A5035584184- Gastric Cancer Management and Outcomes
- Cancer-related molecular mechanisms research
- Helicobacter pylori-related gastroenterology studies
- MicroRNA in disease regulation
- Gastrointestinal Tumor Research and Treatment
- Enhanced Recovery After Surgery
- Lung Cancer Diagnosis and Treatment
- Metastasis and carcinoma case studies
- Esophageal Cancer Research and Treatment
- Physiological and biochemical adaptations
- Plant and Biological Electrophysiology Studies
- Planarian Biology and Electrostimulation
- bioluminescence and chemiluminescence research
- Circular RNAs in diseases
- Reproductive biology and impacts on aquatic species
- Ferroptosis and cancer prognosis
- Extracellular vesicles in disease
- Acupuncture Treatment Research Studies
- Occupational and environmental lung diseases
- Neonatal Respiratory Health Research
- Cancer Immunotherapy and Biomarkers
- Respiratory and Cough-Related Research
- Aquaculture Nutrition and Growth
- Methemoglobinemia and Tumor Lysis Syndrome
- Gastroesophageal reflux and treatments
Second Affiliated Hospital of Zhejiang University
2018-2024
Ruijin Hospital
2024
Yunnan Normal University
2022-2024
Zhejiang Chinese Medical University
2024
First Affiliated Hospital of Anhui Medical University
2023
Anhui Medical University
2023
Hangzhou Medical College
2023
Zhejiang Provincial People's Hospital
2023
Zhejiang University
2018-2022
Federal University Dutse
2022
Objectives To investigate sex difference in global gastric cancer incidence by year, age and socioeconomical status. Design An international comparative study. Setting We obtained the national sex-specific of caner year from Global Burden Disease Study 2017. The human development index (HDI) 2017 as an indicator status was extracted Human Development Report. Main outcome measures Sex-specific compared at level. Linear regression analyses were performed to explore socioeconomic-associated...
Colorectal cancer (CRC) is one of the most commonly diagnosed cancers with an estimated 1.8 million new cases worldwide and associated high mortality rates 881 000 CRC-related deaths in 2018. Screening programs therapies have only marginally improved survival CRC patients. Immune-related genes (IRGs) attracted attention recent years as therapeutic targets. The aim this study was to identify immune-related prognostic signature for CRC. To end, we combined gene expression clinical data from...
Abstract Postoperative venous thromboembolic events (VTEs), such as lower extremity deep vein thrombosis (DVT), are major risk factors for gastric cancer (GC) patients following radical gastrectomy. Accurately predicting and managing these risks is crucial optimal patient care. This retrospective case‒control study involved 693 GC from our hospital who underwent We collected plentiful comprehensive clinical indicators including a total of 49 baseline, preoperative, surgical pathological...
Abstract This paper synthesizes and extends the literature on multivariate two-part regression modelling, with an emphasis actuarial applications. To illustrate we use data from US Medical Expenditure Panel Survey to explore expenditures that come in two parts. In first part, zero correspond no payments for health care services during a year. For second positive expenditure corresponds payment amount, measure of utilization. Expenditures are multivariate, five components being (i)...
Cancer-associated fibroblasts (CAFs) aggravate gastric cancer (GC) development.Combined with bioinformatics analysis and literature review, miR-223-3p had high expression in microvesicles (MVs) derived from GC CAFs, it could modulate SORBS1. SORBS1 mRNA levels were assessed by qRT-PCR. The of CAFs markers, MVs epithelial-mesenchymal transition (EMT)-associated proteins, protein western blot. isolated observed transmission electron microscopy. Combined immunofluorescence co-culture...
Abstract Background Thyroid carcinoma (TC) is the most common malignancy of endocrine system. Circular RNA (circRNA) vital in regulation tumor progression. Circ_0000144 serves as a novel oncogenic circRNA, and miR‐217 reported to inhibit malignant phenotypes cancer cells by targeting AKT3 TC. The present study aimed explore regulatory mechanism circ_0000144 progression Methods expression 32 pairs TC tissues different cell lines (including BCPAP, K1, H7H83, TPC‐1) was detected employing...
Gastrointestinal stromal tumors (GISTs), with a primary occurrence in the duodenum and proximal jejunum, are rare treatment is poorly understood. This study aimed to evaluate main factors influencing prognosis of GIST resection this complex anatomical structure.This retrospective included 47 patients who underwent surgery for (20) jejunum (27) between 2012 2017. Perioperative clinical data as well relapse survival information were collected.All negative margin (R0) duodenal GISTs....
NOTCH receptor 3 (NOTCH3) is known to regulate the transcription of oncogenes or tumor suppressor genes, thereby playing a crucial role in development, invasion, maintenance, and chemotherapy resistance. However, specific mechanism how NOTCH3 drives immune infiltration gastrointestinal cancer remains uncertain. The expression was analyzed through Western blot, PCR, Oncomine database, Tumor Immune Estimation Resource (TIMER) site. Kaplan-Meier plotter, PrognoScan gene profile interactive...
In recent years, red cell distribution width (RDW) has been found to be associated with the prognosis of patients heart failure (HF) in Western countries. However, evidence from Asia is limited. We aimed investigate relationship between RDW and risk 3-month readmission hospitalized Chinese HF patients.We retrospectively analyzed data Fourth Hospital Zigong, Sichuan, China, involving 1,978 admitted for December 2016 June 2019. The independent variable our study was RDW, endpoint within 3...
Gastric cancer (GC), the most commonly diagnosed worldwide with poor 5-year survival rate in advanced stages. Although immune-related and survival-related biomarkers, which typically comprise aberrantly expressed long non-coding RNAs (lncRNAs) genes, have been identified, there are no reports of lncRNA pair (IRLP) signatures for GC.In this study, we acquired expression profiles from The Cancer Genome Atlas (TCGA) used least absolute shrinkage selection operator (LASSO) Cox proportional...
is a peer-reviewed open access academic journal that aims to guide clinical practice and improve diagnostic therapeutic skills of clinicians.WJGS covers topics concerning micro-invasive surgery; laparoscopy; hepatic, biliary, pancreatic splenic surgical nutrition; portal hypertension, as well associated subjects.The current columns WJGS include editorial, frontier, advances, therapeutics field vision, mini-reviews, review, topic highlight
Hepatoid adenocarcinoma of the stomach (HAS) is a particular subtype Gastric cancer (GC) with distinct pathological characteristics and genetic profile, but most HAS patients were received identical regimens as common GC. To date, only few studies has been conducted to investigate molecular HAS, which may prevent rational application new anticancer strategies. further obtain features potential predictive prognostic biomarkers our current study evaluated clinical implications spectrum markers...
The Notch signaling pathway has been identified as a therapeutic target for cancers. γ-Secretase inhibitors (GSIs) have progressively recognized potential anticancer drugs. present study aimed to investigate the effects of anti-delta like legend 4 (anti-DLL4) treatment on efficacy GSIs in gastric cancer. SGC-7901-GFP human cancer cells were tested DLL4 expression by rosette formation test and immunofluorescence, then treated with anti-DLL4 antibody...
Delayed gastric emptying (DGE) after distal gastrectomy impacts patients' nutritional status and quality of life. The current treatments DGE seem unsatisfactory or need invasive interventions. It is unknown whether transcutaneous electroacupuncture (TEA) effective in treating DGE.A total 90 eligible participants who underwent will be randomly allocated to either the TEA group (n = 60) sham (sham-TEA) 30). Each participant receive on bilateral acupoints Zusanli (ST36) Neiguan (PC6) for 4...
Tumor lysis syndrome (TLS) is an oncologic emergency that usually occurs after initial treatment of a malignant tumor. It manifests as hyperuricaemia, hyperkalaemia, hyperphosphataemia and hypocalcaemia, ultimately resulting in acute kidney failure, seizures, cardiac arrhythmias, even death. Here, we report very rare case spontaneous TLS patient with advanced gastric adenocarcinoma who eventually succumbed to renal failure. Extra vigilance towards electrolyte imbalances should be given...
Purpose: To investigate the effect of amoxicillin-clavulanate potassium and potential factors influencing umbilical cord separation time in preterm infants. Methods: A total 151 infants admitted to Neonatology Department, First Affiliated Hospital Anhui Medical University, Hefei, China, from November 2020 June 2021 were selected. Preterm randomly divided into control study groups. Control group received 2 % povidone-iodine 75 ethanol application, followed by gentle pressure with a cotton...