A5089012129- Mosquito-borne diseases and control
- Viral Infections and Vectors
- Virology and Viral Diseases
- Infectious Encephalopathies and Encephalitis
- Autism Spectrum Disorder Research
- Malaria Research and Control
- Epilepsy research and treatment
- Child Nutrition and Water Access
- Cerebral Palsy and Movement Disorders
- Global Maternal and Child Health
- Metabolism and Genetic Disorders
- Retinal and Optic Conditions
- Neonatal and fetal brain pathology
- Cytomegalovirus and herpesvirus research
- Fish biology, ecology, and behavior
Universidade de Pernambuco
2016-2024
Centro de Tecnologias Estratégicas do Nordeste
2023
Hospital Universitário Oswaldo Cruz
2016-2021
Universidade Federal de Pernambuco
2020
London School of Hygiene & Tropical Medicine
2020
To report radiological findings observed in computed tomography (CT) and magnetic resonance imaging (MRI) scans of the first cases congenital infection microcephaly presumably associated with Zika virus current Brazilian epidemic.Retrospective study a case series.Association for Assistance Disabled Children (AACD), Pernambuco state, Brazil.23 children diagnosis during epidemic.Types abnormalities pattern lesions identified on CT MRI brain scans.Six 23 tested positive IgM antibodies to...
In 2015, a twenty-fold increase in the prevalence of microcephaly Brazil was reported, and Ministry Health associated this abnormal with maternal-fetal Zika virus (ZIKV) transmission.We assessed ophthalmological findings ten mothers their infants that had been clinically diagnosed ZIKV-related presented ocular abnormalities, born from May to December 2015.Seven (70.0%) referred symptoms during pregnancy (malaise, rash arthralgia), which six (85.7%) were first trimester. At time exam, no...
To describe the clinical, radiological, and electromyographic features in a series of children with joint contractures (arthrogryposis) associated congenital infection presumably caused by Zika virus.Retrospective case study.Association for Assistance Disabled Children, Pernambuco state, Brazil.Seven arthrogryposis diagnosis virus during Brazilian microcephaly epidemic.Main findings, likely correlation between clinical primary neurological abnormalities.The brain images all seven were...
Abstract Objective To estimate the incidence of epilepsy in children with Zika‐related microcephaly first 24 months life; to characterize associated clinical and electrographic findings; summarize treatment responses. Methods We followed a cohort children, born during 2015‐2016 Zika virus (ZIKV) epidemic Brazil, congenital evidence ZIKV infection on neuroimaging and/or laboratory testing. Neurological assessments were performed at ≤3, 6, 12, 15, 18, 21, life. Serial electroencephalograms...
The implications of congenital Zika Virus (ZIKV) infections for pediatric neurodevelopment and behavior remain inadequately studied. aim this study is to investigate patterns in groups children with differening severities ZIKV-related microcephaly prenatal ZIKV exposure the absence microcephaly.We conducted a cross-sectional study, nested cohort, 274 (aged 10-45 months) who were born during peak decline epidemic Northeast Brazil. Participants evaluated between February 2017 August 2019 at...
Background While Zika virus (ZIKV) is now widely recognized as a teratogen, the frequency and full spectrum of adverse outcomes congenital ZIKV infection remains incompletely understood. Methods Participants in MERG cohort pregnant women with rash, recruited from surveillance system December/2015-June/2017. Exposure definition was based on combination longitudinal data molecular, serologic (IgM IgG3) plaque reduction neutralization tests for ZIKV. Children were evaluated by team clinical...
Chikungunya virus is capable of affecting the nervous system children and adults. We describe a case sepsis encephalitis triggered by this agent in newborn whose mother developed symptoms acute infection 2 days before delivery. Consequently, infant had severe that evolved with postnatal-onset microcephaly, bilateral optic atrophy, epilepsy cerebral palsy.
Abstract The number of studies published on postnatal microcephaly in children with Congenital Zika Syndrome is small, clinical presentations vary and aspects the evolution these remain unclarified. present case series examined characteristics assessed growth velocity head circumference, weight height Z-scores 23 who developed during follow-up Microcephaly Epidemic Research Group Pediatric Cohort. To estimate change over time compare mean difference between sexes, we used multilevel...
To assess the longitudinal evolution of EEG findings in children with Zika related-microcephaly (ZRM) and to evaluate associations these patterns children's clinical neuroimaging characteristics.
Abstract Background: The implications of congenital Zika Virus (ZIKV) infections for pediatric neurodevelopment and behavior remain inadequately studied. aim this study is to investigate patterns in children with different levels ZIKV-related microcephaly or prenatal ZIKV exposure the absence microcephaly. Methods: We conducted a cross-sectional study, nested cohort, 274 (aged 10-45 months) who were born during peak decline epidemic Northeast Brazil. Participants evaluated between February...
<title>Abstract</title> <bold>Objective:</bold> To describe the feeding characteristics and growth of children with prenatal exposure to Zika virus (ZIKV) from birth 48 months. <bold>Design: </bold>Using data prospective Microcephaly Epidemic Research Group Pediatric Cohort (MERG-PC), without microcephaly born mothers evidence ZIKV infection during pregnancy (ZIKV-exposed microcephaly) Zika-related were compared using repeated cross-sectional analyses within following age strata: birth; 1...
Case presentation: A 11-month-old female patient with Trisomy 21 (Down Syndrome) who developed infantile spasms at 6-months-old. She was diagnosed West Syndrome and first treated Vigabatrin (VGB). positive response observed, control of the spams regression hypsarrhythmia electroencephalogram register. well controlled until 10-months-old, when returned developmental regression. treatment synthetic adrenocorticotropic hormone (ACTH) started in a low dose, but partial spasms. It decided to...
Abstract Background: The implications of congenital Zika Virus (ZIKV) infections for pediatric neurodevelopment and behavior remain inadequately studied. aim this study is to investigate patterns in groups children with differening severities ZIKV-related microcephaly prenatal ZIKV exposure the absence microcephaly. Methods: We conducted a cross-sectional study, nested cohort, 274 (aged 10-45 months) who were born during peak decline epidemic Northeast Brazil. Participants evaluated between...
Abstract Background The implications for pediatric neurodevelopment and behavior remain sparsely studied in children exposed to congenital infection by Zika Virus (ZIKV). aim of this study is compare patterns with different levels Zika-related microcephaly or prenatal exposure without microcephaly. Methods A Cross-sectional nested a cohort, including 274 aged 10–45 months. Participantes were evaluated between Feb/2017 Aug/2019 two tertiary care hospitals Recife/Pernambuco/Brazil. Primary was...
Abstract Background: The implications of congenital Zika Virus (ZIKV) infections for pediatric neurodevelopment and behavior remain inadequately studied. aim this study is to investigate patterns in groups children with differening severities ZIKV-related microcephaly prenatal ZIKV exposure the absence microcephaly. Methods: We conducted a cross-sectional study, nested cohort, 274 (aged 10-45 months) who were born during peak decline epidemic Northeast Brazil. Participants evaluated between...