research
- Salivary Gland Tumors Diagnosis and Treatment
- Systemic Sclerosis and Related Diseases
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Rheumatoid Arthritis Research and Therapies
- Autoimmune and Inflammatory Disorders Research
- Monoclonal and Polyclonal Antibodies Research
- IgG4-Related and Inflammatory Diseases
- Nutrition and Health Studies
- Spondyloarthritis Studies and Treatments
- Diabetes and associated disorders
- Health, Work, and Social Studies in Poland
- Urticaria and Related Conditions
- Ocular Surface and Contact Lens
- Inflammasome and immune disorders
- Inflammatory Myopathies and Dermatomyositis
- Renal Diseases and Glomerulopathies
- Oral Health Pathology and Treatment
- Bone and Joint Diseases
- Public health and occupational medicine
- Lymphoma Diagnosis and Treatment
- Dermatologic Treatments and Research
- Neuroendocrine Tumor Research Advances
- Immunodeficiency and Autoimmune Disorders
National Institute of Geriatrics, Rheumatology and Rehabilitation
2015-2024
Arthritis and Rheumatism Associates
2024
ERN GUARD-Heart
2023
Postgraduate School of Molecular Medicine
2023
Bogomolets National Medical University
2020
Sapienza University of Rome
2013
The main two aims collagene therapy in rheumatology are supporting pain treatment inflammatory diseases and element of multimodality non-inflammatory diseases. <br/>In rheumatic can coexist the different type such as nociceptive pain, neuropathic nociplastic well pain. This last ententity resulting from activity process, special environment i.e. pro-inflammatory cytokines, especially interleukin-6 (IL-6), tumor necrosis factor (TNF), IL-1 or chemokines, be seen a possible combination...
The objective of this study was to determine the length delay in diagnosis inflammatory rheumatic diseases, and indicate main factors responsible for such delays.A retrospective multi-centre questionnaire survey carried out among 197 patients with diagnosed diseases or undergoing diagnostic process.The most common early symptoms disease included joint pain (94%), swelling (78%), morning stiffness (77%), fatigue (76%), sleep disturbed by (74%). When asked about reasons seeking medical help,...
Abstract The assessment of skin fibrosis is vital for the diagnosis and monitoring treatment in systemic sclerosis (SSc)—a severe autoimmune disease. elastography a technique through evaluation strain. We compared efficacy shear wave (SWE) commonly used modified Rodnan score (RSS) SSc. study included 40 SSc patients 28 healthy individuals, with exclusion individuals other skin/autoimmune diseases. Skin thickness using RSS strain SWE were assessed same 20 body localizations . Subjects’...
The aim of this study was to assess the correlation between symptoms depression and course clinical picture rheumatoid arthritis (RA).120 patients with RA were included in study: 104 (87%) female 16 (13%) male patients. All studied completed following questionnaires: Beck Depression Inventory (BDI), Ford Insomnia Response Stress Test (FIRST), Athens Scale (AIS) Health Assessment Questionnaire (HAQ). serum levels IL-1β, TNF-α, IL-6 measured using standard ELISA assays at time first...
The objective of the study was to assess prevalence symptoms depression and insomnia among patients with rheumatoid arthritis osteoarthritis in comparison individuals without chronic diseases. carried out at National Institute Geriatrics, Rheumatology Rehabilitation, included 229 persons. participants were divided into following groups: group I - 120 arthritis, II 58 osteoarthritis, III 51 healthy no confirmed (control group). Symptoms by a multiple-choice self-reported Beck Depression...
Enhanced/disturbed activities of monocytes are crucial for perpetuation and development rheumatoid arthritis (RA). Therefore, knowledge about monocyte regulation molecular pathways operating within early in the course RA may help to predict progression full-blown disease. We aimed investigate profile miRNAs expression circulating monocyte-related cytokines sera individuals at undifferentiated (UA) stage, wich could serve as new biomarkers development.Magnetically sorted from peripheral blood...
Background Antiphospholipid syndrome (APS) is a multisystemic autoimmune disorder characterized by thrombotic events and/or gestational morbidity in patients with antiphospholipid antibodies (aPL). In previous single center study, APS-related clinical manifestations that were not included the classification criteria (livedo reticularis, thrombocytopenia, leukopenia) associated presence of circulating immune-complexes (CIC) formed beta-2-glycoprotein-I (B2GP1) and anti-B2GP1 (B2-CIC). We have...
The rheumatoid factor (RF) is present in numerous autoimmune disorders, although its role many of them remains a subject research. study assesses the RF as an immunological and prognostic primary Sjögren's syndrome (pSS). Seventy-five pSS patients (mean age 50.03 ± 15.1), 65 (87%) females, 10 (13%) males. WBC, CRP, RF, ESR, gammaglobulins, C4, C3 component complement, cryoglobulins, ANA, anti-SS-A, anti-SS-B antibodies were determined. disease activity assessed with ESSDAI. Minor salivary...
Primary Sjögren syndrome (pSS) is a systemic autoimmune disease that mainly affects the salivary and lacrimal glands, leading to their progressive destruction.The primary aim of this study was verify whether shear wave elastography (SWE) glands can be used differentiate patients with pSS from healthy controls. The secondary assess there are any associations between SWE values, results other ocular tests included in diagnosis (the Schirmer test, staining score [OSS]), subjective symptoms eye...