Alessandro Nini

ORCID: 0000-0002-2548-6495
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About
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Research Areas
  • Prostate Cancer Treatment and Research
  • Prostate Cancer Diagnosis and Treatment
  • Renal cell carcinoma treatment
  • Bladder and Urothelial Cancer Treatments
  • Testicular diseases and treatments
  • Multiple and Secondary Primary Cancers
  • Urologic and reproductive health conditions
  • Renal and related cancers
  • Cancer Diagnosis and Treatment
  • Sarcoma Diagnosis and Treatment
  • Economic and Financial Impacts of Cancer
  • Urinary Bladder and Prostate Research
  • Sexual function and dysfunction studies
  • Health Systems, Economic Evaluations, Quality of Life
  • Renal and Vascular Pathologies
  • Radiomics and Machine Learning in Medical Imaging
  • Hormonal and reproductive studies
  • Sexual Differentiation and Disorders
  • Ovarian cancer diagnosis and treatment
  • Cancer, Lipids, and Metabolism
  • Urological Disorders and Treatments
  • MRI in cancer diagnosis
  • Cardiac tumors and thrombi
  • Pancreatic and Hepatic Oncology Research
  • Metabolism, Diabetes, and Cancer

Ospedale San Bassiano
2023-2024

IRCCS Ospedale San Raffaele
2012-2023

Vita-Salute San Raffaele University
2014-2023

Saarland University
2020-2023

Istituti di Ricovero e Cura a Carattere Scientifico
2010-2022

Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2010-2022

Heinrich Heine University Düsseldorf
2017-2021

Universitätsklinikum des Saarlandes
2021

Ospedali Riuniti Umberto I
2017-2020

Hochschule Düsseldorf University of Applied Sciences
2019-2020

Little is known about how, during its formidable expansion in development and evolution, the cerebral cortex able to maintain correct balance between excitatory inhibitory neurons. In fact, while former are born within cortical primordium, latter originate outward ventral pallium. Therefore, it remains be addressed how these two neuronal populations might coordinate their relative amounts order build a functional network. Here, we show that Tbr2-positive intermediate (basal) progenitors...

10.1101/gad.575410 article EN Genes & Development 2010-08-15

Objectives To compare long‐term functional outcomes of off‐clamp or on‐clamp partial nephrectomy patients two high‐volume centers with cT1–2/N0 M0 renal tumors and baseline estimated glomerular filtration rate >60 mL/min. Methods A 3:1 propensity score‐matched analysis was used to select homogeneous cohorts versus nephrectomy. Joinpoint regression the 2–8‐year probabilities modifications in both selected cohorts. The Kaplan–Meier method assessed risk developing a stage ≥3b chronic kidney...

10.1111/iju.14079 article EN International Journal of Urology 2019-07-24

We compared the use of 11C-choline and 68Ga-prostate specific membrane antigen in men undergoing salvage lymph node dissection for nodal recurrent prostate cancer.The study included 641 patients who experienced rise recurrence after radical prostatectomy underwent dissection. Lymph was documented by positron emission tomography/computerized tomography using (407, 63%) or 68Ga-PSMA ligand (234, 37%). The outcome underestimation tumor burden (difference between number positive nodes on final...

10.1097/ju.0000000000000800 article EN The Journal of Urology 2020-03-18

No AccessJournal of UrologyAdult Urology1 Nov 2018Multiparametric Magnetic Resonance Imaging/Ultrasound Fusion Prostate Biopsy—Are 2 Biopsy Cores per Imaging Lesion Required? Pantelis Dimitroulis, Robert Rabenalt, Alessandro Nini, Andreas Hiester, Irene Esposito, Lars Schimmöller, Gerald Antoch, Peter Albers, and Christian Arsov DimitroulisPantelis Dimitroulis Department Urology, University Hospital Düsseldorf, Heinrich-Heine Medical Faculty, Germany , RabenaltRobert Rabenalt NiniAlessandro...

10.1016/j.juro.2018.05.002 article EN The Journal of Urology 2018-05-05

Background: Post-chemotherapy retroperitoneal lymph node dissection (PC-RPLND) plays a crucial role in treatment of metastatic non-seminomatous germ cell cancer. Objective: To evaluate the functional outcome regarding preservation ejaculatory function comparing bilateral vs. unilateral template resection PC-RPLND patients. In addition, oncological safety and perioperative complications was compared to full one. Design/Setting/Participants: Between 2003 2018, 504 RPLNDs have been performed...

10.3389/fsurg.2018.00080 article EN cc-by Frontiers in Surgery 2019-01-17

Robotic assisted retroperitoneal lymph node dissection in patients with testicular cancer is controversial. Lately, unusual recurrence patterns adverse outcomes after robotic have been published. In this report we determine the feasibility, safety and early oncologic outcome of small volume metastatic cancer.

10.1097/ju.0000000000001301 article EN The Journal of Urology 2020-07-27

To provide objective criteria for preoperative staging chest computed tomography (CT) in patients diagnosed with renal cell carcinoma (RCC) because, the absence of established indications, decision CT remains subjective.A total 1 946 undergoing surgical treatment RCC, whose data were collected a prospective institutional database, assessed. The outcome study was presence pulmonary metastases at CT. A multivariable logistic regression model predicting positive fitted. Predictors consisted...

10.1111/bju.13670 article EN BJU International 2016-09-29

Abstract Background Detection of circulating tumor cells (CTC) by techniques based on epithelial cell adhesion molecule (EpCAM) is suboptimal in urothelial carcinoma (UC). As HER2 thought to be broadly expressed UC, we explored its utility for CTC detection. Methods and EpCAM expression was analyzed 18 UC lines (UCCs) qRT‐PCR, western blot fluorescence‐activated scanning (FACS) compared the strongly HER2‐expressing breast cancer line SKBR3 other controls. patient tissues measured qRT PCR...

10.1002/cyto.b.21877 article EN cc-by-nc Cytometry Part B Clinical Cytometry 2020-03-25
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