A5047392577- Advanced biosensing and bioanalysis techniques
- Supramolecular Self-Assembly in Materials
- RNA Interference and Gene Delivery
- Genetic and phenotypic traits in livestock
- Mechanical Behavior of Composites
- Ruminant Nutrition and Digestive Physiology
- Hypothalamic control of reproductive hormones
- Meat and Animal Product Quality
- Circular RNAs in diseases
- Cancer-related gene regulation
- Medical Imaging and Pathology Studies
- RNA modifications and cancer
- Immune Response and Inflammation
- Ubiquitin and proteasome pathways
- Heme Oxygenase-1 and Carbon Monoxide
- Berberine and alkaloids research
- Paraquat toxicity studies and treatments
- MicroRNA in disease regulation
- Receptor Mechanisms and Signaling
- Synthesis and Biological Activity
- Hormonal and reproductive studies
- Structural Load-Bearing Analysis
- Structural Analysis and Optimization
- Cancer-related molecular mechanisms research
Hong Kong Polytechnic University
2023
Shanghai Jiao Tong University
2001-2022
Shanghai Ninth People's Hospital
2022
State Key Laboratory of Oncogene and Related Genes
2014
Shanghai Cancer Institute
2014
Renji Hospital
2014
Background: Toll-like receptor 9 (TLR9), an important component of the innate immune system, contributes to pathogenesis lung injury. However, its role in paraquat (PQ)-induced injury has not been studied. Method: Mice were divided into PQ group ( n = 24) and control 12). both groups killed on either day 7 or 28 after (40 mg/kg intraperitoneally) saline administration. TLR9 expression was evaluated through real-time polymerase chain reaction immunohistochemistry. Concurrently,...
Cast in place liquid shim is usually used to fix the gap/mismatch problems, which occur during assembly process of large aircraft structures. The effect on performances assembled structures influenced not only by thickness and mechanical properties shim, but also location where used, that say stiffness substrates may have impact shim’s effect. To study usage composite-to-titanium bolted joints, a three-dimensional finite element method introduced, incorporates progressive damage composite...
Abstract Synthetic messenger RNA (mRNA) switches are powerful tools for in situ cell purification, especially cells derived from stem cells. However, the retention effectiveness of target is limited by leaky expression toxic protein. The elimination efficiency non‐target also constrained due to lack signal amplification. In this study, we designed a novel approach that uses synthetic mRNA switch convey intracellular marker molecule information into spatially controlled extracellular assembly...
The biological activity of testosterone is thought to occur predominantly through binding the androgen receptor (AR), a member nuclear superfamily that functions as ligand-activated transcription factor. Here, we found could induce rapid rise in intracellular free Ca2+ concentration ([Ca2+]i) Fura-2 loaded bone marrow-derived macrophages (BMMs), which was be due influx extracellular Ni2+-blockable channels plasma membrane. However, these effects not associated with classical AR BMMs, since...
Synthetic messenger RNA (mRNA) switches are powerful tools for in situ cell purification, especially cells derived from stem cells. However, the retention effectiveness of target is limited by leaky expression toxic protein. The elimination efficiency non-target also constrained due to lack signal amplification. In this study, we designed a novel approach that uses synthetic mRNA switch convey intracellular marker molecule information into spatially controlled extracellular assembly...