A5063124897- Climate Change and Health Impacts
- Air Quality and Health Impacts
- Heavy Metal Exposure and Toxicity
- Heme Oxygenase-1 and Carbon Monoxide
- Arsenic contamination and mitigation
- Environmental Justice and Health Disparities
- Environmental and Social Impact Assessments
- Heavy metals in environment
- Energy and Environment Impacts
- Burn Injury Management and Outcomes
- Health and Conflict Studies
- Global Public Health Policies and Epidemiology
- Health Systems, Economic Evaluations, Quality of Life
- Neonatal Health and Biochemistry
- Public Health Policies and Education
- Disaster Response and Management
- LGBTQ Health, Identity, and Policy
- Pharmacovigilance and Adverse Drug Reactions
- Viral Infections and Vectors
- Groundwater and Isotope Geochemistry
- Health disparities and outcomes
- Public health and occupational medicine
- Intramuscular injections and effects
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Data-Driven Disease Surveillance
National Institute for Health Research
2023-2025
Imperial College London
2012-2025
UK Health Security Agency
2022-2024
Public Health England
2014-2020
Services Australia
2020
Didcot Community Hospital
2016-2018
European Centre for Disease Prevention and Control
2013-2017
Centre for Sight
2017
Crabbe Consulting
2016
Monash University
2015
Abstract Private water supplies (PWS) in Cornwall, South West England exceeded the current WHO guidance value and UK prescribed concentration or (PCV) for arsenic of 10 μg/L 5% properties surveyed ( n = 497). In this follow-up study, first its kind UK, volunteers 207) from 127 households who used their PWS drinking, provided urine drinking samples total As determination by inductively coupled plasma mass spectrometry (ICP-MS) urinary speciation high performance liquid chromatography ICP-MS...
Chronic exposure to arsenic (As) in drinking water is an established cause of cancer and other adverse health effects.
Accidental non-fire-related (ANFR) carbon monoxide (CO) poisoning is a cause of fatalities and hospital admissions. This the first study that describes characteristics ANFR CO admissions in England. Hospital Episode Statistics (HES) inpatient data for England between 2001 2010 were used. defined as any mention ICD-10 code T58: toxic effect X47: accidental by gases or vapours, excluding codes potentially related to fires (X00-X09, T20-T32 Y26). There 2463 over 10-year period (annual rate:...
Exposure to arsenic (As) via residential soil and dust is a global concern, in regions affected by mining or with elevated concentrations present underlying geology. Cornwall south west England one such area. Residential (n = 127) household 99) samples were collected from across as part of wider study assessing exposure environmental As. Samples analysed for total As (soil samples) human ingestion bioaccessible properties home-grown produce). Arsenic ranged 12 992 mg kg-1 3 1079...
Background . Potential exposure to carbon monoxide (CO) in private homes is largely unquantified. Aim To estimate prevalence of potential CO residential dwellings and describe associated interventions an inner-city community. Methods A housing association London, Hackney Homes, began fitting alarms the 22,831 local authority it responsible for January 2010. gas engineer investigated each alarm activation recorded information on a standard form. We undertook cross-sectional study all homes,...
Recent cases of acute kidney injury due to Seoul hantavirus infection from exposure wild or pet fancy rats suggest this is increasing in prevalence the UK. We conducted a seroprevalence study England estimate cumulative at-risk groups with contact domesticated and assess risk inform public health advice. From October 2013 June 2014, 844 individual blood samples were collected. Hantavirus amongst rat owner group was 34.1% (95% CI 23·9-45·7%) compared 3·3% 1·6-6·0) baseline control group, 2·4%...
There is increasing appreciation of the proportion health burden that attributed to modifiable population exposure environmental hazards. To manage this avoidable in United Kingdom (UK), government policies and interventions are implemented. In practice, procedure interdisciplinary action multi-dimensional context. Here, we demonstrate how Multi Criteria Decision Analysis (MCDA) can be used as a decision support tool facilitate priority setting for public within local authorities. We combine...
Context: Epidemiological preparedness is vital in providing relevant, transparent, and timely intelligence for the management, mitigation, prevention of public health impacts following major environmental incidents. A register a set records containing systematically collected, standardized data about individual people. Planning people affected by or exposed to an incident one evolving tools response arsenal. Objective: We compared contrasted instigation design registers epidemiological...
Over the last two centuries, nature of healthcare and public health has evolved from infectious disease control sanitation to issues surrounding 7-fold population growth emerging threats associated with chronic non-communicable diseases (NCDs), global climate change, pollution diminishing resources.1 Knowledge is needed support a range sectors that contribute prevention management NCDs, such as transportation, housing, energy, waste management, land use change. The physical environment...
Unintentional non-fire related (UNFR) carbon monoxide (CO) poisoning continues to cause fatalities. The narrative verdicts from coroners concerning fatal UNFR CO in England and Wales, 1998-2019, were collated by the Office for National Statistics. Search terms exposure used obtain information regarding circumstances of death. Findings grouped location death, source CO, reason or behaviour underlying exposure. There 750 deaths (77% male). annual number decreased over period studied. Two...
The mouse Pactolus gene is an evolutionary paralogue to the CD18/beta2 integrin subunit and preferentially expressed by neutrophils. When first identified, it was assumed would function as adhesion receptor similar other beta subunits. analysis of mice genetically deficient in Pactolus, however, did not define any lesion neutrophil migration, or phagocytosis. Therefore a wider deficiency initiated using transcriptional profiling during inflammatory insult. This screen identified single...
Approximately one million people in the UK are served by private water supplies (PWS) where main municipal supply system connection is not practical or PWS preferred option. Chronic exposure to contaminants may have adverse effects on health. South West England an area with elevated arsenic concentrations groundwater and over 9000 domestic dwellings here supplied PWS. There remains uncertainty as extent of population exposed (As), factors predicting such exposure. We describe a hazard...
Dust elemental levels can be expressed as concentrations (bulk samples) or surface loadings (wipe samples).
Abstract Background Children incur lead toxicity even at low blood-lead concentrations (BLCs), and testing in England is opportunistic. We described epidemiology of cases notified to a passive laboratory-based surveillance system (SS), the Lead Poisoning (LPIC) SS inform opportunities prevent exposure children England. Methods Surveillance population: <16 years age resident during reporting period September 2014–17. Case definition: with BLC ≥0.48 μmol/l (10 μg/dl). extracted case...
Introduction: The preventable environmental burden of disease estimated for the UK is 14%. To support primary prevention non-communicable disease, robust information leading to actions that reduce hazard exposures required, could an public health service and a Health in All Policies approach. In England, no comprehensive population-based surveillance exists integrates information. Public England (PHE) decided develop Environmental Surveillance System (EPHSS), with first phase build...
Exposure to lead can harm a child's health, including damage the nervous system, delayed growth, hearing loss, and many other adverse health effects, as well implications for social, economic, educational social well-being. Lead exposure in children is still concern cases require public management find source interrupt pathway. Housing characteristics indicate presence of lead-contaminated paint leaded water supply pipes. We aimed explore relationship between housing elevated blood...