- Flame retardant materials and properties
- Synthesis and biological activity
- Synthesis and properties of polymers
- Synthesis of Organic Compounds
- Molecular Sensors and Ion Detection
- Synthesis and Characterization of Heterocyclic Compounds
- Conducting polymers and applications
- Semiconductor materials and interfaces
- Synthesis and characterization of novel inorganic/organometallic compounds
- Electrochemical sensors and biosensors
- Organic Light-Emitting Diodes Research
- Nonlinear Optical Materials Research
- Organic Electronics and Photovoltaics
- Thermal and Kinetic Analysis
- Analytical Chemistry and Sensors
- Organophosphorus compounds synthesis
- Electrochemical Analysis and Applications
- Synthesis of Tetrazole Derivatives
- Chemical Reaction Mechanisms
- Polydiacetylene-based materials and applications
- Porphyrin and Phthalocyanine Chemistry
- Polymer Nanocomposites and Properties
- Multicomponent Synthesis of Heterocycles
- TiO2 Photocatalysis and Solar Cells
- Inorganic and Organometallic Chemistry
Fırat University
2016-2025
Division of Chemistry
2020
Advanced functional polymeric materials can possess chemical reactivity, catalytic properties, photosensitivity, electrical conductivity, biological activity, biocompatibility, pharmacological selective separation, and energy conversion of traditional polymers. Because these the production characterization polymers has become an essential part modern industry advanced technology. Methacrylate are highly versatile owing to their exceptional properties including superior optical transparency,...
ABSTRACT Cancer treatment requires novel compounds with potent cytotoxic and genotoxic properties to effectively target cancer cells. In this study, new hybrid cyclotriphosphazene were synthesized, characterized, evaluated for their biological activity. Cytotoxicity against A2780 Caco‐2 cell lines was assessed via the MTT assay, while effects at 60–70% viability examined using Comet assay. Apoptotic cells identified through TUNEL analyses, reactive oxygen species levels measured. Results...
Phosphazenes have drawn a great deal of interest over the past 20 years as potentially useful building block for fabrication fluorescent materials. The main objective this work is to explore novel derivatives produced by coumarins, class chemicals well-known their photophysical importance, and cyclophosphazenes. UV absorbance, fluorescence emission, quantum yield, lifetime measurements were conducted comprehend optical properties. Furthermore, single-crystal X-ray analysis theoretical...
GRAPHICAL ABSTRACT Synthesis, structural and thermal characterizations in vitro cytotoxic activities of new cyclotriphosphazene derivativesAll authorsKenan Koran, Çiğdem Tekin, Eray Çalışkan, Suat Süleyman Sandal http://orcid.org/0000-0002-8916-3329 & Ahmet Orhan Görgülühttps://doi.org/10.1080/10426507.2017.1315420Published online:05 July 2017
The present study was designed to both synthesize phenylacrylonitrile compounds (1a–k) and their anti-tumor activities on human breast cancer cell line (MCF-7) were determined. structures of all the defined by melting point, elemental analysis, FT-IR, 1H, 13C, 13C-APT, HETCOR-NMR spectroscopy. Anti-tumor these viability evaluated using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay against MCF-7. MCF-7 lines treated with 1, 5, 25, 50, 100 μM concentrations for 24 h. At...
Considering vital roles of trace copper ions for the health humans, it is critical to sensitively detect in foodstuffs. Herein, an ultrasensitive and cost–effective coumarin based fluorescent strategy with a "turn–off" signal was developed specific detection Cu2+ ions. Synthesis 6,7-dihydroxy-3-(3-methylphenyl)coumarin (TMAC) probe performed characterized. The presented excellent selectivity. limit sensor can reach as low 5.13 nM ACN/H2O (v/v=95/5) buffered by 5 μM HEPES buffer at pH = 7.0,...
The hexachlorocyclotriphosphaze compound (N3P3Cl6, HCCP) was reacted with excess (E)-(1-(4'-oxyphenyl)-3-(substituted-phenyl)prop-2-en-1-ones (2-11) to produce hexakis[(1-(4-oxyphenyl)-3-(substituted-phenyl)prop-2-en-1-one)]cyclotriphosphazenes (CP 2-11). structures of products 2-11) were confirmed using elemental analysis, FT-IR, MS spectral analysis as well 31P, 1H and 13C-APT NMR techniques their thermal properties determined by TGA DSC techniques. HOMO-LUMO energy gap chemical reactivity...