A5090777518- Drug Solubulity and Delivery Systems
- Advanced Drug Delivery Systems
- Analytical Methods in Pharmaceuticals
- Advancements in Transdermal Drug Delivery
- Curcumin's Biomedical Applications
- Hydrogels: synthesis, properties, applications
- Analytical Chemistry and Chromatography
- Essential Oils and Antimicrobial Activity
- Antibiotics Pharmacokinetics and Efficacy
- Nanoparticle-Based Drug Delivery
- Pharmaceutical studies and practices
- Metal complexes synthesis and properties
- Clay minerals and soil interactions
- Phytochemistry and Biological Activities
- Phytochemicals and Antioxidant Activities
- Nanocomposite Films for Food Packaging
- Advanced Polymer Synthesis and Characterization
- Synthesis and Characterization of Heterocyclic Compounds
- Pharmacological Effects of Natural Compounds
- Insect-Plant Interactions and Control
- Protein purification and stability
- Proteoglycans and glycosaminoglycans research
- Polysaccharides and Plant Cell Walls
- Inflammatory mediators and NSAID effects
- Synthesis and biological activity
Bahauddin Zakariya University
2016-2025
Islamia University of Bahawalpur
2025
Pakistan Agricultural Research Council
2018-2024
King Edward Medical University
2024
Jinnah Sindh Medical University
2020-2023
University of Karachi
2010-2021
Government College University, Faisalabad
2018-2020
University of Indonesia
2014-2020
Memorial Hospital
2020
Peterborough City Hospital
2020
The purpose of the study was to develop an SNEDDS improve solubility and bioavailability pitavastatin. pitavastatin in different oils, surfactants, co-surfactants determined a pseudo-ternary phase diagram constructed. characterized by zeta-sizer, zeta-potential, FTIR, DSC, TGA. Release permeation from studied for 12 24 h, respectively. lipolysis test, RBC lysis, effect on lipid profile, pharmacokinetics were studied. SPC3 formulation showed 104 ± 1.50 nm particle size, 0.198 polydispersity...
Complications of diabetic foot can be prevented using a naturally occurring, efficient, and newly synthesized antimicrobial agent. The purpose the study was to improve wound healing antibacterial effects quercetin its esterified complex with 4-formyl phenyl boronic acid (4FPBA-Q) compared phenytoin. formation 4FPBA-Q confirmed by thin-layer chromatography (TLC), Fourier transform infrared (FTIR) spectroscopy, mass spectrometry (MS). prepared used against Gram-positive bacteria along...
The present work aimed to develop nanoparticles of tobramycin (TRM) using thiolated chitosan (TCS) in order improve the mucoadhesion, antibacterial effect and pharmacokinetics. were evaluated for their compatibility, thermal stability, particle size, zeta potential, drug release, kinetics TRM corneal permeation, toxicity ocular irritation. thiolation was confirmed by 1H NMR FTIR, which showed peaks at 6.6 ppm 1230 cm-1, respectively. had a diameter 73 nm, negative potential (-21 mV)...
Members of the plant-specific B3-domain transcription factor family have important and varied functions, especially with respect to vegetative reproductive growth. Although B3 genes been studied in many other plants, there is limited information on genomic organization expression grapevine (Vitis vinifera L.). In this study, we identified 50 genome analyzed these terms chromosomal location syntenic relationships, intron–exon organization, promoter cis-element content. We also presumed...
Mucoadhesion is an important property that helps oral drug delivery system to remain attached with buccal mucosa and hence improve the of drug. The current study was designed achieve thiol modification Arabinoxylan (ARX) develop a mucoadhesive film for improved tizanidine hydrochloride (TZN HCl). Synthesis thiolated arabinoxylan (TARX) accomplished by esterification ARX thioglycolic acid (TGA). TARX further used development films which were prepared using solvent casting technique....
Aim of the present work was to develop alginate raft forming tablets for controlled release pantoprazole sodium sesquihydrate (PSS). Box behnken design used optimize 15 formulations with three independent and dependent variables. Physical tests all were within pharmacopoeial limits. Raft characterized by their strength, thickness, resilience, acid neutralizing capacity, floating lag time total time. thickness resilience optimized formulation AR9 7.43 ± 0.019 g, 5.8 0.245 cm greater than 480...
Thiomers are the polymers modified for mucoadhesive properties and other additive by incorporating thiol moieties in backbone of unmodified polymeric chain substitution reactions or simple oxidation reactions. Drugs that less soluble permeable can be complexed with thiomers their increased absorption through mucosal membranes increase contact time prolonged stay body due to mucoadhesion. Immobilization group therefore increases polymer 2–140-folds. The prepared characterized made stable...
The purpose of the study was to develop Tizanidine HCl (TZN) and Meloxicam (MLX) loaded bilayer mucoadhesive films intended for buccal administration, aiming enhance bioavailability. Bilayer were prepared by solvent evaporation technique selecting arabinoxylan (ARX) as a sustained release (SR) layer forming polymer hydroxypropyl methylcellulose (HPMC) E-15 an immediate (IR) layer-forming polymer. Prepared subjected in-vitro drug release, surface morphology, mechanical strength, compatibility...