Lei Liu

ORCID: 0000-0002-2227-8789
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About
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Research Areas
  • Aquaculture disease management and microbiota
  • Invertebrate Immune Response Mechanisms
  • Mosquito-borne diseases and control
  • Insect symbiosis and bacterial influences
  • interferon and immune responses
  • Plant Virus Research Studies
  • Animal Virus Infections Studies
  • Environmental Toxicology and Ecotoxicology
  • Viral Infectious Diseases and Gene Expression in Insects
  • Insect and Pesticide Research
  • Toxoplasma gondii Research Studies
  • Pesticide and Herbicide Environmental Studies
  • Immune Response and Inflammation
  • Aquaculture Nutrition and Growth
  • Phytochemical compounds biological activities
  • Herpesvirus Infections and Treatments
  • Complement system in diseases
  • Immune Cell Function and Interaction
  • Insect Pest Control Strategies
  • RNA Interference and Gene Delivery
  • Nuclear Structure and Function
  • Retinoids in leukemia and cellular processes
  • Viral Infections and Vectors
  • Traditional and Medicinal Uses of Annonaceae
  • Research on Leishmaniasis Studies

Ningbo University
2018-2024

National Center for AIDS/STD Control and Prevention,China CDC
2019

Chinese Center For Disease Control and Prevention
2019

State Key Laboratory of Infectious Disease Prevention and Control
2019

Northwest A&F University
2007-2019

Institute of Refrigeration
2007

Abstract Aquaculture is an important source of high‐quality protein and plays a crucial role in ensuring global food security. However, viral diseases have caused significant damage to aquaculture production, making it necessary develop effective measures treat them. Although drugs are commonly used diseases, recent studies shown that crude extracts medicinal plants their active ingredients potential applications the treatment aquatic diseases. Furthermore, natural small molecule compounds...

10.1111/raq.12825 article EN Reviews in Aquaculture 2023-04-20

Abstract This study was conducted to investigate the effect of in ovo feeding (IOF) folic acid on folate metabolism, immune function and involved epigenetic modification broilers. A total 400 (Cobb) hatching eggs were randomly divided into four groups (0, 50, 100 150 µg injection at embryonic age 11 d), chicks hatched from each treatment six replicates with 12 broilers/replicate after incubation. The results indicated that, , 100- 150-µg injections improved hatchability. average daily gain...

10.1017/s0007114515004511 article EN British Journal Of Nutrition 2015-11-20

Spring viremia of carp virus (SVCV) causes devastating losses in aquaculture. Coumarin has an advantageous structure for the design novel antiviral agents with high affinity and specificity. In this study, we evaluated a hydroxycoumarin medicine, i.e., 7-(6-benzimidazole) coumarin (C10), regarding its anti-SVCV effects <i>in vitro</i> vivo</i>. Results showed that up to 12.5 mg/L C10 significantly inhibited SVCV replication epithelioma papulosum cyprini (EPC) cell line, maximum inhibitory...

10.24272/j.issn.2095-8137.2020.037 article EN 动物学研究 2020-01-01

Chronic pollution in aquatic ecosystems can lead to many adverse effects, including a greater susceptibility pathogens among resident biota. Trifloxystrobin (TFS) is strobilurin fungicide widely used Asia control soybean rust. However, it has the potential enter ecosystems, where may impair fish resistance viral infections. To explore environmental risks of TFS, we characterized antiviral capacities chronically exposed TFS and subsequently infected with spring viraemia carp virus (SVCV)....

10.24272/j.issn.2095-8137.2021.056 article EN 动物学研究 2021-01-01

Spring viremia of carp virus (SVCV) is globally widespread and poses a serious threat to aquatic ecology aquaculture due its broad host range. To develop effective agents control SVCV infection, we selected 16 naturally active small molecules assess their anti-SVCV activity. Notably, dihydroartemisinin (DHA) (100 µmol/L) (S, S)-(+)-tetrandrine (TET) (16 exhibited high antiviral effects in epithelioma papulosum cyprinid (EPC) cells, with inhibitory rates 70.11% 73.54%, respectively. The...

10.24272/j.issn.2095-8137.2022.234 article EN 动物学研究 2022-01-01

As the concentration of microplastics/microspheres (MPs) in coastal and estuarine regions increases, likelihood disease outbreaks epidemics also rises. Our study investigated impact polyvinyl chloride MPs (PVC-MPs) on white spot syndrome virus (WSSV) infection shrimp. The results revealed that PVC-MPs obviously increased WSSV replication vivo, leading to a high mortality rate among larvae facilitating horizontal transmission WSSV. Furthermore, data loads detected together with qPCR, agarose...

10.1021/acs.est.3c01566 article EN Environmental Science & Technology 2023-07-27
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