A5087195423- Thyroid and Parathyroid Surgery
- Parathyroid Disorders and Treatments
- Pituitary Gland Disorders and Treatments
- Adrenal and Paraganglionic Tumors
- Pleural and Pulmonary Diseases
- Bone health and treatments
- Neuroendocrine Tumor Research Advances
- Bone health and osteoporosis research
- Hormonal Regulation and Hypertension
- Medical Imaging and Pathology Studies
- Pneumothorax, Barotrauma, Emphysema
- Thyroid Cancer Diagnosis and Treatment
- Myasthenia Gravis and Thymoma
- Cancer Diagnosis and Treatment
- Vitamin D Research Studies
- Lung Cancer Diagnosis and Treatment
- Neuroblastoma Research and Treatments
- Tracheal and airway disorders
- Head and Neck Anomalies
- Trauma Management and Diagnosis
- Glioma Diagnosis and Treatment
- Sexual Differentiation and Disorders
- Sarcoma Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Peptidase Inhibition and Analysis
Carol Davila University of Medicine and Pharmacy
2010-2025
Clinical Emergency Hospital Bucharest
2004-2024
Iuliu Hațieganu University of Medicine and Pharmacy
2024
Institutul Național de Endocrinologie C.I. Parhon
2024
Ovidius University
2024
Thoracic Surgery Foundation
2023
Military University
2017
Spitalul Universitar de Urgenţă Militar Central Dr. Carol Davila
2009
Background: Teriparatide (TPT) acts against severe primary (postmenopausal) osteoporosis (MOP), and it requires continuation with another anti-resorptive drug to conserve or enhance the effects on fracture risk reduction. Objective: To analyse sequential pharmacotherapy in MOP who were treated upon a 24-month daily 20 µg TPT protocol (24-mo-TPT) followed by 12 months of drugs (12-mo-AR) amid real-life settings. Hypotheses: 1. candidates had more profile versus those did not fulfil criteria...
Type 2 diabetes mellitus (T2DM) and metabolic syndrome (MetS) are diseases caused by the interaction of genetic non-genetic factors. Therefore, aim our study was to investigate association between six common polymorphisms T2DM MetS in males. A total 120 T2DM, 75 MetS, healthy controls (HC) were included study. ACE ID, eNOS 4a/b, ATR1 A1166C, OXTR (A>G), SOD1 +35A/C, CAT-21A/T gene genotyped PCR or PCR-RFLP techniques. diagnosed at an earlier age compared (54 vs 55 years old, p=0.0003)...
Background and Clinical Significance: Granulomatosis with polyangiitis (GPA) represents a rare autoimmune disease granulomatous inflammation, tissue necrosis, systemic vasculitis of the small medium blood vessels. Although clinical elements vary, aortic involvement is exceptional it challenge that requires rapid intervention potential displaying fulminant evolution. Case Presentation: We report 64-year-old male an 18-year history GPA who presented atypical low back pain. Following ultrasound...
Background/Objective: Osteoporotic fractures may be prevalent, as expected, in patients with primary osteoporosis such menopause-related or age-related bone loss, but a supplementary contribution to the risk added by less than common conditions, including non-functioning adrenal tumor without mild autonomous cortisol secretion (MACS). Many of standard fracture risk-related elements are captured FRAX model; yet, novel insights brought an improved algorithm, namely, FRAXplus. Our objective was...
Background: Primary hyperparathyroidism (PHPT) represents a multi-faced disease with wide spectrum of manifestations. Familial forms PHPT (affecting up to 10% the cases) involve particular category that encompasses large range hereditary syndromes, including parathyroid hyper-function, frequently in setting multi-glandular disease. Objective: The aim was analyze most recent findings regarding multiple endocrine neoplasia type 2 (MEN2) better understanding timing respect associated ailments,...
Introduction: Pneumothorax is a condition that usually occurs in thin, young people, especially smokers. It an unusual complication of COVID-19 disease can be associated with worse results. This occur without pre-existing lung or mechanical ventilation. Materials and Methods: We present monocentric comparative retrospective study diagnostic treatment analysis two groups patients diagnosed non-COVID-19 pneumothorax. All included this underwent surgery thoracic department. The was conducted...
This narrative review comprehensively examines the impact of oxidative stress on military personnel, highlighting crucial role physical exercise and tailored diets, particularly ketogenic diet, in minimizing this stress. Through a meticulous analysis recent literature, study emphasizes how regular not only enhances cardiovascular, cognitive, musculoskeletal health but is also essential neutralizing effects stress, thereby improving endurance performance during long-term missions....
Primary cardiac tumours are relatively uncommon (75% benign). Across the other 25%, representing malignant neoplasia, sarcomas account for 75–95%, and primary intimal sarcoma (PCIS) is one of rarest findings. We aimed to present a comprehensive review practical considerations from multidisciplinary perspective with regard most recent published data in specific domain PCIS. covered issues awareness amid daily practice clinical presentation ultra-qualified management order achieve an adequate...
Background and Objectives: Malignant neoplasms are common causes of acute pleuropericardial effusion. Pleuropericarditis denotes poor patient prognosis, is associated with shortened average survival time, represents a surgical emergency. Materials Methods: We analyzed the impact two minimally invasive approaches, type cancer, other clinical variables on mortality 338 patients pleuropericarditis admitted to an emergency hospital in Romania between 2009 2020. All underwent surgeries prevent...
Polymeric nanoparticles have been introduced as a delivery vehicle for active compounds in broad range of medical applications due to their biocompatibility, stability, controlled release compounds, and reduced toxicity. The oral route is the most used approach biologics body. homeostasis function cavity tissues are dependent on activity stem cells. present work focuses, first time, interaction between two types polymeric nanoparticles, poly (lactic-co-glycolic acid) or PLGA PLGA/chitosan,...
A total of 1 out 10 patients with primary hyperparathyroidism (PHP) presents an underlying genetic form, such as multiple endocrine neoplasia types 1, 2A, etc., well hyperparathyroidism–jaw tumour syndrome (HJT). We aimed to summarise the recent data, thus raising more awareness regarding HJT, from clinical perspective PHP in association challenges and pitfalls CDC73 testing parafibromin staining. This narrative review included a sample-focused analysis past decade according PubMed search....
Background: Infective endocarditis (IE) is a pathological condition caused by various microbial agents that can lead to severe complications affecting the heart. Accurate diagnosis crucial for effective management of patients with IE. Blood culture gold standard identifying primary infectious agents, which key factor in diagnosing IE using modified Duke criteria. Objective: The main objective this study was investigate distribution etiological and most common secondary diagnoses associated...
Brown tumors, an exceptional bone complication of severe primary (PHP) or renal (secondary) hyperparathyroidism (RHP), are caused by long-standing, elevated parathormone (PTH)-induced osteoclast activation causing multinucleated giant cell conglomerates with hemosiderin deposits in addition to the local production cytokines and growth factors. We aim present adult case series including two females displaying this as part a multidisciplinary complex panel high PTH-related ailments. The...
Primary osteoporosis, a geriatric bone metabolic condition affecting both the mineral density and microarchitecture, comes with complex burden. Bone turnover markers tidily reflect changes of skeleton status that are part physiological process or theyhighlight abnormal including in osteoporosis addition to other biomolecules evaluation such as hormones, inflammatory markers, myokines adipokines. In this narrative review, we aimed highlight several aspects regarding osteoporosis-related...
Introduction: According to WHO, in worldwide cancer mortality statistics, the first place is occupied by bronchopulmonary cancer. This reason has led us carry out present pilot study, was with participation of Clinics Carol Davila University Medicine and Pharmacy Bucharest order apply a technique developed earlier Stefan-van Staden, for early detection this type cancer, initiate personalized diagnosis, implicitly treatment increase life expectancy among these patients. In recent years, there...
The present study constitutes a retrospective for patients with hyperparathyroidism surgically operated on at the Department of Thoracic Surgery Central Military Emergency University Hospital 'Dr. Carol Davila', Bucharest, Romania (SUUMC), over period 6 years. aimed to elucidate diagnostic and surgical attitude an effective treatment, practiced SUUMC, Romania. group included 55 patients: 41 women 14 men, diagnosed endocrinology department, who underwent various personalized surgeries (Kocher...