A5044281603- Synthesis and biological activity
- Synthesis and properties of polymers
- Synthesis of Organic Compounds
- Synthesis and Characterization of Heterocyclic Compounds
- Flame retardant materials and properties
- Chemical Synthesis and Analysis
- Conducting polymers and applications
- Click Chemistry and Applications
- Organic Electronics and Photovoltaics
- Carbohydrate Chemistry and Synthesis
- Organic Light-Emitting Diodes Research
- Thermal and Kinetic Analysis
- TiO2 Photocatalysis and Solar Cells
- Synthesis and characterization of novel inorganic/organometallic compounds
- Silicone and Siloxane Chemistry
- Luminescence and Fluorescent Materials
- Semiconductor materials and interfaces
- Electrochemical sensors and biosensors
- Polymer Nanocomposites and Properties
- Biochemical and Structural Characterization
- Polydiacetylene-based materials and applications
- Plant tissue culture and regeneration
- Epoxy Resin Curing Processes
- Energetic Materials and Combustion
- Quinazolinone synthesis and applications
Bingöl University
2017-2025
University of Florida
2013-2014
Phosphazenes have drawn a great deal of interest over the past 20 years as potentially useful building block for fabrication fluorescent materials. The main objective this work is to explore novel derivatives produced by coumarins, class chemicals well-known their photophysical importance, and cyclophosphazenes. UV absorbance, fluorescence emission, quantum yield, lifetime measurements were conducted comprehend optical properties. Furthermore, single-crystal X-ray analysis theoretical...
Advanced functional polymeric materials can possess chemical reactivity, catalytic properties, photosensitivity, electrical conductivity, biological activity, biocompatibility, pharmacological selective separation, and energy conversion of traditional polymers. Because these the production characterization polymers has become an essential part modern industry advanced technology. Methacrylate are highly versatile owing to their exceptional properties including superior optical transparency,...
ABSTRACT Cancer treatment requires novel compounds with potent cytotoxic and genotoxic properties to effectively target cancer cells. In this study, new hybrid cyclotriphosphazene were synthesized, characterized, evaluated for their biological activity. Cytotoxicity against A2780 Caco‐2 cell lines was assessed via the MTT assay, while effects at 60–70% viability examined using Comet assay. Apoptotic cells identified through TUNEL analyses, reactive oxygen species levels measured. Results...
GRAPHICAL ABSTRACT Synthesis, structural and thermal characterizations in vitro cytotoxic activities of new cyclotriphosphazene derivativesAll authorsKenan Koran, Çiğdem Tekin, Eray Çalışkan, Suat Süleyman Sandal http://orcid.org/0000-0002-8916-3329 & Ahmet Orhan Görgülühttps://doi.org/10.1080/10426507.2017.1315420Published online:05 July 2017
The hexachlorocyclotriphosphaze compound (N3P3Cl6, HCCP) was reacted with excess (E)-(1-(4'-oxyphenyl)-3-(substituted-phenyl)prop-2-en-1-ones (2-11) to produce hexakis[(1-(4-oxyphenyl)-3-(substituted-phenyl)prop-2-en-1-one)]cyclotriphosphazenes (CP 2-11). structures of products 2-11) were confirmed using elemental analysis, FT-IR, MS spectral analysis as well 31P, 1H and 13C-APT NMR techniques their thermal properties determined by TGA DSC techniques. HOMO-LUMO energy gap chemical reactivity...
The first total synthesis of Rolloamide B, a cyclic proline-enriched heptapeptide, is reported. This work features solution phase benzotriazole-mediated peptide ligating native amino acids.
Peptides are one of the leading groups compounds that have been subject a great deal biological research and still continue to attract researchers' attention. In this study, series tripeptides based on tyrosine amino acids were synthesized by triazine method. The cytotoxicity properties all against human cancer cell lines (MCF-7), ovarian (A2780), prostate (PC-3), colon (Caco-2) determined 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide assay method, % viability logIC50 values...
Abstract Both synthetic chemistry and polymer science, benefiting from click chemistry, have paved the way for easy synthesis use of compounds in various application areas. In this work, a chemoselective polymerization reaction (for 1 ) which occurred further step 2 was carried out through monomer obtained tyrosine with propargyl amine (PA) methyl methacrylate. Polymer synthesized azido end chalcone carrying alkyne its side chain by using chemistry. The average activation energy polymers...
Abstract The cyclotriphosphazenes, which constitute an important class of inorganic compounds, can show new properties in the medical or technological fields depending on substituted organic/inorganic groups. Herein, we aimed to determine electrical and theoretical nanographene‐doped chalcone derivatives dioxybiphenyl‐bridged dispiro‐cyclotriphosphazenes. For this aim, a series spiro‐cyclotriphosphazenes ( 3 – g ) have been synthesized by reaction dispiro‐cyclotriphosphazene with 1 ),...
Unprotected O-acylated serine and threonine isopeptides have been synthesized, their conversion to native tripeptides tetrapeptides by O-to N-terminus transfer investigated.Ligations involving 8-and 11-membered cyclic transition states are shown experimentally computationally be more favorable than intermolecular cross-ligations.
Amino acid conjugates are described by the reaction of amino acids with bioactive organic groups such as vitamins, hormones, flavonoids, steroids, and sugars. In this study, 12 new were synthesized cinnamic derivatives various acids. Cytotoxic studies against four different human cancer cells (MCF7, PC-3, Caco-2, A2780) carried out MTT assay method at five concentrations. The structure-activity relationships based on cell viability rates evaluated. To compare anticancer activities compounds...
Bu çalışma, kalkon ve kumarin grupları içeren amino asit konjugatlarının dielektrik özellikleri termal kararlılıklarının karşılaştırmalı bir analizini içermektedir. konjugatların elektriksel davranışını incelemek amacıyla sabiti, kaybı AC iletkenliği araştırılırken, kararlılıklarını için termogravimetrik analiz (TGA) kullanılmıştır. Konjugatlar, veya yapılarının omurgalarına klik kimyası ile dahil edilmesiyle sentezlenmiştir. Dielektrik sabiti ölçümleri, bazlı konjugatlarının, sisteminin...
Abstract The biological activity of both cyclophosphazenes and peptides makes these compounds important for new studies in medicinal chemistry. For this purpose, five different phosphazene‐peptide conjugates synthesized from dichlorocyclotriphosphazene tyrosine‐containing tripeptides. were evaluated their vitro cytotoxic activities against human breast (MCF‐7) colon (Caco‐2) cancer cell lines using MTT assay. derivatives induced death through DNA damage, with notable effects Caco‐2 lines....