Aart J. van der Molen

ORCID: 0000-0002-2376-9424
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About
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Research Areas
  • Acute Kidney Injury Research
  • Radiation Dose and Imaging
  • MRI in cancer diagnosis
  • Lanthanide and Transition Metal Complexes
  • Advanced X-ray and CT Imaging
  • Advanced MRI Techniques and Applications
  • Medical Imaging Techniques and Applications
  • Chronic Kidney Disease and Diabetes
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Renal and Vascular Pathologies
  • Radiomics and Machine Learning in Medical Imaging
  • Cardiac Imaging and Diagnostics
  • Drug-Induced Adverse Reactions
  • Sarcoma Diagnosis and Treatment
  • Gastrointestinal Tumor Research and Treatment
  • Thyroid Disorders and Treatments
  • Radioactive element chemistry and processing
  • Radiology practices and education
  • Contact Dermatitis and Allergies
  • Restraint-Related Deaths
  • Venous Thromboembolism Diagnosis and Management
  • Pelvic and Acetabular Injuries
  • Cerebrospinal fluid and hydrocephalus
  • Advanced Neuroimaging Techniques and Applications

Leiden University Medical Center
2015-2024

Leiden University
2004-2024

Stanford University
2023

University of Wisconsin–Madison
2023

Cardiovascular Institute of the South
2023

Philips (Netherlands)
2023

Erasmus MC
2023

Università Campus Bio-Medico
2016-2017

Hôpital Paul-Brousse
2008

Assistance Publique – Hôpitaux de Paris
2008

Abstract Gadolinium-based contrast agents (GBCA) are essential for diagnostic MRI examinations. GBCA only used in small quantities on a per-patient basis; however, the acquisition of contrast-enhanced examinations worldwide results use many thousands litres per year. Data shows that these present sewage water, surface and drinking water regions world. Therefore, there is growing concern regarding environmental impact because their ubiquitous presence aquatic environment. To address problem...

10.1186/s13244-024-01626-7 article EN cc-by Insights into Imaging 2024-02-27

Modern iodinated contrast media (CM) consist of one or two tri-iodobenzene rings. They differ from each other in the composition side chains, creating different molecules and thus brand substances. After intravascular administration, all CM are distributed rapidly into extracellular fluids. eliminated solely by glomerular filtration. In patients with normal renal function, CMs within 24 h. The pathophysiology contrast-induced nephropathy (CIN) is based on three distinct but interacting...

10.1007/s13244-013-0291-3 article EN cc-by Insights into Imaging 2013-10-02

Purpose: Metal prostheses cause artifacts in computed tomography (CT) images. The purpose of this work was to design an efficient and accurate metal segmentation raw data achieve artifact suppression improve CT image quality for patients with hip or shoulder prostheses. Methods: technique incorporates two steps: object replacement the segmented region by new values using interpolation scheme, followed addition scaled signal intensity. Segmentation is performed directly sinograms, making it...

10.1118/1.3276777 article EN Medical Physics 2010-01-20

Purpose: To quantify the number of overrange rotations and to assess their relative contribution organ effective doses at 16-section body computed tomography (CT). Materials Methods: Overranging was quantified for four scanners by means free-in-air dose measurements different scan lengths. Overrange lengths a certain section width were derived all collimations clinically used pitches extrapolation. The effect reconstructed on overranging analyzed separately. Results applied clinical...

10.1148/radiol.2421051350 article EN Radiology 2007-01-01

To assess radiation exposure due to CT in the Netherlands.Twenty-one hospitals participated a dose survey for 21 most frequently used protocols. Hospitals completed Web with detailed parameters one patient per protocol, including length product (DLP) from scanner report. Only standard-sized patients (1.74 m and 77 kg BMI 25.4 kg/m(2) ± 15 %) each protocol available were considered. Effective (E) was estimated using ICRP-103-based E/DLP coefficients. Dose levels compared surveys other...

10.1007/s13244-013-0253-9 article EN cc-by Insights into Imaging 2013-05-14

<h3>Importance</h3> Prevention of postcontrast acute kidney injury in patients with stage 3 chronic disease (CKD) by means prehydration has been standard care for years. However, evidence the need this group is limited. <h3>Objective</h3> To assess renal safety omitting prophylactic prior to iodine-based contrast media administration CKD. <h3>Design, Setting, and Participants</h3> The Kompas trial was a multicenter, noninferiority, randomized clinical conducted at 6 hospitals Netherlands...

10.1001/jamainternmed.2019.7428 article EN JAMA Internal Medicine 2020-02-17

To reconstruct the first and last sections of a helical computed tomographic (CT) scan, scan length is automatically extended beyond planned image boundaries, phenomenon known as overranging. With common 16-section CT scanning protocols, overrange between 3 6 cm. For scanners with 64 or more sections, this will be much greater, since overranging increases pitch detector collimation increases. Manufacturers have equipped latest generation (128 more) dose-reducing innovations that reduce by...

10.1148/rg.304095167 article EN Radiographics 2010-07-01
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