A5073931804- Microbial Community Ecology and Physiology
- Power Systems Fault Detection
- Aortic aneurysm repair treatments
- Plant Molecular Biology Research
- HVDC Systems and Fault Protection
- Plant Reproductive Biology
- Gut microbiota and health
- Soil Carbon and Nitrogen Dynamics
- Islanding Detection in Power Systems
- Genomics and Phylogenetic Studies
- Aortic Disease and Treatment Approaches
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- Child Nutrition and Water Access
- Plant Stress Responses and Tolerance
- Microbial Fuel Cells and Bioremediation
- Cancer-related molecular mechanisms research
- Poverty, Education, and Child Welfare
- Cancer Immunotherapy and Biomarkers
- Trace Elements in Health
- High-Voltage Power Transmission Systems
- Wastewater Treatment and Nitrogen Removal
- Plant tissue culture and regeneration
- RNA modifications and cancer
- Advanced Data Storage Technologies
Huazhong University of Science and Technology
2021-2025
Tongji Hospital
2021-2025
Zhongshan Hospital
2002-2025
Fudan University
2019-2025
South China Agricultural University
2021-2025
China Pharmaceutical University
2024-2025
Hebei University
2025
Shandong University
2020-2024
Tengzhou Central People's Hospital
2024
Zhongshan Hospital of Xiamen University
2024
Although high-throughput sequencing, such as Illumina-based technologies (e.g. MiSeq), has revolutionized microbial ecology, adaptation of amplicon sequencing for environmental community analysis is challenging due to the problem low base diversity.A new phasing approach (PAS) was developed by shifting phases among different samples from both directions via adding various numbers bases (0-7) spacers forward and reverse primers. Our results first indicated that PAS method substantially...
Micro-organisms play critical roles in many important biogeochemical processes the Earth's biosphere. However, understanding and characterizing functional capacity of microbial communities are still difficult due to extremely diverse often uncultivable nature most micro-organisms. In this study, we developed a new gene array, GeoChip 4, for analysing diversity, composition, structure, metabolic potential/activity dynamics communities. 4 contained approximately 82 000 probes covering 141 995...
Abstract Background Transmembrane receptor kinases play critical roles in both animal and plant signaling pathways regulating growth, development, differentiation, cell death, pathogenic defense responses. In Arabidopsis thaliana , there are at least 223 Leucine-rich repeat receptor-like (LRR-RLKs), representing one of the largest protein families. Although functional for a handful LRR-RLKs have been revealed, functions majority members this family not elucidated. Results As resource...
As one of the fundamental infrastructures for cloud computing, data center networks (DCN) have recently been studied extensively. We currently use pure software-based systems, FPGA based platforms, e.g., NetFPGA, or OpenFlow switches, to implement and evaluate various DCN designs including topology design, control plane routing, congestion control. However, approaches suffer from high CPU overhead processing latency; platforms are difficult program incur cost; focuses on functions at...
Abstract As two major forest types in the subtropics, broadleaved evergreen and deciduous forests have long interested ecologists. However, little is known about their belowground ecosystems despite ecological importance driving biogeochemical cycling. Here, we used Illumina MiSeq sequencing targeting 16S rRNA gene a microarray named GeoChip functional genes to analyse microbial communities soils of Shennongjia Mountain Central China, region as ‘The Oriental Botanic Garden’ for its...
The forest timberline responds quickly and markedly to climate changes, rendering it a ready indicator. Climate warming has caused an upshift of the worldwide. However, impact on belowground ecosystem biogeochemical cycles remain elusive. To understand soil microbial ecology timberline, we analyzed communities via 16s rRNA Illumina sequencing, microarray-based tool named GeoChip 4.0 random matrix theory-based association network approach. We selected 24 sampling sites at two vegetation belts...
Abstract Background Anthropogenic activities have increased the inputs of atmospheric reactive nitrogen (N) into terrestrial ecosystems, affecting soil carbon stability and microbial communities. Previous studies primarily examined effects deposition on taxonomy, enzymatic activities, functional processes. Here, we various traits communities how these are interrelated in a Mediterranean-type grassland administrated with 14 years 7 g m −2 year −1 N amendment, based estimated areas within...
The centromere proteins (CENPs), a critical mitosis-related protein complexes, are involved in the kinetochore assembly and chromosome segregation. In this study, we identified that CENPA was significantly up-regulated HCC highly expressed correlated with poor prognosis for patients. Knockdown of inhibited cell proliferation tumor growth vitro vivo. Mechanistically, transcriptionally activated cooperated YY1 to drive expression cyclin D1 (CCND1) neuropilin 2 (NRP2). Moreover, can be...
Brassinosteroids (BRs) are essential phytohormones regulating various developmental and physiological processes during normal growth development. cog1-3D (cogwheel1-3D) was identified as an activation-tagged genetic modifier of bri1-5, intermediate BR receptor mutant in Arabidopsis (Arabidopsis thaliana). COG1 encodes a Dof-type transcription factor found previously to act negative regulator the phytochrome signaling pathway. single mutants show elongated hypocotyl phenotype under light...
The ben1-1D (bri1-5 enhanced 1-1dominant) mutant was identified via an activation-tagging screen for bri1-5 extragenic modifiers. is a weak allele of the brassinosteroid receptor gene, BRI1. Overexpression BEN1 greatly enhances defective phenotypes plants. Removal by gene disruption in Col-0 wild-type background, on other hand, promotes elongation organs. Because encodes novel protein homologous to dihydroflavonol 4-reductase (DFR) and anthocyanidin reductase (BAN), probably involved...
• Genomic assay of sperm cell RNA provides insight into functional control, modes regulation, and contributions male gametes to double fertilization. Sperm cells rice (Oryza sativa) were isolated from field-grown, disease-free plants was processed for use with the full-genome Affymetrix microarray. Comparison Gene Expression Omnibus (GEO) reference arrays confirmed expressionally distinct gene profiles. A total 10 732 sequences detected in cells, which 1668 not expressed pollen or seedlings....
Abdominal aortic aneurysm (AAA) is a highly lethal cardiovascular disease that currently lacks effective pharmacological treatment given the complex pathophysiology of disease. Here, single-cell RNA-sequencing data from patients with AAA and mouse model are analyzed, which reveals pivotal pathological changes, including M1-like polarization macrophages loss contractile function in smooth muscle cells (SMCs). Both cell types express integrin αvβ3, allowing for their dual targeting single...
Corona effect is a critical factor in the design and construction of ultrahigh-voltage (UHV) transmission lines, since it can cause ionic wind, which induces destructive instability, such as conductor vibration rotation. Here, we develop 2-D unipolar ion discharge model by using electrohydrodynamic (EHD) methods coupled with Navier–Stokes (N–S) equations. The effects cross-sectional geometry voltage levels on distribution electric field, characteristics EHD force during corona have been...
Abstract Traditional imaging modalities used to monitor the diameter of aortic aneurysms (AAs) often fail follow pathological progression. Fibroblast activation protein (FAP), a key regulator extracellular matrix (ECM) remodeling, plays pivotal role in disease. However, its expression wall during aneurysm progression and potential correlation with disease severity remains unexplored. Here, utilizing histology levels FAP are higher patients AA compared healthy controls. In three distinct...
Introduction: Adoptive cell therapy (ACT) derived from autologous tumor-infiltrating lymphocytes (TIL) has demonstrated promising therapeutic efficacy in several cancers. However, its possible synergistic effects with anti-PD-1 advanced hepatocellular carcinoma (aHCC) remain unexplored. This study aims to investigate the of TIL infusion combined for aHCC. Case Presentation: Referring current protocol our clinical trial (NCT03658785), two patients HCC at BCLC stage C were enrolled receive...