- Meat and Animal Product Quality
- Fatty Acid Research and Health
- Anesthesia and Sedative Agents
- Plant Pathogenic Bacteria Studies
- Ruminant Nutrition and Digestive Physiology
- Outdoor and Experiential Education
- Nausea and vomiting management
- Muscle metabolism and nutrition
- Pharmacological Effects and Assays
- Environmental Education and Sustainability
- CRISPR and Genetic Engineering
- Anesthesia and Neurotoxicity Research
- Plant Virus Research Studies
- Adipose Tissue and Metabolism
- Diverse Educational Innovations Studies
- Antioxidant Activity and Oxidative Stress
- Biochemical effects in animals
- Intensive Care Unit Cognitive Disorders
- Textile materials and evaluations
- Pesticide Exposure and Toxicity
- Cancer-related Molecular Pathways
- Ergonomics and Musculoskeletal Disorders
- Nanopore and Nanochannel Transport Studies
- Musculoskeletal pain and rehabilitation
- Agriculture Sustainability and Environmental Impact
St.Gallen University of Teacher Education
2022
ETH Zurich
2017-2020
Lawrence General Hospital
2018
Sana Klinikum Lichtenberg
2016
University of Tübingen
2015
Ludwig-Maximilians-Universität München
2012-2014
University of Bonn
2013
University Hospital Heidelberg
2004
Heidelberg University
2004
Éco-Anthropologie
1995
Transcription activator-like effector (TALE) proteins of the plant pathogenic bacterial genus Xanthomonas bind to and transcriptionally activate host susceptibility genes, promoting disease. Plant immune systems have taken advantage this mechanism by evolving TALE binding sites upstream resistance (R) genes. For example, pepper Bs3 rice Xa27 genes are hypersensitive reaction R that activated corresponding TALEs. Both a hallmark expression pattern in which their transcripts detectable only...
The tandem repeats of transcription activator like effectors (TALEs) mediate sequence-specific DNA binding using a simple code. Naturally, TALEs are injected by Xanthomonas bacteria into plant cells to manipulate the host transcriptome. In laboratory TALE domains reprogrammed and used target fused functional domain genomic locus choice. Research natural diversity TALE-like proteins may provide resources for further improvement current technology. Here we describe from endosymbiotic bacterium...
Transcription Activator-Like Effectors (TALEs) of Xanthomonas bacteria are programmable DNA binding proteins with unprecedented target specificity. Comparative studies into TALE repeat structure and function hindered by the limited sequence variation among repeats. More sequence-diverse TALE-like known from Ralstonia solanacearum (RipTALs) Burkholderia rhizoxinica (Bats), but RipTAL Bat repeats conserved those TALEs around DNA-binding residue. We study two novel marine-organism (MOrTL1...
During awake craniotomy, the patient's language centers are identified by neurological testing requiring a fully and cooperative patient. Hence, anesthesia aims for an unconscious patient at beginning end of surgery but responsive in between. We investigated plasma (Cplasma) effect-site (Ceffect-site) propofol concentration as well related Bispectral Index (BIS) required intraoperative return consciousness begin testing.In 13 patients, arterial Cplasma were measured high-pressure liquid...
Anaesthesia for awake craniotomy aims an unconscious patient at the beginning and end of surgery but a rapidly awakening responsive during period. Therefore, accurate pharmacokinetic/pharmacodynamic (PK/PD) model propofol is required to tailor depth anaesthesia.To compare predictive performances Marsh Schnider PK/PD models craniotomy.A prospective observational study.Single university hospital from February 2009 May 2010.Twelve patients undergoing elective resection brain tumour or...
Expanding the knowledge of issues that surround work-related injuries allows for development more successful work accident prevention policies, treatment and rehabilitation protocols, education programs. Specifically, clinical observation indicated many patients did not perceive or report circumstances injury as being part their regular duties. The objective this study was to investigate whether unusual activities at played any significant role in with disabling low back pain. Four hundred...
In this study, in vitro ruminal fermentation, anti-methanogenesis, and ammonia formation of two autotrophic algae [Nannochloropsis gaditana (NG), Phaeodactylum tricornutum (PT)], one heterotrophic alga [Schizochytrium sp. (SS)] were investigated. The experimental diets consisted a hay-concentrate basal diet (BD; 200 mg dry matter) supplemented with (1) no (just BD), (2) 40 dried NG (BD + NG), (3) PT PT), (4) 14 SS. total, 48 samples (four algal treatments × replicates three runs cows)...
The progression of clinically manifest premalignant lesions in the head and neck region to primary or second cancer is characterized by numerical structural chromosomal aberrations. However, many tumors arise from histologically inconspicuous mucosal sites. objective was investigate whether aberrations can be detected tumor-distant mucosa they help predict risk malignancy.A retrospective series 72 healthy, arbitrarily taken samples 53 patients with squamous cell carcinoma studied. A previous...
An interlaboratory trial was conducted for the validation of an enzyme-linked immunosorbent assay (ELISA) method determination appropriate heat treatment animal meal. A commercially available ELISA test kit developed identification beef in cooked food used study. Twelve laboratories from 7 European countries examined 2 different analytical protocols to establish most method. Three samples were used, waste materials sterilized at 129 and 134 degrees C (wet conditions), respectively, a meat...
Safety net community hospitals face unique challenges when entering risk-based contracts. The financial viability of such programs in these settings has not been well studied. This study analyzed a bundled-payment program for congestive heart failure at one facility. To assess performance, the authors calculated patient payment by quarter after bundle implementation, and also compared leading cost drivers before specifically next site care readmission rate. After 21 months participating...
Dietary polyunsaturated fatty acids (PUFA), especially n-3 and n-6 (FA), play an important role in the regulation of FA metabolism all mammals. However, differs between different organs, suggesting a distinct partitioning highly relevant FA. For present study cattle, novel technology was applied to overcome rumen biohydrogenation dietary unsaturated Angus heifers were fed straw-based diet supplemented for 8 weeks with 450 g/day rumen-protected oil, either from fish (FO) or sunflower (SO)....
Lipids are stored at various sites inside the body as adipose tissue (AT). These include subcutaneous, abdominal, and intermuscular locations. The AT substantially differ in their metabolic function. It is, however, unclear whether have specific requirements for individual essential n-3 n-6 fatty acids (FA). If so, control mechanisms would partition FA from blood. To investigate hypothesis of a selective incorporation, 18 beef heifers were fed diets supplemented with 60 g/kg diet lipids...
Wolf, C.; Ellerkmann, R.; Priston, M.; Neuloh, G.; Hoeft, A.; Soehle, M. Author Information