A5053619282- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Human Health and Disease
- Pediatric health and respiratory diseases
- Food Allergy and Anaphylaxis Research
- Dermatology and Skin Diseases
- Respiratory and Cough-Related Research
- Immunodeficiency and Autoimmune Disorders
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Zoonotic diseases and public health
- Ottoman and Turkish Studies
- Legal, Health, Environmental and COVID-19 Challenges
- Lymphatic Disorders and Treatments
- Myasthenia Gravis and Thymoma
- Healthcare Systems and Public Health
- Cardiovascular Issues in Pregnancy
- Kawasaki Disease and Coronary Complications
- Eosinophilic Esophagitis
- Parasites and Host Interactions
- Pneumocystis jirovecii pneumonia detection and treatment
- Digestive system and related health
- Respiratory viral infections research
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Child Nutrition and Water Access
- Inhalation and Respiratory Drug Delivery
Siberian State Medical University
2013-2024
Ministry of Health of the Russian Federation
2017-2023
Altai State Medical University
2022
Regional Children's Hospital No1
2020
Primary immunodeficiencies (PID) are a group of rare genetic disorders with multitude clinical symptoms. Characterization epidemiological and data via national registries has proven to be valuable tool studying these diseases. Materials Methods. The Russian PID registry was set up in 2017, by the National Association Experts (NAEPID). It is secure, internet-based database that includes detailed clinical, laboratory therapeutic on patients all ages. Results. contained information 2728 (60%...
Bronchial asthma (BA) and allergic diseases such as rhinitis (AR) atopic dermatitis (AtD) are the most common chronic diseases, prevalence of which is growing among child population with urbanization industrialization society. These place a heavy burden on patients, their families society whole, associated course, frequent exacerbations need for long-term therapy these diseases. Traditionally, data BA children based results program «International Study Asthma Allergies in Childhood», focused...
Hen’s egg allergy is one of the most common problems in pediatrics. This pathology associated with severe clinical manifestations, often a risk anaphylactic reactions. review presents current data on epidemiology and presentation, as well aspects natural history management hen’s allergy. The paper will provide allergenic proteins egg, including structure, physicochemical properties, IgE-binding capacity, cross-reactivity. Finally, practical information about immunization be presented.
Information on the prevalence of allergic and non-allergic bronchial asthma among children preschool age is limited due to insufficient amount studies. At same time, determining phenotype disease key choosing optimal therapy prognosis. The objective: establish in 3–6 years living urban areas Altai Territory, study sensitization spectrum. authors conducted a momentary population-based study, consisting two stages. screening stage, included 3205 attending educational institutions. Symptoms...
Plastic bronchitis (PB) is a rare disease that causes airway obstruction with large «rubber» bronchial casts in adults and children, mainly due to concomitant cardiac or pulmonary pathology. It involves the organization of exudate transudate, which takes form respiratory tract. Mortality PB reaches 50%. Exact epidemiological data are not known. In most patients, occurs context major diseases, can be conditionally divided into two groups: heart vascular secondary complication diseases....
The objective of the present work was to estimate prevalence and risk factors development allergic rhinitis among children at age from 3 6 years. cross-sectional study carried out in five cities Altai region during period 2015 2016. evaluated with use Russian language version ISAAC questionnaire filled up by parents children. A child whose answered affirmative question 'Did your have runny nose, nasal congestion, and/or sneezing absence cold symptoms acute viral infection last 12 months?'...
Background. Antiphospholipid syndrome develops at autoimmune diseases, pregnancy, or genetic predisposition, and it is characterized by high risk of thrombosis in arterial, venous, capillary vessels. This children rare, necrotic skin lesions occur the most extreme cases. Clinical case description . A child, 1 year old, with chicken pox has developed hemorrhagic rash on his back, swelling left shoulder forearm 4th day disease. Medical treatment included acyclovir, ceftriaxone, sodium heparin....
Aim. To perform a comparative analysis of leukopoiesis parameters and platelet count in peripheral blood with evaluation their changes the first 48 hours from urosepsis (US) verification hospitalized patients depending on outcome disease. Materials methods. A retrospective study included 40 US divided into group deceased ( n = 10) recovered 30) individuals. Along full clinical paraclinical examination, which is routine practice urology clinic case suspected (confirmed) sepsis, we performed...
According to numerous surveys food allergy affects up 2–6% of population in different countries and varies due factors including the prevalence helminths infestation. The data Russia are based on official medical statistics. study was performed as part «The Prevalence, Cost Basis Food Allergy Across Europe» (EU funded project № FP6-2006-TTC-TU-5 Proposal 045879 EuroPrevall). aim is create concept children opisthorchiasis endemic area epidemiological prevalence, risk clinical features. main...
Cryopyrin associated periodic syndromes (CAPS) are rare monogenic autoinflammatory diseases from the group of hereditary caused by a regulation defect inflammatory cytokines, in particular interleukin 1 β . They include familial cold syndrome (FCAS), Muckle–Wells (MWS), and neonatal-onset multisystem disease (CINCA/NOMID). Previously, was considered as triad symptoms — urticaria, deafness, reactive amyloidosis. Today, spectrum is constantly expanding: it includes fever, fatigue,...
The objectives of this study were to estimate prevalence asthma-like symptoms and allergic rhinitis in preschool children determine risk factors these diseases. Methods. This cross-sectional was conducted 5 cities Altai krai 2015 – 2016 included aged 3 6 years. Prevalence diseases assessed using the Russian version ISAAC questionnaire. Results. 11.1%, 18.0%. diagnoses asthma physician-confirmed 0.9% 6.4% 3205 children, respectively. Family history related increased ( О R 2.11; 95% CI 1.66...
Background. It is necessary to study the prevalence and risk factors of allergic rhinitis (AR) among pre-school children in order develop a disease prevention strategy. Objective. Our aim was prevalence, clinical allergological features, for AR living urban settings Altai Region. Methods. At screening stage, enrolled aged 3–6 years attending educational institutions 5 cities symptoms were determined using ISAAC questionnaire. The diagnosed if ≥ 2 (rhinorrhea, nasal breathing difficulty,...
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Background. To reveal the regularities of sensitization formation in children with atopic dermatitis (AD) first four years life. Methods. Continuous crosssectional study 69 an established diagnosis AD from age 0 to 4 was conducted. Severity assessed according SCORAD scale. Clinical examination included: general and biochemical blood tests, determination total IgE allergenspecific (IgEs) serum against most common epidermal food allergens ImmunoCAP, Phadia IDM (Sweden) technology. Results....
Aim of research: to evaluate the prevalence atopic dermatitis at 3–6-year-old children by applying russified version ISAAC questionnaire (International Study Asthma and Allergies in Childhood) determine risk factors.Materials Methods. Cross-section research was carried out five places Altai Territory (2015–2016). The AD determined with help Manual filled parents 3–5-year-old children. definition for current (cAD) used studies. Patient considered suffering from cAD if respondents’ pointed...
The severity of the disease is main factor for further treatment. Bronchoobstructive syndrome children widespread. Early detection and correct treatment eliminate clinical manifestation improve quality patients life. Criteria severity, as a rule, serve certain set paraclinical parameters used different nosological forms. In particular, decrease in function external respiration “gold standard” assessing severity. Lung tests preschoolers are limited. Clinical respiratory scales may be useful...
Background. Information on atopic dermatitis (AD) epidemiology in preschool children is scarce. Objectives. To estimate the prevalence, clinical, allergological characteristics and risk factors of AD children. Materials methods. 5156 aged 3-6 years old living Altai Territory participated study. The study included a screening clinical phases. At stage prevalence was evaluated using Russian version ISAAC questionnaire, were additional questionnaire. diagnosis verified by allergists. Results....
The purpose of this work was to study NO-synthase gene polymorphic variants in term asthma occurrence. Clinical and functional characteristics with regards different were analyzed 250 asthmatic children aged 7 14 years under the 12-wk standard basic therapy for asthma. We used typical spectrum tests molecular genetic methods. Polymorphism at promotor region found be associated phenotype pathogenic features an important part inherited predisposition
Background. It is difficult to diagnose bronchial asthma (BA) in children under the age of 6 due limited ability study respiratory function. Therefore, it relevant search for such diagnostic markers BA that do not require active participation a child. Objective. Our aim was assess value serum periostin levels comparison with surrogate eosinophilic inflammation (total IgE and blood eosinophils) diagnosis preschool children. Methods. A cross-sectional included 3–6 years healthy peers. The...