- Dental Radiography and Imaging
- Advanced X-ray and CT Imaging
- Oral and Maxillofacial Pathology
- Bone health and treatments
- Bone Tumor Diagnosis and Treatments
- Radiation Dose and Imaging
- Endodontics and Root Canal Treatments
- Cancer Immunotherapy and Biomarkers
- Lung Cancer Treatments and Mutations
- Temporomandibular Joint Disorders
- Radiology practices and education
- Parathyroid Disorders and Treatments
- Medical Imaging Techniques and Applications
- Bone and Joint Diseases
- Cancer Diagnosis and Treatment
- Esophageal Cancer Research and Treatment
- Sinusitis and nasal conditions
- Orthodontics and Dentofacial Orthopedics
- Cancer-related Molecular Pathways
- Dental Implant Techniques and Outcomes
- Head and Neck Cancer Studies
- dental development and anomalies
- Vitamin D Research Studies
- Genetic Syndromes and Imprinting
- Cleft Lip and Palate Research
University of California, Los Angeles
2016-2025
Osaka University
2022
Oklahoma State University Center for Health Sciences
2017-2018
University of Connecticut
2003-2010
UConn Health
1998-2008
University of Liverpool
1990-1993
Aintree University Hospital
1990-1993
Walton Hospital
1990
The relationship between abnormal cell proliferation and aberrant control of hormonal secretion is a fundamental poorly understood issue in endocrine neoplasia. Transgenic mice with parathyroid-targeted overexpression the cyclin D1 oncogene, modeling gene rearrangement found human tumors, were created to determine whether primary defect this cell-cycle regulator can cause an serum calcium parathyroid hormone response, as typical hyperparathyroidism. We also sought develop animal model...
Mini-implant-assisted rapid palatal expansion (MARPE) appliances have been developed with the aim to enhance orthopedic effect induced by maxillary (RME). Maxillary Skeletal Expander (MSE) is a particular type of MARPE appliance characterized presence four mini-implants positioned in posterior part palate bi-cortical engagement. The present study evaluate MSE effects on midpalatal and pterygopalatine sutures late adolescents, using high-resolution CBCT. Specific aims are define magnitude...
Miniscrew-assisted rapid palatal expansion (MARPE) has been adopted in recent years to expand the maxilla late adolescence and adult patients. Maxillary Skeletal Expander (MSE) is a device that exploits principles of skeletal anchorage transmit force directly maxillary bony structures characterized by miniscrews' engagement nasal cortical bone layers. In literature, it reported zygomatic buttress major constraint hampers lateral movement maxilla, since located medially arches. The objective...
<h2>Abstract</h2><h3>Background</h3> The American Academy of Oral and Maxillofacial Radiology established an ad hoc committee to draft evidence-based recommendations clinical guidance for the application patient contact shielding during dentomaxillofacial imaging. <h3>Types Studies Reviewed</h3> reviewed monographs reports from radiation protection organizations studies that reported dose gonads, breasts, thyroid gland <h3>Results</h3> Considering absence radiation-induced heritable effects...
25-Hydroxyvitamin D (25D) circulates bound primarily to serum vitamin binding protein (DBP), with DBP showing higher affinity for 25D3 than 25D2. We therefore hypothesized that D2 (D2) promotes levels of unbound 25D (free 25D), different functional responses, relative D3 (D3). Week 3 C56BL/6 mice were placed on diets containing either or alone (both 1000 IU/kg). At week 8 and 16, had only 25D2 in circulation (26.6 ± 1.9 33.3 4.4 ng/mL), (28.3 2.0 31.7 2.1 ng/mL). (44.5 6.4 vs 62.4 11.6...
To examine the CT-imaging features of subjects with bacterial osteomyelitis (OM), osteoradionecrosis (ORN), and medication-related osteonecrosis jaw (MRONJ) histopathological confirmation, to diagnostic efficacy panoramic radiography MRI in detecting these disease features. 150 cases preoperative CT data were selected: 61 OM, 19 ORN, 70 MRONJ. 143 underwent X-ray examination, 47 MRI. The assessment criteria for imaging findings included: (1) bone resorption, (2) osteosclerosis, (3) clarity...
Candida albicans is a common opportunistic pathogen found in the oral mucosa. Clinical observations indicate significant positive association between carriage or infection and epithelial dysplasia/neoplasia. The aim of this study was to test whether C. able promote dysplasia carcinoma mouse model where carcinogen (4 Nitroquinoline 1-oxide [4NQO]) used as initiator neoplasia. Mice were divided into four groups: group 1 received 4NQO alone; 2 followed by (ATCC 90234); 3 vehicle dimethyl...
Abstract The cyclin D1 oncogene is frequently amplified/overexpressed in oral squamous cell carcinomas. Mice with overexpression of targeted to the stratified epithelia tongue, esophagus, and forestomach develop a phenotype epithelial dysplasia at these sites. In this study, we examined effect on susceptibility mice carcinogen‐induced tumorigenesis, using 4‐nitroquinoline‐1‐oxide (4NQO), an established potent carcinogen mice. Cyclin overexpressing nontransgenic littermates were administered...
Purpose: We sought to develop and characterize a model of human vitamin D nutritional insufficiency/deficiency in the adult mouse, which could have broad utility examining health consequences this common condition. Methods: Adult mice were fed diets containing cholecalciferol contents 0.05 IU/g, 0.25 0.5 IU/g or 1.5 for four months. studied induction steady-state insufficiency, its on primary metabolite levels, calcium homeostasis, parathyroid physiology, bone morphology. Results: All well...