A5025212361- Pancreatic and Hepatic Oncology Research
- Polyamine Metabolism and Applications
- Head and Neck Cancer Studies
- Viral gastroenteritis research and epidemiology
- Advanced Radiotherapy Techniques
- Hepatitis C virus research
- Breast Cancer Treatment Studies
- Hepatitis B Virus Studies
- Advances in Oncology and Radiotherapy
- Salivary Gland Tumors Diagnosis and Treatment
- Fungal Infections and Studies
- Radiomics and Machine Learning in Medical Imaging
- Cancer Genomics and Diagnostics
- Cancer Cells and Metastasis
- Parasitic Infections and Diagnostics
Wan Fang Hospital
2022-2024
Taipei Medical University
2022-2024
National Taiwan University
2008-2011
Pancreatic ductal adenocarcinoma (PDAC) is highly aggressive and has poor prognosis. There are few biomarkers to inform treatment decisions, collecting tumour samples for testing challenging.Circulating cells (CTCs) from patients with PDAC liquid biopsies were expanded ex vivo form CTC-derived organoid cultures, using a laboratory-developed biomimetic cell culture system. organoids tested sensitivity panel of nine drugs, tests conducted in triplicate, weighted cytotoxicity score (CTS) was...
Myb family transcription factors are important in regulating cell proliferation, differentiation, and cycle progression. Giardia lamblia differentiates into infectious cysts to survive outside of the host. During encystation, genes encoding cyst wall proteins (CWPs) coordinately induced. We have identified an encystation-induced Myb2 protein, which binds promoter regions cwp myb2 itself vitro. To elucidate role G. lamblia, we tested hypothesis that can activate genes. found overexpression...
Recurrences are frequent in nasopharyngeal carcinoma (NPC) despite high remission rates with treatment, leading to considerable morbidity. This study aimed develop a prediction model for NPC survival by harnessing both pre- and post-treatment magnetic resonance imaging (MRI) radiomics conjunction clinical data, focusing on 3-year progression-free (PFS) as the primary outcome. Our comprehensive approach involved retrospective MRI data collection of 276 eligible patients from three independent...
Background Antiviral therapy by nucleoside/nucleotide analogues (NAs) effectively reduces HBV replication in chronic hepatitis B (CHB) patients. Because long-term NA treatments will eventually select for drug- resistant mutants, early detection of mutants and frequent monitoring viral loads is crucial successful therapy. no efficient test one-tube quantification qualification various HBV-resistant exists, we propose to use high-resolution melting (HRM) analysis combination with real-time PCR...
This study evaluated dose differences in normal organs at risk, such as the lungs, heart, left anterior descending artery (LAD), right coronary artery, ventricle, and breast under personalized holder (PERSBRA), when using intensity-modulated radiation therapy (IMRT). protection offered by PERSBRA cancer therapy. Here, we retrospectively collected data from 24 patients with who underwent breast-conserving surgery well IMRT radiotherapy. We compared target coverage risk without PERSBRA. For...