A5101667753- MicroRNA in disease regulation
- Circular RNAs in diseases
- Hematopoietic Stem Cell Transplantation
- Pregnancy and preeclampsia studies
- ECG Monitoring and Analysis
- Virus-based gene therapy research
- Atrial Fibrillation Management and Outcomes
- Neurological Disease Mechanisms and Treatments
- Medical Imaging and Analysis
- Clostridium difficile and Clostridium perfringens research
- Advanced Control Systems Optimization
- Gut microbiota and health
- Reconstructive Surgery and Microvascular Techniques
- RNA modifications and cancer
- Pressure Ulcer Prevention and Management
- Cancer-related molecular mechanisms research
- Wound Healing and Treatments
- Retinoids in leukemia and cellular processes
- Advanced Neuroimaging Techniques and Applications
- Cancer therapeutics and mechanisms
- Diet and metabolism studies
- Acute Kidney Injury Research
- Mass Spectrometry Techniques and Applications
- RNA and protein synthesis mechanisms
- Pharmaceutical and Antibiotic Environmental Impacts
Guangzhou Medical University
2025
First Affiliated Hospital of Zhengzhou University
2013-2022
Zhengzhou University
2022
Nanyang Institute of Technology
2022
Binzhou People's Hospital
2018-2020
Henan University of Science and Technology
2014
Southern Medical University
2014
Nanfang Hospital
2014
Mackay Memorial Hospital
2011
Shanxi Medical University
2008
Background: The dysregulation of microRNAs has been implicated in the progression different malignancies. Herein, we sought to identify precise roles miR-155-5p cervical cancer. Materials and methods: expressions carcinoma cells clinical tissues were assessed using qRT-PCR analysis. functions on growth cancer cell investigated MTT colony formation. Transwell wound closure assays selected explore influence invasion migration cell. effect metastasis vivo was xenograft model experimental lung...
Despite advances in treatment, the prognosis for patients with high-risk pediatric solid tumors remains dismal. Tandem autologous stem cell transplantation (ASCT) offers promise improving outcomes these patients. This study aimed to examine efficacy and prognostic factors of tandem ASCT tumors. To determine survival undergoing ASCT. A total 40 treated from March 2015 August 2022 were included this retrospective study. The diagnoses neuroblastoma, germ tumors, atypical teratoid/rhabdoid...
MicroRNA (miR)-150 has been demonstrated to protect the heart from ischemic injury. However, protective effect of miR‑150 in hypoxia‑injured cardiomyocytes remains unclear. The present study aimed investigate target gene and underlying molecular mechanisms hypoxia‑induced cardiomyocyte apoptosis. Using hypoxia model human (HCMs) vitro, it was that markedly inhibited HCMs after treatment. Overexpressing significantly decreased HCM death In addition, GRP94 revealed be a direct miR‑150....
Abstract It has been reported microRNA‐301b (miR‐301b) was involved in the tumorigenesis of some cancers, but it not investigated cervical carcinoma yet. In this study, miR‐301b found significantly upregulated carcinoma, and patients with high expression had a shorter overall survival. When knocked down cells, cell growth could be abolished. Our further studies showed targeted RNF38, inhibited its cells. Moreover, RNF38 downregulated tissues negatively correlated expression. addition,...
In recent years, the death number of renal cell carcinoma (RCC) has been enhanced annually. The crucial function long non-coding RNA (lncRNA) in occurrence and progression cancer is great significance. However, specific role lncRNAs pathogenesis prognosis RCC not fully elucidated. Therefore, aim this study was to uncover lncRNA RP11-567G11.1 regulating RCC.Relative expression level tissues cells determined by quantitative Real Time-Polymerase Chain Reaction (qRT-PCR). influences on...
Objective To investigate the relationship between vertebral-basilar artery morphological abnormalities and posterior circulation infarction.Methods Eighty patients with infarction were chose as experimental group,100 non-posterior in same period control group,a case-control study was conducted,and changes two groups analyzed.Results There significant difference incidence of vertebral dominance,vertebral-basilar stenosis or occlusion group.Conclusions Vertebral-basilar are independent risk...
Objective To investigate the effect of hippocampal protection on neurological cognitive dysfunction caused by whole brain radiotherapy. Methods A total 98 patients received radiotherapy, 60 in protective hippocampus group and 38 conventional radiotherapy group. The difference neurocognitive impairment two grups was assessed using Montreal rating scale, benefit techniques. Results There no significant baseline overall score between whole-brain group, brath at 3, 6 12 months after...
Objective To investigate the influence of compound salvia injection on oxidative stress and complications in patients with gestational hypertension. Methods From August 2015 to Fabuary 2017, 140 hypertension Binzhou Central Hospital were selected as study objects, randomly divided into control group research according digital table, 70 cases each group.The was treated routine treatment, given treatment combined injection.After SOD, MDA, NO, HMGB1, Cys C, hs-CRP, TNF-α, blood pressure...
Abstract Background: The causative link between brain death and intestinal microbiota dysbiosis is unclear, the distortion in liver metabolism caused by requires further exploration. Methods: A rat model of was constructed sustained for 9 hours. Intestinal contents portal vein plasma were collected sequencing microbial metabolite detection. Liver tissue resected to investigate metabolic alterations, results compared with those a sham group. Results: Microbiota occurred at family genus levels...