A5070060381- Child and Adolescent Psychosocial and Emotional Development
- Schizophrenia research and treatment
- Bipolar Disorder and Treatment
- Attention Deficit Hyperactivity Disorder
- Autism Spectrum Disorder Research
- Genetics and Neurodevelopmental Disorders
- Suicide and Self-Harm Studies
- Tryptophan and brain disorders
- Adolescent and Pediatric Healthcare
- Psychosomatic Disorders and Their Treatments
- Diet and metabolism studies
- Childhood Cancer Survivors' Quality of Life
- Psychopathy, Forensic Psychiatry, Sexual Offending
- Personality Disorders and Psychopathology
- Obsessive-Compulsive Spectrum Disorders
- Neurological disorders and treatments
- Diabetes and associated disorders
- Family and Disability Support Research
- Child Development and Digital Technology
- Diabetes Treatment and Management
- COVID-19 and Mental Health
- Mental Health Research Topics
- Psychiatry, Mental Health, Neuroscience
- Metabolism and Genetic Disorders
- Attachment and Relationship Dynamics
University of Bari Aldo Moro
2016-2025
The Sense Innovation and Research Center
2014
Ospedale Pediatrico Giovanni XXIII
2013
Paroxysmal dyskinesias are episodic movement disorders that can be inherited or sporadic in nature. The pathophysiology underlying these remains largely unknown but may involve disrupted ion homeostasis due to defects cell-surface channels nutrient transporters. In this study, we describe a family with paroxysmal exertion-induced dyskinesia (PED) over 3 generations. Their PED was accompanied by epilepsy, mild developmental delay, reduced CSF glucose levels, hemolytic anemia echinocytosis,...
Recent studies support several overlapping traits between autism spectrum disorders (ASD) and attention-deficit/hyperactivity disorder (ADHD), assuming the existence of a combined phenotype. The aim our study was to evaluate common or distinctive clinical features ASD ADHD in order identify possible different phenotypes that could have value. We enrolled 181 subjects divided into four diagnostic groups: group, ASD+ADHD group (that met criteria for both ADHD), control group. Intelligent...
Autism Spectrum Disorder (ASD) has historically been studied, known, and diagnosed in males. Females tend to remain unidentified, especially those with average intelligence abilities. This sex/gender difference might be partially explained by biological risk factors, but it is probably also bound methodological issues. The present study aims examine phenotypic characteristics (cognitive, emotive, socio-communicative, academic) of a group 54 females ASD matched 55 males (3–18 years), all...
Non-suicidal self-injury (NSSI) is a transdiagnostic behavior often found in patients with eating disorders (EDs). Both conditions plateau adolescence and share psychopathological traits. Our study focuses on body image concerns, complex construct associated both NSSI ED, as shared risk factor between the two. This included 73 participants aged 14-24 recruited from Eating Disorders Day Hospital, University Hospital of Bari, Italy, divided into two groups: those an ED (ED + NSSI) without...
Over the last few years, new studies focused their attention on gender-related features in high-functioning autism spectrum disorder (HFA), often leading to controversial results. Another interesting aspect of these subtype patients is linked complexity clinical presentation, where besides core symptoms, other co-occurrence disorders may complicate diagnostic evaluation. Therefore, we retrospectively studied 159 HFA patients, male and female, investigating comorbidities find any gender...
Objective Young people moving from child and adolescent mental health services (CAMHS) to adult (AMHS) are faced with significant challenges. To improve this state of affairs, there needs be a recognition the problem initiatives an urgent requirement for appropriate tools measuring readiness outcomes at transfer boundary (16–18 years age in Europe). The objective study was develop validate Transition Readiness Appropriateness Measure (TRAM) assessing young person’s transition, their...
Vitamin D plays a role in central nervous system (CNS) development. Recent literature focused on vitamin status children and adolescents with autism spectrum disorder (ASD), but inconsistent results. Our case-control study is aimed at evaluating serum 25-hydroxyl-vitamin (25(OH)D) concentration ASD (ASD group, n = 54) compared to affected by other neurological psychiatric disorders (non-ASD 36). All patients were admitted the Complex Operative Unit of Child Neuropsychiatry, Polyclinic Bari,...
Non-suicidal self-injury (NSSI) is a significant public health issue that particularly affects female adolescents usually emerging during puberty, with subsequent reduction and even remission in the phenomenon later life. The dysregulation of hormonal stress response, cortisol dehydroepiandrosterone sulfate (DHEA-S), whose levels increase markedly pubertal adrenarche, has been associated development maintenance wide range emotional disorders. Our study aims to investigate whether different...
Objective: An association between streptococcal infections, ABGA positivity, and no comorbidity ADHD (nc-ADHD) has been little investigated. The aim of this study was to evaluate the infection frequency, defined entitled serum antistreptolysin O (ASO), frequency positivity in a sample patients with nc-ADHD. Method: In all 40 participants were investigated ASO titer ABGA. Results: results showed that statistically significantly higher affected by than control group, pathological values more...
Recurrent headache is common in childhood, but there not a great amount of data on the associations between headaches and psychopathology children.The aim this study to examine relationships primary children, using both categorical dimensional assessment.The sample consisted 70 patients with compared matched 50 healthy children. Psychiatric comorbidity was defined according diagnostic criteria Diagnostic Statistical Manual Disorders. Child outcomes were assessed child- parent-reported...
The aim of this prospective observational study was to verify the tolerability and safety profile risperidone in a sample antipsychotic-naive children/adolescent patients having different psychiatric diagnosis. Twenty-two (mean age 12±3.2) who started therapy with were recruited. assessment involved anthropometric data (weight, height, BMI, BMI z-score percentile), cardiovascular parameters (blood pressure QTc interval) blood tests (levels glucose, triglycerides, total cholesterol, glutamic...
The aim of this prospective observational study was to investigate the variations serum prolactin hormone (PRL) in a sample 34 drug-naive patients (mean age 13 years) who started risperidone therapy assuming that several factors may favor increase PRL. Serum PRL and hyperprolactinemia clinical signs were examined at baseline (T0) after almost 3 months treatment (T1). We considered sex, pubertal status, dosage, psychiatric diagnosis, any personal/family history autoimmune diseases. mean value...
Despite the growing interest in a dimensional approach to assessment of symptoms and clinically relevant phenomena schizophrenia spectrum disorders, very few studies, date, have examined structure early onset first episode psychosis. In present study, we assessed sample 60 children adolescents both sexes with A principal component analysis (PCA) Positive Negative Syndrome Scale (PANSS) was performed factors obtained were used carry out cluster analysis. Sex, age before or after 13, markers...
Hyperprolactinemia and glucose lipid metabolism abnormalities are often found in patients with schizophrenia generally considered secondary to the use of antipsychotic drugs. More recent studies have shown these same neuroendocrine metabolic naïve first episode psychosis (FEP), rising hypothesis that itself may be related an abnormal regulation prolactin secretion impaired tolerance. The aim this study was compare levels, glycometabolism parameters profile between a sample 31 drug-naive...
Depressive disorders (DDs) and non-suicidal self-injury (NSSI) are important juvenile mental health issues, showing alarming increasing rates. They frequently co-occur, mainly among adolescents, the suicide risk. We aimed to compare clinical features of two groups adolescents with DDs, differed by their engagement or not in NSSI ("DD + NSSI" "DD"). hypothesized that would characterize particularly severe forms DDs suitable for becoming specific phenotypes adolescent depression. enrolled 56...