- Congenital Heart Disease Studies
- Tracheal and airway disorders
- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Coronary Artery Anomalies
- Congenital Diaphragmatic Hernia Studies
- Cardiac Arrhythmias and Treatments
- Transplantation: Methods and Outcomes
- Cardiac Valve Diseases and Treatments
- Cardiac pacing and defibrillation studies
- Infectious Aortic and Vascular Conditions
- Vascular anomalies and interventions
- Aortic Disease and Treatment Approaches
- Vascular Anomalies and Treatments
- Cardiac Arrest and Resuscitation
- Cardiovascular Issues in Pregnancy
- Infective Endocarditis Diagnosis and Management
- Esophageal and GI Pathology
- Cardiovascular and Diving-Related Complications
- Congenital heart defects research
- Trauma Management and Diagnosis
- Esophageal Cancer Research and Treatment
- IgG4-Related and Inflammatory Diseases
- Kawasaki Disease and Coronary Complications
- Dental Education, Practice, Research
Mount Sinai Hospital
2019-2025
Medical City Children's Hospital
2025
Mount Sinai Hospital
2019-2024
Icahn School of Medicine at Mount Sinai
2019-2024
Rady Children's Hospital-San Diego
2016-2023
Mount Sinai Medical Center
2020-2023
UPMC Health System
2021
University of California, San Diego
2017-2018
Mount Sinai Hospital
2018
Children's Medical Center
2015-2016
Mucosal-associated invariant T (MAIT) cells are a subset of lymphocytes that respond to microbial metabolites. We defined MAIT cell populations in different organs and characterized the developmental pathway mouse human thymus using single-cell RNA sequencing phenotypic metabolic analyses. showed predominant subset, which produced IL-17 (MAIT17), IFN-γ (MAIT1) had not only greatly transcriptomes but also states. MAIT17 exhibited increased lipid uptake, storage, mitochondrial potential...
Pulsatile flow left ventricular assist devices (LVADs) maximally unload the ventricle (LV), leading to reverse remodeling of myopathic LV that manifests as decreased end-diastolic dimension (LVEDD) and severity mitral regurgitation (MR). There is a paucity data, however, regarding ability continuous (CF) pumps adequately decompress induce similar remodeling. We sought evaluate effects CF-LVADs on From March 2006 through July 2011, one hundred patients with chronic heart failure underwent...
In this report, we describe the case of a 5-year-old male with SARS-CoV-2 associated MIS-C progressive respiratory failure and vasoplegic shock requiring extracorporeal support. At presentation, reverse transcription-polymerase chain reaction (RT-PCR) testing for was negative, however, SARS-CoV2 antibody positive. Multiple inflammatory markers cardiac biomarkers were elevated. Echocardiogram demonstrated mildly depressed left ventricular function no coronary anomalies noted. The patient...
ABSTRACT Introduction The present study aimed to assess the clinical outcomes of pediatric heart transplant patients whose donor hearts were preserved with SherpaPakCardiac Transport System. Methods All undergoing transplantation at our center between January 2020 and June 2024 included described. Vasoactive inotropic score (VIS) was calculated. cohort divided into two groups by recipient diagnoses (cardiomyopathy vs. congenital disease [CHD]). They compared based on demographics, operative...
Abstract Objective: To evaluate the outcomes of patients with single ventricle physiology supported extracorporeal membrane oxygenation as a bridge to first-stage palliation. Methods: This was retrospective registry-based study. Data from Extracorporeal Life Support Organization registry were used identify prior palliation 2016 2021. Descriptive statistics and multivariate analyses for associations mortality conducted. Results: Primary outcome death before hospital discharge. Patient...
As the aging population continues to increase, surgical needs of elderly will increase. The acute care surgery model has been developed in which trauma team also manages all general emergencies improve patient outcomes. We retrospectively reviewed our during past 5 years determine variables affecting major abdominal outcomes.Patients aged 80 and older who received an emergent operation by Acute Care Surgery between July 2000 November 2006 were included. assessed after-hours operations,...
Percutaneous circulatory support is widely available for use in adult patients. Options remain limited the pediatric population due to limitations of vessel and patient size, resulting more invasive means support. We present a case series patients whom Impella 2.5 axial flow pump was able be placed utilizing hybrid approach that allowed adequate distal perfusion while providing successful short‐term hemodynamic © 2013 Wiley Periodicals, Inc.
Bronchopleural fistula (BPF) is a connection between the bronchus and pleural cavity. It associated with high morbidity mortality management of BPF has not been well described in pediatric population. We describe 2-year-old girl who presented fever increased work breathing, found to have atypical hemolytic uremic syndrome Streptococcus necrotizing pneumonia development persistent air leak due bronchopleural fistulas requiring extracorporeal membrane oxygenation (ECMO). Three endobronchial...
The HeartWare HVAD has been used as a bridge to cardiac transplantation in the pediatric population. We describe outcomes following implantation at single center. A retrospective chart review was performed of all implants our institution between May 2013 and March 2015. Eight children ages 9 17 years underwent transplant (N = 7 cardiomyopathy, N 1 complex ventricle). There one operative death ventricle patient. Seven patients (87%) were successfully bridged transplant. Median time support...
Anomalous origin of the left coronary artery from pulmonary (ALCAPA) is a rare anomaly that carries 90% mortality in first year life when untreated. The diagnosis ALCAPA adulthood, and it includes broad spectrum clinical manifestations, including sudden cardiac death (SCD).We report case resuscitated arrest 55-year-old female, who was diagnosed with underwent successful surgical correction implantable cardioverter defibrillator (ICD) implantation for secondary prevention.ALCAPA not confined...
Pulmonary arteriovenous malformations (AVMs) can be a complication of certain postoperative Fontan patients whose hepatic venous blood return is not distributed evenly to both lungs. A ten-year-old female, who had previously undergone staged single ventricle palliation for complex congenital heart disease, underwent revision due significant left-sided pulmonary AVMs and increasing arterial oxygen desaturation. The combination four-dimensional flow cardiac magnetic resonance imaging...
Jiaxi He, Yunpeng Zhong, Hon-Chi Suen, Aditya Sengupta, Raghav A. Murthy, Eirch Stoelben, Angelo Carretta, Alper Toker, Chudong Wang, Jianxing Shuben Li