A5081356178- Amyloidosis: Diagnosis, Treatment, Outcomes
- Parathyroid Disorders and Treatments
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Sarcoidosis and Beryllium Toxicity Research
- Cardiomyopathy and Myosin Studies
- Cardiac Valve Diseases and Treatments
- Heart Failure Treatment and Management
- Transplantation: Methods and Outcomes
- Peptidase Inhibition and Analysis
- Advanced MRI Techniques and Applications
- Cardiovascular Disease and Adiposity
- Chemotherapy-induced cardiotoxicity and mitigation
- Cardiac Structural Anomalies and Repair
- Atrial Fibrillation Management and Outcomes
- Coronary Artery Anomalies
- Cardiac tumors and thrombi
- Cardiac Arrhythmias and Treatments
- Infective Endocarditis Diagnosis and Management
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Chronic Myeloid Leukemia Treatments
- Aortic Disease and Treatment Approaches
- Cardiac electrophysiology and arrhythmias
- Viral Infections and Immunology Research
- Eosinophilic Disorders and Syndromes
University of Chicago
2021-2024
University of Chicago Medical Center
2022-2024
University of Illinois Chicago
2024
University of Virginia
2023-2024
University of Virginia Health System
2024
The Ohio State University
2020-2023
The Ohio State University Wexner Medical Center
2019-2023
University of California, Los Angeles
2023
Christ Hospital
2020
University of Michigan
2018
Abstract Aims Although impaired left ventricular (LV) global longitudinal strain (GLS) with apical sparing is a feature of cardiac amyloidosis (CA), its diagnostic accuracy has varied across studies. We aimed to determine the ability ratio (ASR) and most common echocardiographic parameters differentiate patients confirmed CA from those clinical and/or suspicion but this diagnosis ruled out. Methods results identified 544 200 controls (CTRLs) as defined above (CTRL patients). Measurements...
Assessment of left ventricular ejection fraction (LVEF) and global longitudinal strain (GLS) plays a key role in the diagnosis cardiac amyloidosis (CA). However, manual measurements are time consuming prone to variability. We aimed assess whether fully automated artificial intelligence (AI) calculation LVEF GLS provide similar estimates can identify abnormalities agreement with conventional methods, patients pre-clinical clinical CA.We identified 51 (age 80 ± 10 years, 53% male) confirmed CA...
Abstract To determine the differences in left atrial (LA) function and geometry assessed by cardiac magnetic resonance (CMR) between transthyretin (ATTR) immunoglobulin light chain (AL) amyloidosis (CA). We performed a retrospective analysis of 54 consecutive patients (68.5% male, mean age 67 ± 11 years) with confirmed CA (24 ATTR, 30 AL) who underwent comprehensive CMR examinations. LA structural functional assessment including volume, sphericity index, strain parameters were compared both...
While cardiac amyloidosis (CA) classically involves the left ventricle (LV), less is known about its impact on right (RV) and pulmonary vasculature. We performed a retrospective analysis to identify prevalence types of hypertension (PH) profiles in CA determine haemodynamic cardiovascular magnetic resonance (CMR) predictors major adverse events (MACE).Patients with who underwent CMR heart catheterisation (RHC) within 1 year between 2010 2019 were included. Patients assigned following based...
While transthoracic echocardiography (TTE) assessment of left ventricular end-diastolic pressure (LVEDP) is critically important, the current paradigm subject to error and indeterminate classification. Recently, peak atrial strain (LAS) was found be associated with LVEDP. We aimed test hypothesis that integration entire LAS time curve into a single parameter could improve accuracy in noninvasive LVEDP TTE.We retrospectively identified 294 patients who underwent heart catheterization TTE...
Abstract In cardiac amyloidosis (CA), amyloid infiltration results in increased left ventricular (LV) mass disproportionate to electrocardiographic (EKG) voltage. We assessed the relationship between LV mass–voltage ratio with subsequent heart failure hospitalization (HHF) and mortality CA. Patients confirmed CA comprehensive cardiovascular magnetic resonance (CMR) EKG exams were included. CMR-derived was indexed body surface area. voltage using Sokolow, Cornell, Limb–voltage criteria. The...
The optimal cardiovascular (CV) risk stratification in liver transplant (LT) candidates remains unclear. aim of this study was to evaluate concordance findings between dobutamine stress echocardiography (DSE), positron emission tomography/computed tomography myocardial perfusion imaging (PET/CT MPI), and left heart catheterization adult LT candidates.Data on 234 consecutive from February 2015 June 2018 with PET/CT MPI were reviewed. Adverse CV outcomes adjudicated via chart review by a...