A5055146656- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Dermatological and COVID-19 studies
- Viral Infections and Immunology Research
- Diagnosis and treatment of tuberculosis
- Inflammasome and immune disorders
- Tuberculosis Research and Epidemiology
- Cancer Immunotherapy and Biomarkers
- Infectious Diseases and Tuberculosis
- COVID-19 and healthcare impacts
Central Scientific Research Institute of Tuberculosis Russian Academy of Medical Sciences
2020-2022
Autopsy data from 80 patients who died of the COVID-19 infection were analysed. Using macro- and microscopic studies, specific features pathological processes in various organs identified. The obtained experimental data, along with information literature sources, allowed conclusions to be drawn about mechanisms damaging internal body systems, as well assumptions made individual links pathogenesis COVID-19. thanatogenesis disease main causes death are discussed, including acute...
Aim Despite the regular heart damage in patients with coronavirus pneumonia caused by SARS-Cov-2, a possibility of developing lymphocytic myocarditis as part COVID-19 remains unsubstantiated. The aim this study was to demonstrate and its morphological features novel infection (COVID-19) severe course. Material methods Postmortem data were studied for 5 elderly (74.8±4.4 years; 3 men 2 women) bilateral, polysegmental (stage 3–4 computed tomography). diagnosed based on typical clinical...
Despite a reported cardiac injury in patients with new coronavirus infection, the possibility and specifics of genuine viral myocarditis COVID-19 remains not fully clear.To study presence SARS-CoV-2 myocardium morphological properties severe infection (COVID-19).Autopsy data eight elderly (75.6 ± 7.4 years), four male female, were studied. The lifetime diagnosis is based on positive result PCR study. inclusion criterion was signs according to Dallas criteria. A standard histological...
Introduction. The pathogenesis of the novel coronavirus infection COVID-19 is being actively studied. Nevertheless, our up-to-date knowledge lymphoid tissue response in secondary immune organs dur-ing severe remains extremely limited. aim study was to evaluate patterns immu-nomorphological alterations lymph nodes patients with and assess lymphocytes functional activity them. Materials methods. Lymph node (autopsy material) from 17 deceased examined by histological immunohistochemical methods...
Материалом для исследования послужили данные 80 аутопсий пациентов, страдавших инфекцией COVID-19. При помощи макро- и микроскопического исследований продемонстрированы особенности патологических процессов в различных органах. Полученные сочетании со сведениями из литературы позволяют сделать выводы о закономерностях поражения внутренних органов систем организма, а также высказать предположения об отдельных звеньях патогенеза Обсуждается танатогенез при данном заболевании основные причины...
<b>Aim:</b> to study the severity of systemic inflammation in critically ill patients with COVID-19. <b>Materials and methods:</b> markers were studied 41 COVID-19 who died intensive care unit. We concentration C-reactive protein (CRP), procalcitonin (PCT), fibrinogen (P) albumin (A) blood sera number leukocytes (L). <b>Results:</b> It was found that levels CRP PCT increased all (100%) patients. Their average values significantly exceeded normal (CRP – 194,8±16,6 mg/l at a rate ≤10mg/l, p...