A5000802682- Advanced Drug Delivery Systems
- Drug Solubulity and Delivery Systems
- Advancements in Transdermal Drug Delivery
- Analytical Methods in Pharmaceuticals
- Nanoparticle-Based Drug Delivery
- Clay minerals and soil interactions
- Hydrogels: synthesis, properties, applications
- Analytical Chemistry and Chromatography
- Pharmacological Effects of Natural Compounds
- Curcumin's Biomedical Applications
- Ocular Surface and Contact Lens
- Wound Healing and Treatments
- Therapeutic Uses of Natural Elements
- Antimicrobial agents and applications
- Oral and gingival health research
- Antibiotics Pharmacokinetics and Efficacy
- Iron oxide chemistry and applications
- Analytical Chemistry and Sensors
- Essential Oils and Antimicrobial Activity
- Tumors and Oncological Cases
- Advanced Polymer Synthesis and Characterization
- Complementary and Alternative Medicine Studies
- Textile materials and evaluations
- Bone Tissue Engineering Materials
- Electrospun Nanofibers in Biomedical Applications
Government College University, Faisalabad
2015-2025
University of the Punjab
2023
University of Gujrat
2022
University of Faisalabad
2021
Islamia University of Bahawalpur
2020
University of Sargodha
2020
Bahauddin Zakariya University
2016-2019
National Textile University
2015-2019
The present work aimed to develop nanoparticles of tobramycin (TRM) using thiolated chitosan (TCS) in order improve the mucoadhesion, antibacterial effect and pharmacokinetics. were evaluated for their compatibility, thermal stability, particle size, zeta potential, drug release, kinetics TRM corneal permeation, toxicity ocular irritation. thiolation was confirmed by 1H NMR FTIR, which showed peaks at 6.6 ppm 1230 cm-1, respectively. had a diameter 73 nm, negative potential (-21 mV)...
Wound-healing is complicated process that affected by many factors, especially bacterial infiltration at the site and not only need for regeneration of damaged tissues but also requirement antibacterial, anti-inflammatory, analgesic activity injured site. The objective present study was to develop evaluate natural essential oil-containing nanofiber (NF) mat with enhanced antibacterial activity, regenerative, non-cytotoxic, wound-healing potential. Clove oil (CEO) encapsulated in chitosan...
The purpose of the study was to develop an SNEDDS improve solubility and bioavailability pitavastatin. pitavastatin in different oils, surfactants, co-surfactants determined a pseudo-ternary phase diagram constructed. characterized by zeta-sizer, zeta-potential, FTIR, DSC, TGA. Release permeation from studied for 12 24 h, respectively. lipolysis test, RBC lysis, effect on lipid profile, pharmacokinetics were studied. SPC3 formulation showed 104 ± 1.50 nm particle size, 0.198 polydispersity...
Complications of diabetic foot can be prevented using a naturally occurring, efficient, and newly synthesized antimicrobial agent. The purpose the study was to improve wound healing antibacterial effects quercetin its esterified complex with 4-formyl phenyl boronic acid (4FPBA-Q) compared phenytoin. formation 4FPBA-Q confirmed by thin-layer chromatography (TLC), Fourier transform infrared (FTIR) spectroscopy, mass spectrometry (MS). prepared used against Gram-positive bacteria along...
Oral delivery, the most common method of therapeutic administration, has two significant obstacles: drug solubility and permeability. The challenges current oral medicine delivery are being tackled through an emerging that uses structures called polymeric micelles. In present study, micelles were developed using conjugates linoleic acid–carboxymethyl chitosan (LA-CMCS) for paclitaxel (PCL). evaluated by particle size, zeta potential, Fourier transform infrared spectroscopy (FTIR),...
The occurrence of fungal infections has increased over the past two decades. It is observed that superficial are treated by conventional dosage forms, which incapable treating deep due to barrier activity possessed stratum corneum skin. This why need for a topical preparation with advanced penetration techniques arisen. research aimed encapsulate fluconazole (FLZ) in novasome order improve delivery. novasomes were prepared using ethanol injection technique and characterized percent...
Aim of the present work was to develop alginate raft forming tablets for controlled release pantoprazole sodium sesquihydrate (PSS). Box behnken design used optimize 15 formulations with three independent and dependent variables. Physical tests all were within pharmacopoeial limits. Raft characterized by their strength, thickness, resilience, acid neutralizing capacity, floating lag time total time. thickness resilience optimized formulation AR9 7.43 ± 0.019 g, 5.8 0.245 cm greater than 480...
Garments made from cotton fabrics can readily absorb perspiration during strenuous activities but give poor performance in terms of wicking and evaporation the perspiration, resulting wet sticky feeling to wearer. The aim this study was investigate effect design method creating channels on moisture management air permeability fabrics. fabric specimens were printed with hydrophobic fluorocarbon finish using four different print designs, each two types printing squeegees. It found that both...
Depression is the major mental illness which causes along with loss of interest in daily life, a feeling hopelessness, appetite or weight changes, anger and irritability. Due to hepatic first-pass metabolism, absolute bioavailability fluvoxamine (FVM) after oral administration about 50%. By avoiding pre-systemic nasal delivery would boost FVM. Additionally, absorption anticipated occur more quickly than it via route because existence microvilli high vasculature. A nonionic surfactant,...
The most common female endocrinopathy, polycystic ovarian syndrome (PCOS), generally affects women of childbearing age. Hippophae rhamnoides L. has been traditionally used to improve menstrual cyclicity. Gas chromatography by flame ionization detection analysis showed that it contained various phytoconstituents such as omega-3 fatty acid, phytosterols, palmitic oleic and linoleic acid. H. (HR) nano-emulsion was also formulated. HR its encapsulated (HRNE) were evaluated for the treatment...
Nanofibers were prepared with different ratios of chitosan (CS) and polyethylene oxide (PEO) via the electrospinning technique, tested for morphological features using scanning electron microscopy (SEM). Drug content, drug loading, release moxifloxacin (MXF) at pH 4.7 5.5, degree swelling investigated. Further characterization was accomplished X-ray diffraction (XRD), thermogravimetric analysis (TGA) Fourier-transform infrared spectroscopy (FTIR). Antibacterial activity studied in comparison...
In the current research, attempt is made to fabricate a nanoemulsion (NE) containing an antifungal agent. The prepared formulation has been expected enhance skin penetration. It also studied for in vitro drug release and toxicity assessment. Spontaneous titration method was used preparation of NE. Prepared NE were characterized their charge, size, morphology, rheological behaviour, profile, permeability. permeation irritation investigated. activity inspected using well agar diffusion method....