Sridhar Ramachandran
A5048523541- Biomedical Text Mining and Ontologies
- Bioinformatics and Genomic Networks
- Genetics, Bioinformatics, and Biomedical Research
- Genomics and Phylogenetic Studies
- RNA and protein synthesis mechanisms
- Single-cell and spatial transcriptomics
- Semantic Web and Ontologies
- Gene expression and cancer classification
- Chromosomal and Genetic Variations
- Genomics and Chromatin Dynamics
- Zebrafish Biomedical Research Applications
- IoT-based Smart Home Systems
- Genomics and Rare Diseases
- Data Mining Algorithms and Applications
- CRISPR and Genetic Engineering
- Advanced Database Systems and Queries
- Embedded Systems Design Techniques
- EEG and Brain-Computer Interfaces
- Computational Drug Discovery Methods
- Data Quality and Management
- Video Coding and Compression Technologies
- Digital Filter Design and Implementation
- BRCA gene mutations in cancer
- Manufacturing Process and Optimization
- VLSI and FPGA Design Techniques
University of Oregon
2012-2025
Ramakrishna Mission Vidyalaya
2015-2023
University of Padua
2023
University College London
2023
SIB Swiss Institute of Bioinformatics
2023
Stanford University
2023
Phoenix Bioinformatics
2023
University at Buffalo, State University of New York
2023
University of Southern California
2023
JSS Medical College and Hospital
2022
Only a small proportion of the mouse genome is transcribed into mature messenger RNA transcripts. There an international collaborative effort to identify all full-length mRNA transcripts from mouse, and ensure that each represented in physical collection clones. Here we report manual annotation 60,770 complementary DNA sequences. These are clustered 33,409 'transcriptional units', contributing 90.1% newly established transcriptome database. Of these transcriptional units, 4,258 new...
RNAcentral is a comprehensive database of non-coding RNA (ncRNA) sequences that provides single access point to 44 resources and >18 million ncRNA from wide range organisms types. now also includes secondary (2D) structure information for >13 sequences, making the world's largest 2D database. The diagrams are displayed using R2DT, new visualization method uses consistent, reproducible recognizable layouts related RNAs. sequence similarity search has been updated with faster interface...
ZFIN, the Zebrafish Model Organism Database (http://zfin.org), is central resource for zebrafish genetic, genomic, phenotypic and developmental data. ZFIN curators manually curate integrate comprehensive data involving genes, mutants, transgenics, phenotypes, genotypes, gene expressions, morpholinos, antibodies, anatomical structures publications. Integrated views of these data, as well gathered through collaborations exchanges, are provided a wide selection web-based search forms. Among...
The Zebrafish Information Network (zfin.org) is the central repository for Danio rerio genetic and genomic data. has served zebrafish research community since 1994, expertly curating, integrating, displaying Key data types available at include, but are not limited to, genes, alleles, human disease models, gene expression, phenotype, function. makes Findable, Accessible, Interoperable, Reusable through nomenclature, curatorial annotation activities, web interfaces, downloads. Recently, 6...
The Alliance of Genome Resources (the Alliance) is a combined effort 7 knowledgebase projects: Saccharomyces Database, WormBase, FlyBase, Mouse the Zebrafish Information Network, Rat and Gene Ontology Resource. seeks to provide several benefits: better service various communities served by these projects; harmonized view data for all biomedical researchers, bioinformaticians, clinicians, students; more sustainable infrastructure. has cross-organism useful comparative views gene function,...
Abstract The Alliance of Genome Resources (Alliance) is an extensible coalition knowledgebases focused on the genetics and genomics intensively studied model organisms. organized as individual knowledge centers with strong connections to their research communities a centralized software infrastructure, discussed here. Model organisms currently represented in are budding yeast, Caenorhabditis elegans, Drosophila, zebrafish, frog, laboratory mouse, rat, Gene Ontology Consortium. project rapid...
ZFIN, the Zebrafish Model Organism Database, http://zfin.org , serves as central repository and web-based resource for zebrafish genetic, genomic, phenotypic developmental data. ZFIN manually curates comprehensive data genes, phenotypes, genotypes, gene expression, antibodies, anatomical structures publications. A wide-ranging collection of search forms tools facilitates access to integrated views these promoting analysis scientific discovery. Data represented in are derived from three...
The Zebrafish Information Network (ZFIN, http://zfin.org), the model organism database for zebrafish, provides central location curated zebrafish genetic, genomic and developmental data. Extensive data integration of mutant phenotypes, genes, expression patterns, sequences, genetic markers, morpholinos, map positions, publications community resources facilitates use as a studying gene function, development, behavior disease. Access to ZFIN is provided via web-based query forms through bulk...
The Zebrafish Model Organism Database (ZFIN; https://zfin.org) is the central resource for genetic, genomic, and phenotypic data zebrafish (Danio rerio) research. ZFIN continuously assesses trends in research, adding new types providing repositories tools that members of research community can use to navigate data. many advantages flexibility manipulation have made them an increasingly attractive animal model study human disease.To facilitate disease-related developed support provide disease...
The Zebrafish Information Network (ZFIN) (https://zfin.org/) is the database for model organism, zebrafish (Danio rerio). ZFIN expertly curates, organizes and provides a wide array of genetic genomic data, including genes, alleles, transgenic lines, gene expression, function, mutant phenotypes, orthology, human disease models, nomenclature reagents. New features at include increased support regions non-coding more expressive Gene Ontology annotations. has recently taken over maintenance...
The Zebrafish Model Organism Database (ZFIN; http://zfin.org) is the central resource for genetic and genomic data from zebrafish (Danio rerio) research. ZFIN staff curate detailed information about genes, mutants, genotypes, reporter lines, sequences, constructs, antibodies, knockdown reagents, expression patterns, phenotypes, gene product function, orthology publications. Researchers can submit mutant, transgenic, expression, phenotype directly to use Community Wiki share antibody protocol...
The Zebrafish Model Organism Database (ZFIN; http://zfin.org) is the central resource for zebrafish (Danio rerio) genetic, genomic, phenotypic and developmental data. ZFIN curators provide expert manual curation integration of comprehensive data involving genes, mutants, transgenic constructs lines, phenotypes, genotypes, gene expressions, morpholinos, TALENs, CRISPRs, antibodies, anatomical structures, models human disease publications. We integrate curated, directly submitted,...
Abstract The Zebrafish Information Network (ZFIN, zfin.org) is the database resource for genetic, genomic, and phenotypic data from research using zebrafish, Danio rerio. ZFIN curates information about genetic perturbations, gene expression, phenotype, function, human disease models zebrafish publications makes these available to researchers worldwide. Over past 20 years, have increasingly been used investigate effects of environmental exposures, becoming an ideal model study toxicity,...
The Zebrafish Information Network (ZFIN) (https://zfin.org/) is the database for model organism, zebrafish (Danio rerio). ZFIN expertly curates, organizes, and provides a wide array of genetic genomic data, including genes, alleles, transgenic lines, gene expression, function, mutant phenotypes, orthology, human disease models, nomenclature, reagents. New features at include major updates to home page page, two most used pages ZFIN. Data mutants function continue be contributed Alliance...
Danio rerio is a model organism used to investigate vertebrate development. Manipulation of the zebrafish genome and resultant gene products by mutation or targeted knockdown has made good system for investigating function, providing resource genetic contributors phenotype human disease. Phenotypic outcomes can be result mutation, products, manipulation experimental conditions, any combination thereof. Zebrafish have been in various chemical screens identify environmental disease outcomes....
Staphylococcus aureus is a common nosocomial pathogen with property to develop resistance antimicrobial agents. But in the modern era, drug had been developed by microbes due its continuous usage of antibiotics. This study was carried out evaluate antibiotic resistant pattern methicillin (MRSA) using molecular genotyping. In view present problem, has conducted detect genotyping mecA gene from MRSA and confirmation restriction sites EcoRI BamHI. The pus samples were swabbed out, clinical...
The Mouse Genome Sequencing Consortium and the RIKEN Exploration Research grouphave generated large sets of sequence data representing mouse genome transcriptome, respectively. These provide a valuable foundation for genomic research. challenges informatics community are how to integrate these with ever-expanding knowledge about roles genes gene products in biological processes, useful views scientific community. Public resources, such as National Center Biotechnology Information (NCBI;...
Abstract The zebrafish model organism database (ZFIN) provides a Web resource of genomic, genetic, developmental, and phenotypic data. ZFIN curates integrates data from current literature direct submissions laboratories. In addition, collaborates with other bioinformatics organizations to provide links relevant These can be accessed through variety Web‐based search display tools. This unit focuses on some the basic methods search, visualize, analyze data, including genes, gene expression,...