A5052585650- Acute Kidney Injury Research
- Venous Thromboembolism Diagnosis and Management
- Pregnancy and preeclampsia studies
- Chronic Kidney Disease and Diabetes
- Atrial Fibrillation Management and Outcomes
- Renal and Vascular Pathologies
- Birth, Development, and Health
- Central Venous Catheters and Hemodialysis
- Neonatal Respiratory Health Research
- Diagnosis and Treatment of Venous Diseases
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Systemic Lupus Erythematosus Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Vascular Procedures and Complications
- Maternal and fetal healthcare
- Pregnancy and Medication Impact
- Cardiac Arrhythmias and Treatments
- Radiation Dose and Imaging
- Reproductive System and Pregnancy
- Cardiac Imaging and Diagnostics
- Blood Coagulation and Thrombosis Mechanisms
- Cardiac electrophysiology and arrhythmias
- Acute Myocardial Infarction Research
- Acute Ischemic Stroke Management
- Chemotherapy-related skin toxicity
University Medical Center Utrecht
2020-2025
Wilhelmina Children's Hospital
2018-2025
Erasmus MC
2024
Utrecht University
2020-2023
Leiden University Medical Center
2009-2020
VA Ann Arbor Healthcare System
2015
University of Michigan
2014-2015
Leiden University
2012-2014
Loyola University Medical Center
2009-2014
Beaumont Hospital, Royal Oak
2014
Objective The HAS-BLED score enables a risk estimate of major bleeds in patients with atrial fibrillation on vitamin K-antagonists (VKA) treatment, but has not been validated for venous thromboembolism (VTE). We analyzed whether the accurately identifies at high during VKA treatment acute VTE. Methods Medical records 537 VTE (primary diagnosis pulmonary embolism 223, deep vein thrombosis 314) starting between 2006-2007 were searched items and occurrence first 180 days follow-up. hazard ratio...
Transradial percutaneous coronary intervention (PCI [TRI]) does not involve catheter manipulation in the descending aorta, whereas transfemoral PCI (TFI) does. Therefore, risk of acute kidney injury (AKI) after might be influenced by vascular access site. We compared risks AKI and nephropathy requiring dialysis (NRD) among patients treated with TRI TFI.We included across 47 hospitals Michigan. Primary end point was (serum creatinine increase ≥0.5 mg/dL). Secondary points were NRD...
<h3>Importance</h3> Prevention of postcontrast acute kidney injury in patients with stage 3 chronic disease (CKD) by means prehydration has been standard care for years. However, evidence the need this group is limited. <h3>Objective</h3> To assess renal safety omitting prophylactic prior to iodine-based contrast media administration CKD. <h3>Design, Setting, and Participants</h3> The Kompas trial was a multicenter, noninferiority, randomized clinical conducted at 6 hospitals Netherlands...
Acute kidney injury (AKI) post percutaneous coronary intervention (PCI) is associated with increased mortality but both death and AKI share common risk factors. Moreover, the effect of a high contrast dose, known modifiable factor for AKI, on unknown. The aim our study was to analyze association between in-hospital PCI after adjustment confounding by factors.This performed using regional registry all patients undergoing in Michigan. Primary end points were (serum creatinine increase >0.5...
Although numbers of pregnancy after kidney transplantation (KT) are rising, high risks adverse outcomes (APO) remain. Though important for pre-conception counselling and monitoring, analyses KT per pre-pregnancy estimated glomerular filtration rate-chronic disease (eGFR-CKD)-categories have not been performed on a large scale before. To do this, we conducted Dutch nationwide cohort study consecutive singleton pregnancies over 20 weeks gestation KT. Outcomes were analyzed eGFR-CKD category...
Abstract Introduction Obesity is an increasing public health concern worldwide and can lead to more complications in pregnancy childbirth. Women with obesity often require induction of labor for various indications. The aim this study assess which method safest most effective women obesity. Material methods This a secondary analysis two randomized controlled trials about labor. term singleton cephalic presentation, unfavorable cervix, intact membranes without previous cesarean section were...
Guidelines recommend saline hydration for prophylaxis of contrast-induced acute kidney injury (CI-AKI) in patients with chronic disease (CKD) undergoing intravenous contrast media-enhanced CT (CE-CT). The safety and efficacy a brief protocol using sodium bicarbonate this population is unknown. We analysed whether 1-h prior to CE-CT non-inferior after CKD patients. performed an open-label multicentre randomized trial. Patients were 250 mL 1.4% or 1000 0.9% and, once again, CE-CT. Primary...
Essential information regarding efficacy and safety of vitamin K-antagonists (VKA) treatment for atrial fibrillation (AF) in non-dialysis dependent chronic kidney disease (CKD) is still lacking current literature. The aim our study was to compare the risks stroke or transient ischemic attack (TIA) major bleeds between patients without CKD (eGFR >60 ml/min), those with moderate 30-60 severe <30 ml/min).We included 300 CKD, 294 moderate, 130 who were matched age sex. Uni- multivariate Cox...
Background Prior studies have proposed to restrict the contrast volume (CV) <3x calculated creatinine clearance (CCC), prevent induced nephropathy (CIN) post percutaneous coronary interventions (PCI). The predictive value of this algorithm for CIN and therefore benefit approach in high risk patients has been questioned. aim our study was assess association between dose occurrence at varying predicted risks baseline CCC following contemporary PCI. Methods Consecutive undergoing PCI 2010–2012...
Background Transfusion is a common complication of Percutaneous Coronary Intervention (PCI) and associated with adverse short long term outcomes. There no risk model for identifying patients most likely to receive transfusion after PCI. The objective our study was develop validate tool predicting receipt blood in undergoing contemporary Methods Random forest models were developed utilizing 45 pre-procedural clinical laboratory variables estimate the influential selected inclusion an...