- Gastroesophageal reflux and treatments
- Dysphagia Assessment and Management
- Respiratory and Cough-Related Research
- Eosinophilic Esophagitis
- Voice and Speech Disorders
- Infant Health and Development
- Helicobacter pylori-related gastroenterology studies
- Gastrointestinal motility and disorders
- Parathyroid Disorders and Treatments
- Diet, Metabolism, and Disease
- Bladder and Urothelial Cancer Treatments
- Ferroptosis and cancer prognosis
- Tracheal and airway disorders
- Gastrointestinal disorders and treatments
- Facial Nerve Paralysis Treatment and Research
- Hip and Femur Fractures
- Obstructive Sleep Apnea Research
- Nasal Surgery and Airway Studies
- Esophageal and GI Pathology
- RNA modifications and cancer
- Neuroscience of respiration and sleep
- Biliary and Gastrointestinal Fistulas
- Circular RNAs in diseases
- Liver Disease Diagnosis and Treatment
- Congenital gastrointestinal and neural anomalies
Cell Technology (China)
2025
Tianjin Third Central Hospital
2025
Tianjin Medical University
2025
Tianjin Fire Research Institute
2025
Chinese PLA General Hospital
2022-2024
Anhui Medical University
2022-2023
Central South University
2022-2023
Affiliated Hospital of Guizhou Medical University
2023
Guiyang Medical University
2023
Xiangya Hospital Central South University
2022-2023
Abstract Background The triglyceride and glucose index (TyG) to high-density lipoprotein cholesterol ratio (TG/HDL-C) are substitute markers of insulin resistance (IR). In a retrospective cross-sectional study, the authors aimed compare efficacy two indicators in diagnosing metabolic-associated fatty liver disease (MAFLD) construct novel diagnosis model. Methods Overall, 229 patients (97 MAFLD 132 Non-MAFLD at West China Hospital Sichuan University were included. was diagnosed using...
Slow transit constipation is an intractable with unknown aetiology and uncertain pathogenesis. The gut microbiota maintains a symbiotic relationship the host has impact on metabolism. Previous studies have reported that some microbes ability to produce 5-hydroxytryptamine (5-HT), important neurotransmitter. However, there are scarce data exploiting effects of microbiota-derived 5-HT in constipation-related disease. We genetically engineered probiotic Escherichia coli Nissle 1917 (EcN-5-HT)...
<title>Abstract</title> <bold>Background</bold> Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by social communication deficits, restricted interests, and repetitive behaviors, often accompanied comorbidities such as epilepsy, sleep disturbances, gastrointestinal disorders (GIDs). The global prevalence of ASD has been steadily increasing, resulting in significant lifelong treatment costs substantial societal burdens, underscoring the urgent need for effective...
Objectives To compare the screening value of Reflux Symptom Score (RSS) and Index (RSI) for laryngopharyngeal reflux (LPR). Methods All included patients attending Department Otolaryngology at Sixth Medical Center PLA General Hospital from February 2022 to August 2022, completed RSS RSI underwent 24‐hour hypopharyngeal‐esophageal multichannel intraluminal impedance‐pH (24 h HEMII‐pH) monitoring. The results 24 HEMII‐pH were used as a diagnostic criterion LPR, consistency between two...
Bladder cancer (BLCA) is a heterogeneous disease, and there are many classical molecular subtypes that reflect tumor immune microenvironment (TME) heterogeneity but their clinical utility limited correct individual treatment prognosis cannot be predicted based on them. To find reliable effective biomarkers tools for predicting patients’ responses to several therapies, we developed new systemic indicator of vasculogenic mimicry (VM)–related genes mediated by the Xiangya cohort additional...
Abstract Objective To investigate the diagnostic value of symptom questionnaires, sign and combination 2 questionnaires for laryngopharyngeal reflux disease (LPRD). Study Design Prospective, single‐centered. Setting Seventy‐seven patients who were hospitalized in Department Otolaryngology–Head Neck Surgery from October 2022 to April 2023 included. Methods Included completed RSS, RSI, RSA, RFS underwent 24‐hour hypopharyngeal‐esophageal multichannel intraluminal impedance‐pH monitoring...
Objective To investigate the optimal time point for diagnosing laryngopharyngeal reflux (LPR) through combining 24‐h hypopharyngeal‐esophageal multichannel intraluminal impedance‐pH (24‐h HEMII‐pH) monitoring and multi‐time salivary pepsin test (MTPSPT). Study Design Prospective uncontrolled trial. Method Patients with without LPR symptoms were included as group control group, respectively. The patients in underwent HEMII‐pH MTPSPT. results of used a diagnostic criterion LPR, value tests...
Background Bladder carcinoma (BLCA) is a heterogeneous disease that makes it difficult to achieve proper individual treatment and predict prognosis. This study aimed develop risk score from new perspective of pyroptosis guide accurate prognosis prediction for BLCA. Methods The TCGA-BLCA cohort data were downloaded Cancer Genome Atlas database. Two external validation cohorts collected the Gene Expression Omnibus. Another independent (the Xiangya cohort) was recruited our hospital. least...
This study aimed to develop an objective and simple score for predicting the prognosis of patients with laryngeal contact granuloma (LCG) treated local glucocorticoid injection combined oral proton pump inhibitor (GI + PPI).
Objective To investigate the relationship between laryngopharyngeal reflux disease (LPRD) and gastroesophageal (GERD).
Abstract Objective To identify the characteristics of time‐point distribution occurrence hypopharyngeal‐proximal reflux episodes (HREs) in elderly and younger patients with laryngopharyngeal (LPR). Study Design Retrospective cohort study. Setting Analysis data from LPR‐related symptoms 24‑hour hypopharyngeal‐esophageal multichannel intraluminal impedance‐pH (24‐hour HEMII‑pH) monitoring February 2017 to September 2022 at Sixth Medical Center PLA General Hospital. Methods Patients were...
A peptic ulcer is a rare cause of distal common bile duct stricture, Obstructive jaundice as complication ulcerative duodenal stenosis quite difficult to differentiate from malignant disease, especially in those which esophagogastroduodenoscopy examination does not reveal an ulcer. In this case report, 61-year-old male suffered right upper quadrant pain, chills and fever caused by originating was treated surgically.
Objective To understand the mineral and bone disorder (MBD) status in maintenance hemodialysis (MHD) patients Anhui province; To explore risk factors of hyperphosphatemia. Methods The cases MHD were investigated centers 26 hospitals, including 19 tertiary seven secondary southern, northern central province from January 1st, 2014 to March 31st, 2014. Research content included general demographic characteristics, laboratory examination, clinical manifestation medications, etc. Taking...
Secondary hyperparathyroidism (SHPT) is a common complication in patients with end-stage renal disease and it also hemodialysis patients. SHPT can increase bone fragility calcification of blood vessels soft tissues, which greatly increases the risk death.