- Cardiac Health and Mental Health
- Suicide and Self-Harm Studies
- Tryptophan and brain disorders
- Bipolar Disorder and Treatment
- Hormonal Regulation and Hypertension
- Glioma Diagnosis and Treatment
- Neurofibromatosis and Schwannoma Cases
- Lipoproteins and Cardiovascular Health
- Heart Rate Variability and Autonomic Control
- Eating Disorders and Behaviors
- Gun Ownership and Violence Research
- Sarcoma Diagnosis and Treatment
- Cardiovascular Disease and Adiposity
- Stress Responses and Cortisol
- Cervical and Thoracic Myelopathy
- Clinical Reasoning and Diagnostic Skills
- Methemoglobinemia and Tumor Lysis Syndrome
- Soft tissue tumor case studies
- Restraint-Related Deaths
- Electrolyte and hormonal disorders
- Parasitic Infections and Diagnostics
- Cardiovascular Health and Risk Factors
- Hepatitis C virus research
- Oral and Maxillofacial Pathology
- Maternal Mental Health During Pregnancy and Postpartum
University of Iowa
2013-2025
University of Iowa Hospitals and Clinics
2023-2024
Carver Bible College
2019
The Jane Goodall Institute
2016
Objective To assess whether suicidal behavior during mixed states exceeds that expected from the manic or depressive components alone. Methods This study included 429 participants with bipolar disorder National Institute of Mental Health Collaborative Depression Study ( CDS ). Mood and were captured using Longitudinal Interval Follow‐up Evaluation Schedule Affective Disorders Schizophrenia. Suicidal each mood state, relative to euthymia, was analyzed Cox regression allow for repeated events,...
Background/Objectives: Pre-operative radiation (Pre-RT) decreases local recurrence following soft tissue sarcoma (STS) resection but carries the risk of wound healing complications (WHCs). This study evaluated skin specimens and clinical characteristics STS patients to (1) compare with without Pre-RT, (2) Pre-RT WHCs, (3) explore associations between WHCs. Methods: retrospective included 54 adults who underwent primary closure (Pre-RT n = 30). A pathologist was blinded outcomes...
Objective Anxious and depressive states are associated with increased cardiovascular disease (CVD) risk a proinflammatory phenotype, although the latter appears to be at least partially explained by adiposity. It was hypothesized that depression anxiety would elevated inflammation independent of adiposity in persons obesity high CVD. Methods This study explored relation between baseline as measured Beck Anxiety Inventory Depression Inventory‐II serum c‐reactive protein (CRP) cross‐sectional...
Objective We sought to determine the relationship between omega‐3 fatty acid content of red blood cell membranes (RBC), in particular docosahexaenoic (DHA) and eicosapentaenoic (EPA), baseline new‐onset depressive symptoms post‐menopausal women. secondarily characterize association dietary intake symptomatology. Methods Study participants included 7086 members Women's Health Initiative Memory (aged 63–81 years) who had an assessment RBC concentrations at screening visit. Depressive follow‐up...
Article AbstractObjective: The aim of this study was to characterize the relationship between serum low-density lipoprotein cholesterol (LDL-c) and subsequent depressive symptoms onset in postmenopausal women. We secondarily assessed high-density (HDL-c), total cholesterol, triglycerides.Method: This population-based prospective cohort utilizes data from 24,216 women 50 79 years age who were participants Women's Health Initiative, which originally ran 1993 2005 has since incorporated 2...
Previous research in bipolar disorder demonstrates greater than expected vascular dysfunction later the course of illness, proportionate to cumulative burden mood symptoms. However, little is known about effect acute states on function. Here we examine relation between function and state individuals with disorder.
The inflammatory marker C-reactive protein has been linked to anxiety across a number of studies. This paper uses data for 1,439 participants the National Health and Nutrition Examination Survey (NHANES) 1999-2004 examine association between (CRP), potential moderation by body mass index. No was found or depression CRP in unadjusted multivariable-adjusted logistic regression analyses, nor there evidence continuous BMI, BMI class, obesity. Future studies on relationship should utilize larger...
Abstract Methamphetamine is a psychostimulant that exerts its euphoric and stimulant effects by increasing cytosolic monoamine concentration at the nerve terminal. In addition to known systemic cardiovascular effects, there compelling evidence suggest direct neurotoxic effect of methamphetamine; however, existing body literature includes very few human tissue studies. This exploratory analysis used postmortem brain specimens examine histologic immunohistochemical features associated with...
Journal Article Ready, Set, Screen: The Role of the Clinical Laboratory in Eliminating Chronic Hepatitis B Infection Get access Jane E Persons, Persons Department Pathology, University Iowa Hospitals and Clinics, City, IA, United States https://orcid.org/0000-0002-2393-6886 Search for other works by this author on: Oxford Academic Google Scholar Anna Merrill Address correspondence to at: 200 Hawkins Dr., IA 52242, States. E-mail anna-merrill@uiowa.edu. https://orcid.org/0000-0002-5945-5937...
BACKGROUND Glioneuronal tumors (GNTs) comprise a rare class of central nervous system (CNS) neoplasms with varying degrees neuronal and glial differentiation that predominately affect children young adults. Within the current 2021 World Health Organization (WHO) classification CNS tumors, GNTs encompass 14 distinct tumor types. Recently, use whole-genome DNA methylation profiling has allowed more precise this group. OBSERVATIONS A 3-year-old male presented 3-month history increasing head...
Cervical spine manipulation is a known risk factor for vertebral artery dissection. In this report, we present case of fatal dissection that occurred as the result self-manipulation cervical spine. The decedent was 40-year-old man with no significant past medical history. He observed to "crack his neck" while at work. Soon after, he began experiencing neck pain, then developed strokelike symptoms and became unresponsive. transported local center, where imaging showed bilateral His...
Objectives. To examine sudden and unexpected or trauma-related deaths that occurred in the presence of law enforcement Johnson County, Iowa, between 2011 2020. Methods. We identified using definitions from National Association Medical Examiners. obtained data, including demographics, cause manner death, toxicology results, circumstances location event leading to comprehensive medical examiner investigative reports. Results. There were 165 enforcement: 114 a known disease, 51 either trauma...