A5019476343- Plant-Microbe Interactions and Immunity
- Hemoglobin structure and function
- Plant Virus Research Studies
- Physiological and biochemical adaptations
- Plant Stress Responses and Tolerance
- Insect Resistance and Genetics
- Transgenic Plants and Applications
- Polar Research and Ecology
- Erythrocyte Function and Pathophysiology
- Wheat and Barley Genetics and Pathology
- Toxin Mechanisms and Immunotoxins
- Mass Spectrometry Techniques and Applications
- Enzyme Structure and Function
- Advanced Proteomics Techniques and Applications
- Amino Acid Enzymes and Metabolism
- Protein Structure and Dynamics
- Plant Gene Expression Analysis
- High Altitude and Hypoxia
- Plant Parasitism and Resistance
- Protein Hydrolysis and Bioactive Peptides
- Legume Nitrogen Fixing Symbiosis
- Fungal Biology and Applications
- Photosynthetic Processes and Mechanisms
- Insect-Plant Interactions and Control
- Plant pathogens and resistance mechanisms
University of Missouri
2021-2025
Institute for Sustainable Plant Protection
2024
National Research Council
2024
University of Buenos Aires
2024
Consejo Nacional de Investigaciones Científicas y Técnicas
2024
Università degli Studi della Tuscia
2014-2023
Universidade de São Paulo
2015-2022
University of Catania
2021
Penn State Milton S. Hershey Medical Center
2016-2021
Geisinger Medical Center
2019
The amino acid sequence of the glucose transport protein from human HepG2 hepatoma cells was deduced analysis a complementary DNA clone. Structural purified erythrocyte transporter by fast atom bombardment mapping and gas phase Edman degradation confirmed identity clone demonstrated that transporters are highly homologous may be identical. lacks cleavable amino-terminal signal sequence. Analysis primary structure suggests presence 12 membrane-spanning domains. Several these form amphipathic...
Sex differences in the incidence of respiratory diseases have been reported. Women are more susceptible to inflammatory lung disease induced by air pollution and show worse adverse pulmonary health outcomes than men. However, mechanisms underlying these remain unknown. In present study, we hypothesized that sex expression mediators affect sex-specific immune responses environmental toxicants. We focused on effects ground-level ozone, a major pollutant, regulation immunity genes. exposed...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThermostable NAD+-dependent alcohol dehydrogenase from Sulfolobus solfataricus: gene and protein sequence determination relationship to other dehydrogenasesSergio Ammendola, Carlo A. Raia, Carla Caruso, Laura Camardella, Sabato D'Auria, Mario De Rosa, Mose RossiCite this: Biochemistry 1992, 31, 49, 12514–12523Publication Date (Print):December 15, 1992Publication History Published online1 May 2002Published inissue 15 December...
PR4 proteins possess antifungal activity against several pathogenic fungi suggesting a pivotal role in defence reactions plant pathogen attack. We already showed that wheatwin1, wheat PR protein of class 4, is endowed with ribonuclease activity. In this study we produced three mutants altering the active site and performed comparative analysis native also presence inhibitor 5′‐ADP. characterized RNA binding its interaction 5′‐ADP by 3D modelling docking studies. Moreover, vitro assays have...
In plant defense, priming is a physiological process by which prepares to more quickly or aggressively respond future biotic abiotic stress. This unique state can be induced beneficial microbes treatment with natural synthetic compounds. Priming has been described copiously, mainly in dicots, but the study on molecular mechanisms regulating phenomenon still at its infancy. A fascinating possibility that epigenetic changes may main actors establishment. accessible chromatin structure, due DNA...
The role of jasmonates in defense priming has been widely recognized. Priming is a physiological process by which plant exposed to low doses biotic or abiotic elicitors activates faster and/or stronger responses when subsequently challenged stress. In this work, we investigated the impact MeJA-induced mechanical wounding rice (Oryza sativa). proteome reprogramming plants treated with MeJA, MeJA+wounding in-depth analyzed using combination high throughput profiling techniques and...
Abstract Plant roots can exploit beneficial associations with soil-inhabiting microbes, promoting growth and expanding the immune capacity of host plant. In this work, we aimed to provide new information on changes occurring in tomato interacting fungus Beauveria bassiana. The leaf proteome revealed perturbed molecular pathways during establishment plant–fungus relationship. early stages colonization (5–7 d), proteins related defense responses were down-regulated calcium transport...
We have demonstrated that wheatwin1, a wheat pathogenesis‐related protein of class 4 (PR4), has ribonuclease activity. Both native and recombinant proteins hydrolyse RNA from coleoptils antifungal Sepharose‐bound wheatwin1 is able to interact with either or Fusarium culmorum RNA. 3D modelling studies showed that, like ribonucleases A T1, the action mechanism should involve two His residues, an Arg residue Asp residue.
Resistance conferred by biotrophic pathogens often requires salicylic acid (SA) signaling, whereas necrotrophic or wounding mainly activate the jasmonate/ethylene (JA/ET)-dependent pathway. Crosstalk connections between these two independent signaling pathways may lead to synergistic antagonistic behavior. In order shed some light on crosstalk hormones in Arabidopsis plants, a proteomic approach combined with transcriptomic analysis has been used identify molecules differentially expressed...
ABSTRACT Background Endobronchial ultrasound guided Transbronchial Needle Aspiration (EBUS‐TBNA) is the predominant method for investigation of centrally located solitary pulmonary nodules. The associated with good to excellent diagnostic sensitivity and specificity positive predictive value test reaching 100% reported negative values FNA nodules ranging from 53% 97%. impact correlating cytologic results imaging clinical findings improvement has been poorly studied. Materials Methods An...
Human fetal mesenchymal stem cells (hfMSCs) present advantageous characteristics compared to their adult counterparts and have emerged as potent in the field of regenerative medicine. In context skeletal regeneration, human amniotic fluid (AFSCs) been shown improve quality structure bone extracellular matrix an experimental model severe osteogenesis imperfecta. However, primary hfMSCs undergo replicative senescence during vitro expansion, along with a progressive decrease plasticity tissue...
A trypsin inhibitor from wheat kernel (WTI) was found to have a strong antifungal activity against number of pathogenic fungi and inhibit fungal trypsin‐like activity. WTI inhibited in vitro spore germination hyphal growth pathogens, with protein concentration required for 50% inhibition (IC 50 ) values ranging 111.7 above 500 μg/ml. As observed by electron microscopy, determined morphological alterations represented branching. One the species tested, Botrytis cinerea produced protease,...
Antarctic fish of the family Nototheniidae usually have a single major hemoglobin (Hb 1), often second, minor component 2, about 5% total), and traces another C, less than 1%). These are functionally similar Bohr Root effect hemoglobins. All species other highly endemic families so far investigated also one hemoglobin. The hematological features nototheniid Trematomus newnesi remarkably different. It is only in which Hb 1 2 display very weak no effect. Perhaps consequentially, C (the showing...