A5101641160- S100 Proteins and Annexins
- Neuroscience and Neuropharmacology Research
- Alzheimer's disease research and treatments
- Radio Astronomy Observations and Technology
- Cancer, Lipids, and Metabolism
- Cancer, Hypoxia, and Metabolism
- Plant tissue culture and regeneration
- Astrophysics and Cosmic Phenomena
- Bioactive Compounds and Antitumor Agents
- Plant-Microbe Interactions and Immunity
- bioluminescence and chemiluminescence research
- Computational Drug Discovery Methods
- Radio Wave Propagation Studies
- Cellular transport and secretion
- Phosphorus and nutrient management
- Receptor Mechanisms and Signaling
- Genetics and Neurodevelopmental Disorders
- Neuroinflammation and Neurodegeneration Mechanisms
- Chemical Synthesis and Analysis
- Photodynamic Therapy Research Studies
- Plant Pathogens and Resistance
- Soil and Water Nutrient Dynamics
- Plant Virus Research Studies
- Ruminant Nutrition and Digestive Physiology
- Cocoa and Sweet Potato Agronomy
Chinese Academy of Sciences
2003-2025
Chongqing Academy of Animal Science
2025
Shanghai Institute of Organic Chemistry
2021-2025
University of Chinese Academy of Sciences
2021-2025
Chengdu Institute of Biology
2024
National Astronomical Observatories
2021
Center for Excellence in Molecular Plant Sciences
2020-2021
Shanxi University
2021
The University of Texas Medical Branch at Galveston
2015
Oomycete pathogens such as Phytophthora secrete a repertoire of effectors into host cells to manipulate immunity and benefit infection. In this study, we found that an RxLR effector, Avr1d, promoted sojae infection in soybean hairy roots. Using yeast two-hybrid screen, identified the E3 ubiquitin ligase GmPUB13 target for Avr1d. By coimmunoprecipitation (Co-IP), gel infiltration, isothermal titration calorimetry (ITC) assays, confirmed Avr1d interacts with both vivo vitro. Furthermore,...
Phosphorus (P) pollution from livestock farming poses significant environmental challenges, necessitating efficient P utilization. This study systematically investigated the effects of varying dietary levels on growth, slaughter performance, nutrient digestion, and metabolism in Yunnan Semi-fine Wool Sheep during growth phase. Forty-five sheep (30.33 ± 0.56 kg) were randomly assigned to five (0.40, 0.51, 0.68, 0.82, 0.97%) over a 44-day trial, including 14-day pre-feeding 30-day formal trial...
Aβ is believed to play a significant role in synaptic degeneration observed Alzheimer’s disease (AD) and primarily investigated as secreted peptide. However, the contribution of intracellular or other cleavage products its precursor protein (APP) loss remains uncertain. In this study, we conducted systematic examination their cell-autonomous impact using sparse expression system. Here, these proteins/peptides were overexpressed single neuron, surrounded by thousands untransfected neurons....
Astrocytes play critical roles in brain development and disease, but the mechanisms that regulate astrocyte proliferation are poorly understood. We report is bi-directionally regulated by neuronal activity via NMDA receptor (NMDAR) signaling neurons. Prolonged treatment with an NMDAR antagonist reduced expression of cell-cycle-related genes astrocytes hippocampal cultures suppressed vitro vivo, whereas activation promoted proliferation, dependent on NMDARs. Expression...
An enhanced photodamaging ability towards CT-DNA was achieved in a tyrosine-modified hypocrellin B by improving the affinity of sensitizer to DNA.
Abstract Aβ is believed to play a significant role in synaptic degeneration observed Alzheimer’s disease (AD) and primarily investigated as secreted peptide. However, the contribution of intracellular or other cleavage products its precursor protein (APP) loss remains uncertain. In this study, we conducted systematic examination their cell-autonomous impact using sparse expression system. Here, these proteins/peptides were overexpressed single neuron, surrounded by thousands untransfected...
Aβ is believed to play a significant role in synaptic degeneration observed Alzheimer’s disease (AD) and primarily investigated as secreted peptide. However, the contribution of intracellular or other cleavage products its precursor protein (APP) loss remains uncertain. In this study, we conducted systematic examination their cell-autonomous impact using sparse expression system. Here, these proteins/peptides were overexpressed single neuron, surrounded by thousands untransfected neurons....
Aβ is believed to play a significant role in synaptic degeneration observed Alzheimer’s disease (AD) and primarily investigated as secreted peptide. However, the contribution of intracellular or other cleavage products its precursor protein (APP) loss remains uncertain. In this study, we conducted systematic examination their cell-autonomous impact using sparse expression system. Here, these proteins/peptides were overexpressed single neuron, surrounded by thousands untransfected neurons....
Abstract Oomycete pathogens such as Phytophthora secrete a repertoire of effectors to host cells manipulate immunity and benefit infection. In this study, we found that an RxLR effector, Avr1d, promoted sojae infection in soybean hairy-roots. Using yeast two-hybrid screen, identified the E3 ubiquitin ligase GmPUB13 target for Avr1d. By co-immunoprecipitation, gel infiltration ITC assays, confirmed Avr1d interacts with both vivo vitro . Furthermore, inhibits activity GmPUB13. The crystal...
A dedicated detection system has been proposed in this paper for probing Cosmic Dawn through measuring the 21cm global spectrum. wide-band antenna with low beam chromaticity developed system, real-time calibration a set of suits enable solution parameters and understanding performance. Preliminary results have obtained series testing observation radio quiet zone-Hongliuxia Station Xinjian province.
Exchange protein directly activated by cAMP (EPAC) is one of two intracellular receptors that mediate the effects prototypic second messenger cAMP. Identifying pharmacological probes for selectively modulating EPAC activity represents a significant unmet need within research field. In this study, we present thorough biochemical and characterization ESI‐09 based specific inhibitors, provide convincing evidence acts as an selective antagonist competing with binding, argue against notion...
Detection of the redshifted 21cm signal is a key to unlock mystery early cosmic evolution. The global from dawn era can be measured with single antenna. This achieved satellite on lunar orbit, where absence ionosphere and radio frequency interference (RFI) enables high precision measurement. We describe here design wide-band, frequency-independent disk-cone antenna for such satellite, which part orbit array Hongmeng project. In this paper we will focus science requirement, fabricating...