Sachin Srinivasan

ORCID: 0000-0002-2250-5347
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About
Contact & Profiles
Research Areas
  • Gastric Cancer Management and Outcomes
  • Esophageal and GI Pathology
  • Esophageal Cancer Research and Treatment
  • Colorectal Cancer Screening and Detection
  • Helicobacter pylori-related gastroenterology studies
  • Gastroesophageal reflux and treatments
  • Cardiac Valve Diseases and Treatments
  • Biomedical and Engineering Education
  • Recycling and Waste Management Techniques
  • Eosinophilic Esophagitis
  • Medical Device Sterilization and Disinfection
  • COVID-19 and healthcare impacts
  • Healthcare cost, quality, practices
  • Gastrointestinal disorders and treatments
  • Pancreatic and Hepatic Oncology Research
  • Dysphagia Assessment and Management
  • Viral Infections and Immunology Research
  • Rheumatoid Arthritis Research and Therapies
  • Radiomics and Machine Learning in Medical Imaging
  • Diverticular Disease and Complications
  • Cardiac Fibrosis and Remodeling
  • Genetic factors in colorectal cancer
  • Cardiovascular Function and Risk Factors
  • Infection Control and Ventilation
  • Acute Ischemic Stroke Management

University of Kansas
2017-2024

University of Kansas Medical Center
2020-2024

Kansas City VA Medical Center
2020-2024

Medical University of Silesia
2024

All India Institute of Medical Sciences Jodhpur
2024

Motility (United States)
2022

Olathe Medical Center
2021

Wichita State University
2017-2021

Veterans Health Administration
2020-2021

Wichita Clinic
2020

Rationale : One-third of myocarditis cases progresses to dilated cardiomyopathy (DCM), but the mechanisms controlling this process are largely unknown. CD4 + T helper (Th)17 cells have been implicated in pathogenesis autoimmune diseases, role Th17-produced cytokines during inflammation-induced cardiac remodeling has not previously studied. Objective We examined importance interleukin (IL)-17A progression DCM using a mouse model. Methods and Results Immunization mice with myocarditogenic...

10.1161/circresaha.109.213157 article EN Circulation Research 2010-04-09

Objective Recent studies have suggested that fibromyalgia is inaccurately diagnosed in the community, and ~75% of persons reporting a physician diagnosis would not satisfy published criteria. To investigate possible diagnostic misclassification, we compared expert with Methods In university rheumatology clinic, 497 patients completed Multidimensional Health Assessment Questionnaire (MD‐HAQ) 2010 American College Rheumatology preliminary criteria modified for self‐administration during their...

10.1002/acr.23731 article EN Arthritis Care & Research 2019-02-06

Recently, some studies suggested that clinical diagnosis of fibromyalgia is inaccurate and does not reflect current definitions. However, this hypothesis has been tested. We examined whether was accurately diagnosed in the community.We surveyed 3276 primary care patients to determine status by criteria (CritFM). also determined had a physician's (MDFM) level symptom severity as measured polysymptomatic distress scale (PSD).The prevalence MDFM CritFM 6.1% (95% confidence interval [CI] 5.3%,...

10.1002/acr2.1006 article EN cc-by-nc ACR Open Rheumatology 2019-03-01

Abstract Background The COVID-19 pandemic has affected all people across the globe. Regional and community differences in timing severity of surges throughout can provide insight into risk factors for worse outcomes those hospitalized with COVID-19. Methods study cohort was derived from Cerner Real World Data (CRWD) Database made up patients proven infection December 1, 2019 through November 30, 2020. Baseline demographic information, comorbidities, hospital characteristics were obtained. We...

10.1186/s12879-022-07611-z article EN cc-by BMC Infectious Diseases 2022-07-29

Patients with gastroesophageal reflux (GERD) symptoms undergoing screening upper endoscopy for Barrett's esophagus (BE) frequently demonstrate columnar-lined epithelium, forceps biopsies (FBs) failing to yield intestinal metaplasia (IM). Repeat is then often necessary confirm a BE diagnosis. The aim of this study was assess the IM leading diagnosis by addition wide-area transepithelial sampling (WATS-3D) FB in patients GERD.

10.14309/ajg.0000000000002818 article EN The American Journal of Gastroenterology 2024-04-18

Nivolumab is a programmed cell death receptor (PD-1) inhibitor therapy for aggressive cancers; however, it poses risk of immune-related adverse side effects. We present 73-year-old male with renal carcinoma who developed myasthenia gravis (MG) after being treated nivolumab, proven by acetylcholine antibodies. Our patient presented symptoms fatigue and upper lower extremity weakness, eventually resulting in respiratory failure as result MG. an emerging advanced cancers but severe events....

10.7759/cureus.1702 article EN Cureus 2017-09-20

Abstract A third of myocarditis cases progress to dilated cardiomyopathy (DCM); however, the mechanisms controlling this process are largely unknown. Immunization BALB/c mice with myocarditogenic peptide in CFA adjuvant induced infiltration pathogenic IL-17A-secreting T helper type-17 cells into inflamed heart during acute stage; and mild-to-severe DCM chronic stage disease. However, IL-17A deficiency did not abrogate incidence or severity myosin-induced myocarditis, nor it ameliorate severe...

10.4049/jimmunol.184.supp.135.25 article EN The Journal of Immunology 2010-04-01
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